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The map label for this gene is infC [H]

Identifier: 13507854

GI number: 13507854

Start: 150643

End: 151248

Strand: Direct

Name: infC [H]

Synonym: MPN115

Alternate gene names: 13507854

Gene position: 150643-151248 (Clockwise)

Preceding gene: 13507853

Following gene: 13507855

Centisome position: 18.45

GC content: 38.78

Gene sequence:

>606_bases
ATGCCGTTGATTCTTGATCAGGGCTGTTTTGTTAGTGAAAGTAGATTTCATAGATTGGCACAGAACATAAAACAAGGTTC
CAGGCGTGAGCGCGAACAAAAACCGTTAATTAACGATAAAATTGGCTTTAATGAGTTCATTTTAATTGACGAAAATGGCT
CCAATTTGGGGACGGTTAGAAGGACCGATGCCCTCAAGATGGCTGAGGAAAAACAACTCGATTTAGTCTTAATTGGTTCA
AACCCAGCCAAACCCATTGTTAAGCTCTTAGACTTTGGTCGTTACACTTATGATTTAAAACGCAAAAAACGCCAGTCCAA
GAAAAACCAAACCATTATCCAAATAAAGGAAGTGGTAGTGAAACCGACAATCGCTAAACATGATCTGGAATTTAAAGCTA
AGCAAACGACGGGATGAGCTGAAAAGGGTTATCACGTTAAGTTTGTAGTGCGCGCTTTTGGTAGAGTAAGTACTAGGATT
GAGTTAATTGAAAAAGTCTTTAATGACTTTTATCTGCTAGTAGAACCAGCAGTGGAGGTCCAAAAACCACTAACTGCTTC
TTCCAAAACAATGTATTCTGCTTTGTTAGTTCCCCGTAAGAAATAA

Upstream 100 bases:

>100_bases
CTCTTAAATAAAATTACTCCTTAATGGTTAATTGAGTTAAAACGGTTGGAGATTGTTAAAATATTGGCGCTATACAAAGT
AGTCTTTACGACTCGCCCGA

Downstream 100 bases:

>100_bases
AAATTATGAAAGTAAAAAGTGCTGCAAAGAAGCGTTTTAAGCTCACTAAGTCTGGCCAAATTAAGCGCAAACACGCTTAT
ACTTCCCACTTAGCACCGCA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MPLILDQGCFVSESRFHRLAQNIKQGSRREREQKPLINDKIGFNEFILIDENGSNLGTVRRTDALKMAEEKQLDLVLIGS
NPAKPIVKLLDFGRYTYDLKRKKRQSKKNQTIIQIKEVVVKPTIAKHDLEFKAKQTTGWAEKGYHVKFVVRAFGRVSTRI
ELIEKVFNDFYLLVEPAVEVQKPLTASSKTMYSALLVPRKK

Sequences:

>Translated_201_residues
MPLILDQGCFVSESRFHRLAQNIKQGSRREREQKPLINDKIGFNEFILIDENGSNLGTVRRTDALKMAEEKQLDLVLIGS
NPAKPIVKLLDFGRYTYDLKRKKRQSKKNQTIIQIKEVVVKPTIAKHDLEFKAKQTTG*AEKGYHVKFVVRAFGRVSTRI
ELIEKVFNDFYLLVEPAVEVQKPLTASSKTMYSALLVPRKK
>Mature_200_residues
PLILDQGCFVSESRFHRLAQNIKQGSRREREQKPLINDKIGFNEFILIDENGSNLGTVRRTDALKMAEEKQLDLVLIGSN
PAKPIVKLLDFGRYTYDLKRKKRQSKKNQTIIQIKEVVVKPTIAKHDLEFKAKQTTG*AEKGYHVKFVVRAFGRVSTRIE
LIEKVFNDFYLLVEPAVEVQKPLTASSKTMYSALLVPRKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=183, Percent_Identity=30.0546448087432, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22941; Mature: 22810

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLILDQGCFVSESRFHRLAQNIKQGSRREREQKPLINDKIGFNEFILIDENGSNLGTVR
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEE
RTDALKMAEEKQLDLVLIGSNPAKPIVKLLDFGRYTYDLKRKKRQSKKNQTIIQIKEVVV
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KPTIAKHDLEFKAKQTTGAEKGYHVKFVVRAFGRVSTRIELIEKVFNDFYLLVEPAVEVQ
CCCHHHCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHH
KPLTASSKTMYSALLVPRKK
CCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLILDQGCFVSESRFHRLAQNIKQGSRREREQKPLINDKIGFNEFILIDENGSNLGTVR
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEE
RTDALKMAEEKQLDLVLIGSNPAKPIVKLLDFGRYTYDLKRKKRQSKKNQTIIQIKEVVV
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KPTIAKHDLEFKAKQTTGAEKGYHVKFVVRAFGRVSTRIELIEKVFNDFYLLVEPAVEVQ
CCCHHHCCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHH
KPLTASSKTMYSALLVPRKK
CCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]