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The map label for this gene is cdd [H]

Identifier: 13507804

GI number: 13507804

Start: 81690

End: 82091

Strand: Direct

Name: cdd [H]

Synonym: MPN065

Alternate gene names: 13507804

Gene position: 81690-82091 (Clockwise)

Preceding gene: 13507803

Following gene: 13507805

Centisome position: 10.01

GC content: 40.3

Gene sequence:

>402_bases
ATGAAAGTTGATTTAGATTGAGTCCACCACAAGTTACAGGAGGTGGTCAATCATGCCTACACGCCTTTTTCAAAGTTTAA
GGTAGCTTGTATGTTGGTGGCCAATAACCAGGCATTTTATGGAGTCAATATTGAAAACGCTTCTTACCCAGTAACCCTGT
GTGCGGAACGTAGTGCGATTGCTAACATGGTCACTAGTATCGGCAAGGCCACAATTGATTATGTCTTTGTGTACTTTGAC
ACTAAAACTCCAACCAATTCACCTTGTGGCATGTGTCGGCAAAACATCTTTGAGTTTGCCACTGATAAGACCCAGTTATT
CTGCATTGAGAAGGACAAGAGCTTTAAACAATTTACTATTCCCGAAATTTTAAAGGGAGGTTTTCGATCATATGAACAGT
AA

Upstream 100 bases:

>100_bases
GGGGACACAGTCTTAGAACTTTACAGCTCCAAACCAATTACGCCTGCCCACATAGAAGCTGCGCAGCACACCATTATTAT
TAAGCAGTAAATAAACCTCA

Downstream 100 bases:

>100_bases
CGCATACTTGGAAGCTCAAAGGTGGCTAAGCCATCCGCGGGTAAAACCCAACTTAAAGGAGGTCATTACGGCTATGAGTG
CTGAGGAAATCGAGCACTTC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MKVDLDWVHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIANMVTSIGKATIDYVFVYFD
TKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIPEILKGGFRSYEQ

Sequences:

>Translated_133_residues
MKVDLD*VHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIANMVTSIGKATIDYVFVYFD
TKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIPEILKGGFRSYEQ
>Mature_133_residues
MKVDLD*VHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIANMVTSIGKATIDYVFVYFD
TKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIPEILKGGFRSYEQ

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=117, Percent_Identity=36.7521367521368, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540514, Length=97, Percent_Identity=40.2061855670103, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551074, Length=93, Percent_Identity=41.9354838709677, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323274, Length=112, Percent_Identity=34.8214285714286, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14981; Mature: 14981

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDLDVHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIA
CCCCCHHHHHHHHHHHHCCCCCCHHEEEEEEEECCCEEEEEEECCCCCCEEEECCHHHHH
NMVTSIGKATIDYVFVYFDTKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIP
HHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCH
EILKGGFRSYEQ
HHHHHHHCCCCC
>Mature Secondary Structure
MKVDLDVHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIA
CCCCCHHHHHHHHHHHHCCCCCCHHEEEEEEEECCCEEEEEEECCCCCCEEEECCHHHHH
NMVTSIGKATIDYVFVYFDTKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIP
HHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCH
EILKGGFRSYEQ
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]