Click here to switch to the map view.

The map label for this gene is infA

Identifier: 13507926

GI number: 13507926

Start: 230343

End: 230579

Strand: Direct

Name: infA

Synonym: MPN187

Alternate gene names: 13507926

Gene position: 230343-230579 (Clockwise)

Preceding gene: 13507925

Following gene: 13507927

Centisome position: 28.21

GC content: 40.51

Gene sequence:

>237_bases
ATGCAACCAAAGTTTAATAACCAAGCAAAGCAGGACAAACTCGTCTTAACGGGCAAAATCTTGGAAATCATCCACGGTGA
CAAGTTTCGCGTGTTGTTGGAAAACAACGTTGAAGTAGATGCTCACTTAGCGGGCAAAATGCGAATGCGCCGGTTACGAA
TTTTACCGGGCGATTTAGTTGAAGTGGAATTTTCCCCTTATGATTTAAAGTTAGGTCGAATAATAGGTAGAAAATAA

Upstream 100 bases:

>100_bases
ACAACAGCTGGAATGTATTAACCCCTAAAAGCCGTTACAATTGTCATGTAGAACAGATGTATGTGATCACCACAAGTGGA
TTTGAATGTTTAACTAATTA

Downstream 100 bases:

>100_bases
TTAAAATACTATGAAAGTTAGAGCGAGCGTAAAGCCAATTTGCAAAGATTGCAAGATCATTAAGCGCCACCAAATTGTGC
GCGTTATTTGCAAAACTCAA

Product: initiation factor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 78; Mature: 78

Protein sequence:

>78_residues
MQPKFNNQAKQDKLVLTGKILEIIHGDKFRVLLENNVEVDAHLAGKMRMRRLRILPGDLVEVEFSPYDLKLGRIIGRK

Sequences:

>Translated_78_residues
MQPKFNNQAKQDKLVLTGKILEIIHGDKFRVLLENNVEVDAHLAGKMRMRRLRILPGDLVEVEFSPYDLKLGRIIGRK
>Mature_78_residues
MQPKFNNQAKQDKLVLTGKILEIIHGDKFRVLLENNVEVDAHLAGKMRMRRLRILPGDLVEVEFSPYDLKLGRIIGRK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=50, Blast_Score=70, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_MYCPN (Q50298)

Other databases:

- EMBL:   U34795
- EMBL:   U00089
- PIR:   S62821
- RefSeq:   NP_109875.1
- ProteinModelPortal:   Q50298
- SMR:   Q50298
- GeneID:   877185
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN187
- HOGENOM:   HBG286099
- OMA:   EFSPYDL
- ProtClustDB:   PRK00276
- BioCyc:   MPNE272634:MPN187-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 9025; Mature: 9025

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPKFNNQAKQDKLVLTGKILEIIHGDKFRVLLENNVEVDAHLAGKMRMRRLRILPGDLV
CCCCCCCCCCCCEEEEEHHEEEECCCCEEEEEECCCCEEEEEECCHHHEEEEECCCCCEE
EVEFSPYDLKLGRIIGRK
EEEECCCEEEECEEECCC
>Mature Secondary Structure
MQPKFNNQAKQDKLVLTGKILEIIHGDKFRVLLENNVEVDAHLAGKMRMRRLRILPGDLV
CCCCCCCCCCCCEEEEEHHEEEECCCCEEEEEECCCCEEEEEECCHHHEEEEECCCCCEE
EVEFSPYDLKLGRIIGRK
EEEECCCEEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8604303; 8948633; 11271496