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The map label for this gene is pgi [H]

Identifier: 13507989

GI number: 13507989

Start: 301113

End: 302405

Strand: Direct

Name: pgi [H]

Synonym: MPN250

Alternate gene names: 13507989

Gene position: 301113-302405 (Clockwise)

Preceding gene: 13507988

Following gene: 13507990

Centisome position: 36.88

GC content: 39.6

Gene sequence:

>1293_bases
ATGGAAAGTAAATGGTTAACAGTTGACACTAAGCACCTCTATGGTTTTGATGAAGCGATTTTTATTCAGAAATACCAAAA
AAAAGTTAACCAAATTCACCAACAGTTTTTAAATCAACAACTACCCGATGGTCACATGAATGGCTGGTATAGTCAACCCG
ATCAAGACCACAAGGGTTTGCTAAAACAAATTAACACAATTGCCAAACAGTTTAATGCTCTAAAAGTAACTGACATAGTG
TATTTAGGTATTGGTGGTTCTTATACTGGCATTCGTGCCATCTTAGACTTTTTAAAACCAGAACAGAAGGCGAATATCAA
AGTGCACTTTGTTCCTGACATATCGGCCTTTAACATTGCTGCAGTTGCTAGAGCAATTAAGGGTAAATCATGAGCTTTGG
TAGTAACTTCTAAATCTGGTCGCACACTCGAGCCGGCTGTTACCTTTCGGTACTTCCGTAATTTATTGCACAAACAATAC
AAGCAAAAACATGCTTTACGCACAGTTGTGATTACCGATGCCGTTAAGGGTTTACTAGTTGGCATGAGTAACCAGTACGG
TTATGCACACTTAACTATTCCAAGCAATATTGGTGGGCGTTTTTCAACTCTTTCACCCGCCGGTTTACTGTTAGCTAAAC
TTTGTGGTCATGATCCGAAACAGCTCTTATTGGGTACTTTGACAGCCAAACAAGAGTTAGCAAACAGTGATTTAAACACT
AATTCGGCTTATTATTATGCTGCTTTGCGTCACTGACTTTACACGACAAAGAAGCTCAAAATAGAAGTGACGGTAGCATA
CCACAGTGCTTATGAGTACCTCTTGTTGCAACACCGCCAACTGTTCGGTGAATCAGAGGGTAAAGGTGGTAAGTCCCTGT
TCCCTACCTTTTCGCTATTTACCACTGACTTACACTCAATGGGGCAGTTGTACCAAGAAGGGGAAAAGAACTTCTTTGAA
ACAGTGATACAAGTGCAAACACAATTTCACGACTTGGAACTACCACCATCAGACTTTAACAATGATGATCAGCTAGATTA
CTTATTGGCTAAAAGTATGAATGAAATTTCAAACACTGCCCTAGAAGCAGTTGTGGAAGCTCATTTTCAATCAAACGTTA
ACATCATTAAGTTAACGCTCAAAGAAAGAACAACCTTTATGTTTGGTTACTTTTACTTCTGGTTATCAATGGCCACAATG
ATGAGTGGTTCACTGCTGGGACACAACGTCTTTGATCAACCAGGGGTGGAAGTGTACAAGCAGTTAATGTTTGCTAAACT
TGGTCGTGAATAG

Upstream 100 bases:

>100_bases
TTGTTTTATTGTAAGTGCTGTAACCCAAAAATCGTATTCCTTGTGACTTTATGAGAGCTATCTAAAGTTGATTAATTAAA
ATCAACTAAAAAAAGGATTT

Downstream 100 bases:

>100_bases
GGAAATTGCCTTTTCGCTTTTACCACTGTTACACCAGTTTGACCGCAAGTTGTTAGAACAATTCTTTGCGGACGGCTTGC
GCTTAATCCACTATGACGTG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGLLKQINTIAKQFNALKVTDIV
YLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIAAVARAIKGKSWALVVTSKSGRTLEPAVTFRYFRNLLHKQY
KQKHALRTVVITDAVKGLLVGMSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNT
NSAYYYAALRHWLYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTTDLHSMGQLYQEGEKNFFE
TVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALEAVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATM
MSGSLLGHNVFDQPGVEVYKQLMFAKLGRE

Sequences:

>Translated_430_residues
MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGLLKQINTIAKQFNALKVTDIV
YLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIAAVARAIKGKS*ALVVTSKSGRTLEPAVTFRYFRNLLHKQY
KQKHALRTVVITDAVKGLLVGMSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNT
NSAYYYAALRH*LYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTTDLHSMGQLYQEGEKNFFE
TVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALEAVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATM
MSGSLLGHNVFDQPGVEVYKQLMFAKLGRE
>Mature_430_residues
MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGLLKQINTIAKQFNALKVTDIV
YLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIAAVARAIKGKS*ALVVTSKSGRTLEPAVTFRYFRNLLHKQY
KQKHALRTVVITDAVKGLLVGMSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNT
NSAYYYAALRH*LYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTTDLHSMGQLYQEGEKNFFE
TVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALEAVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATM
MSGSLLGHNVFDQPGVEVYKQLMFAKLGRE

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 48426; Mature: 48426

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGL
CCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LKQINTIAKQFNALKVTDIVYLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIA
HHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHH
AVARAIKGKSALVVTSKSGRTLEPAVTFRYFRNLLHKQYKQKHALRTVVITDAVKGLLVG
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNTN
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SAYYYAALRHLYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTT
CHHHHHHHHHHHHCCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
DLHSMGQLYQEGEKNFFETVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATMMSGSLLGHNVFDQPGVEVYKQL
HHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHH
MFAKLGRE
HHHHHCCC
>Mature Secondary Structure
MESKWLTVDTKHLYGFDEAIFIQKYQKKVNQIHQQFLNQQLPDGHMNGWYSQPDQDHKGL
CCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LKQINTIAKQFNALKVTDIVYLGIGGSYTGIRAILDFLKPEQKANIKVHFVPDISAFNIA
HHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHH
AVARAIKGKSALVVTSKSGRTLEPAVTFRYFRNLLHKQYKQKHALRTVVITDAVKGLLVG
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSNQYGYAHLTIPSNIGGRFSTLSPAGLLLAKLCGHDPKQLLLGTLTAKQELANSDLNTN
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SAYYYAALRHLYTTKKLKIEVTVAYHSAYEYLLLQHRQLFGESEGKGGKSLFPTFSLFTT
CHHHHHHHHHHHHCCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
DLHSMGQLYQEGEKNFFETVIQVQTQFHDLELPPSDFNNDDQLDYLLAKSMNEISNTALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AVVEAHFQSNVNIIKLTLKERTTFMFGYFYFWLSMATMMSGSLLGHNVFDQPGVEVYKQL
HHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHH
MFAKLGRE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]