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The map label for this gene is cpsG [H]

Identifier: 13507805

GI number: 13507805

Start: 82081

End: 83745

Strand: Direct

Name: cpsG [H]

Synonym: MPN066

Alternate gene names: 13507805

Gene position: 82081-83745 (Clockwise)

Preceding gene: 13507804

Following gene: 13507814

Centisome position: 10.05

GC content: 42.64

Gene sequence:

>1665_bases
ATGAACAGTAACGCATACTTGGAAGCTCAAAGGTGGCTAAGCCATCCGCGGGTAAAACCCAACTTAAAGGAGGTCATTAC
GGCTATGAGTGCTGAGGAAATCGAGCACTTCTTTAGCTTAAAGAAACCGAGTTTTGGCACTGCTGGGGTACGGGGCAAAA
TGGCACCGGGGTACCATGGGATGAATGTGTTTTCCTATGCTTACTTAACCCAGGGTTATGTCAACTACATCCAGTCGTTA
AACCCAACTAAAAAACCATTACGCTTTTTAGTAGCCAGAGACACTAGAAAACACGGGGCATTGTTTAATGGCATTGTGTG
TGATGTGATTACCTCTATGGGTCATGTGGTCTATATGTTTGATAACAATGAACCAACACCAACACCATTAGTATCTTATG
TGATTAAGAAGTACCACTTTGATGGTGGGGTGAATGTCACTGCTAGTCATAATCCTAAAACCGATAATGGCTTTAAGATT
TACGATGGTCATGGCGCGCAGTTACTAGACTTCCAAACTGATCAATTAATCGCAATGTTACCCCCAGTGGTAACAATGTT
AGATTTCGAACCACGTGGTAACAACGAGCTGTTACACTTTTTGGATAACGAAGTGGTCTACAAAAACTACTTTGATGATC
TTAAGGAAAGCCTAGTAGTGGACAACGACAGCTTTAAAAACCTCCCGGTGGTCTTTACCGGGTTACATGGTACTTCGGTG
AAGTTGTTACCAAGGTTTTTAACCTATTTGGGTTACAGCAACATTATTAGTGTCCAACCACAAAACGTGTTTGACGCTAA
CTTTGCTAATGCTGACCACCTCAACCCCGAAAGTAAGGATACCTGAGAGTTAGCGCGACAGTATGCATCCAACACTAAGG
CCAAGTTAATGATGGCAATTGATCCGGATGCTGATCGCTTTGCGATTGCCGAATGAAATCCGCAAACCCAAGACTGGCAC
TACTTCTCCGGGAACGAGTCAGGAGTTATGGTGGCTTACTATAAGCTCAAACACAAGCAGTTTAAGCGTCAACCTTACAT
TGTAACGACGGTAGTCTCTACTGATCTAGTGGATAAGATTGCCAAGAAGTACGGGGCTTTTGTCAAGCGCACAAATGTCG
GCTTTAAGTTTATTGGTCAAGCTGTTAATCACTTCTCCAAAGACAATGAACTAGTAGTGGCCTTTGAAGAAGCGATTGGT
ATGATGGCTAGTGATGGTTTGAACCGCGAAAAGGATTCCTTTCAAGCAGCGGCCATCATGCTTGAAATTGCGCGCTACTG
TCATAATAAAGGAATTAGCTTACTAGAGTTCTACCGTGGTGAGATCTTCGGTGAATTTGGTGATTACTATAACTGAACGG
TACCACACACCATTCACGGAGTTAACTGGAAGGAAAAAATGGAACAGGTATTACACCAGTTAACCACAGCTACCATTAAA
GAGGTTGTGGGACACAAGATTACCAAGATTAAAAACTATGTCGACATTAACCTAGTCGAATATGTCTTGGAAAACGGTAA
CTGGATTAAGTTCCGCATTTCCGGTACAGAACCGAAGTTAAAGCTGTACTTTAACCTATCTAACGGTTACTTAGCAGCTT
TAAAACACGAAGCGAAAAAGATGCACGAGTTCCTAGTGCGATTGCTCAACCTCGATAAAGCTTAG

Upstream 100 bases:

>100_bases
GAGTTTGCCACTGATAAGACCCAGTTATTCTGCATTGAGAAGGACAAGAGCTTTAAACAATTTACTATTCCCGAAATTTT
AAAGGGAGGTTTTCGATCAT

Downstream 100 bases:

>100_bases
GTTTTCTAAAGGCAAGTTAATTAACTGCGTTTTGGTGGTTAATTCGACTTCCACTACCGCTTTGTTAATTGTTCCTTGGT
ATAGAGCCTTAATTTGACCT

Product: phosphomannomutase/phosphoglucomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MNSNAYLEAQRWLSHPRVKPNLKEVITAMSAEEIEHFFSLKKPSFGTAGVRGKMAPGYHGMNVFSYAYLTQGYVNYIQSL
NPTKKPLRFLVARDTRKHGALFNGIVCDVITSMGHVVYMFDNNEPTPTPLVSYVIKKYHFDGGVNVTASHNPKTDNGFKI
YDGHGAQLLDFQTDQLIAMLPPVVTMLDFEPRGNNELLHFLDNEVVYKNYFDDLKESLVVDNDSFKNLPVVFTGLHGTSV
KLLPRFLTYLGYSNIISVQPQNVFDANFANADHLNPESKDTWELARQYASNTKAKLMMAIDPDADRFAIAEWNPQTQDWH
YFSGNESGVMVAYYKLKHKQFKRQPYIVTTVVSTDLVDKIAKKYGAFVKRTNVGFKFIGQAVNHFSKDNELVVAFEEAIG
MMASDGLNREKDSFQAAAIMLEIARYCHNKGISLLEFYRGEIFGEFGDYYNWTVPHTIHGVNWKEKMEQVLHQLTTATIK
EVVGHKITKIKNYVDINLVEYVLENGNWIKFRISGTEPKLKLYFNLSNGYLAALKHEAKKMHEFLVRLLNLDKA

Sequences:

>Translated_554_residues
MNSNAYLEAQRWLSHPRVKPNLKEVITAMSAEEIEHFFSLKKPSFGTAGVRGKMAPGYHGMNVFSYAYLTQGYVNYIQSL
NPTKKPLRFLVARDTRKHGALFNGIVCDVITSMGHVVYMFDNNEPTPTPLVSYVIKKYHFDGGVNVTASHNPKTDNGFKI
YDGHGAQLLDFQTDQLIAMLPPVVTMLDFEPRGNNELLHFLDNEVVYKNYFDDLKESLVVDNDSFKNLPVVFTGLHGTSV
KLLPRFLTYLGYSNIISVQPQNVFDANFANADHLNPESKDT*ELARQYASNTKAKLMMAIDPDADRFAIAE*NPQTQDWH
YFSGNESGVMVAYYKLKHKQFKRQPYIVTTVVSTDLVDKIAKKYGAFVKRTNVGFKFIGQAVNHFSKDNELVVAFEEAIG
MMASDGLNREKDSFQAAAIMLEIARYCHNKGISLLEFYRGEIFGEFGDYYN*TVPHTIHGVNWKEKMEQVLHQLTTATIK
EVVGHKITKIKNYVDINLVEYVLENGNWIKFRISGTEPKLKLYFNLSNGYLAALKHEAKKMHEFLVRLLNLDKA
>Mature_554_residues
MNSNAYLEAQRWLSHPRVKPNLKEVITAMSAEEIEHFFSLKKPSFGTAGVRGKMAPGYHGMNVFSYAYLTQGYVNYIQSL
NPTKKPLRFLVARDTRKHGALFNGIVCDVITSMGHVVYMFDNNEPTPTPLVSYVIKKYHFDGGVNVTASHNPKTDNGFKI
YDGHGAQLLDFQTDQLIAMLPPVVTMLDFEPRGNNELLHFLDNEVVYKNYFDDLKESLVVDNDSFKNLPVVFTGLHGTSV
KLLPRFLTYLGYSNIISVQPQNVFDANFANADHLNPESKDT*ELARQYASNTKAKLMMAIDPDADRFAIAE*NPQTQDWH
YFSGNESGVMVAYYKLKHKQFKRQPYIVTTVVSTDLVDKIAKKYGAFVKRTNVGFKFIGQAVNHFSKDNELVVAFEEAIG
MMASDGLNREKDSFQAAAIMLEIARYCHNKGISLLEFYRGEIFGEFGDYYN*TVPHTIHGVNWKEKMEQVLHQLTTATIK
EVVGHKITKIKNYVDINLVEYVLENGNWIKFRISGTEPKLKLYFNLSNGYLAALKHEAKKMHEFLVRLLNLDKA

Specific function: Unknown

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=558, Percent_Identity=27.4193548387097, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI31377548, Length=584, Percent_Identity=25.8561643835616, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1789566, Length=256, Percent_Identity=23.4375, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=521, Percent_Identity=28.7907869481766, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71993878, Length=277, Percent_Identity=31.4079422382672, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323934, Length=573, Percent_Identity=28.9703315881326, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129809, Length=568, Percent_Identity=26.7605633802817, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24651977, Length=489, Percent_Identity=27.19836400818, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24653722, Length=594, Percent_Identity=23.0639730639731, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 62603; Mature: 62603

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNAYLEAQRWLSHPRVKPNLKEVITAMSAEEIEHFFSLKKPSFGTAGVRGKMAPGYHG
CCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MNVFSYAYLTQGYVNYIQSLNPTKKPLRFLVARDTRKHGALFNGIVCDVITSMGHVVYMF
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
DNNEPTPTPLVSYVIKKYHFDGGVNVTASHNPKTDNGFKIYDGHGAQLLDFQTDQLIAML
ECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCEEEECCHHHHHHHH
PPVVTMLDFEPRGNNELLHFLDNEVVYKNYFDDLKESLVVDNDSFKNLPVVFTGLHGTSV
CCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCHH
KLLPRFLTYLGYSNIISVQPQNVFDANFANADHLNPESKDTELARQYASNTKAKLMMAID
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEC
PDADRFAIAENPQTQDWHYFSGNESGVMVAYYKLKHKQFKRQPYIVTTVVSTDLVDKIAK
CCCCCEEEECCCCCCCCEEECCCCCCEEEEEEEHHHHHHCCCCEEEEEEHHHHHHHHHHH
KYGAFVKRTNVGFKFIGQAVNHFSKDNELVVAFEEAIGMMASDGLNREKDSFQAAAIMLE
HHHHHHEECCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHH
IARYCHNKGISLLEFYRGEIFGEFGDYYNTVPHTIHGVNWKEKMEQVLHQLTTATIKEVV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GHKITKIKNYVDINLVEYVLENGNWIKFRISGTEPKLKLYFNLSNGYLAALKHEAKKMHE
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHH
FLVRLLNLDKA
HHHHHHCCCCC
>Mature Secondary Structure
MNSNAYLEAQRWLSHPRVKPNLKEVITAMSAEEIEHFFSLKKPSFGTAGVRGKMAPGYHG
CCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MNVFSYAYLTQGYVNYIQSLNPTKKPLRFLVARDTRKHGALFNGIVCDVITSMGHVVYMF
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEE
DNNEPTPTPLVSYVIKKYHFDGGVNVTASHNPKTDNGFKIYDGHGAQLLDFQTDQLIAML
ECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCEEEECCHHHHHHHH
PPVVTMLDFEPRGNNELLHFLDNEVVYKNYFDDLKESLVVDNDSFKNLPVVFTGLHGTSV
CCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCHH
KLLPRFLTYLGYSNIISVQPQNVFDANFANADHLNPESKDTELARQYASNTKAKLMMAID
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEC
PDADRFAIAENPQTQDWHYFSGNESGVMVAYYKLKHKQFKRQPYIVTTVVSTDLVDKIAK
CCCCCEEEECCCCCCCCEEECCCCCCEEEEEEEHHHHHHCCCCEEEEEEHHHHHHHHHHH
KYGAFVKRTNVGFKFIGQAVNHFSKDNELVVAFEEAIGMMASDGLNREKDSFQAAAIMLE
HHHHHHEECCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHH
IARYCHNKGISLLEFYRGEIFGEFGDYYNTVPHTIHGVNWKEKMEQVLHQLTTATIKEVV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GHKITKIKNYVDINLVEYVLENGNWIKFRISGTEPKLKLYFNLSNGYLAALKHEAKKMHE
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHH
FLVRLLNLDKA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]