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The map label for this gene is 13507786

Identifier: 13507786

GI number: 13507786

Start: 55942

End: 57297

Strand: Direct

Name: 13507786

Synonym: MPN047

Alternate gene names: NA

Gene position: 55942-57297 (Clockwise)

Preceding gene: 13507785

Following gene: 13507787

Centisome position: 6.85

GC content: 41.89

Gene sequence:

>1356_bases
ATGGTCCAAACACCCAGTGAAATAAATACCCACCTTAAACACCTCTTGGCCTGTGATGCTTATAAGCTATCACACCGCTT
AATGTATCCTAATGACACGACCAACTTATACAGTTGTTTAACAGCCCGGGGTGGTCGTGGTGGTTTTCCAAATTTTGTGT
GAAACCACGAGTTTGCCAAAAAGATTATTCTTGAAGTGTTTGGTAACTTTTGTGATAGTGTGTTAGCAGTCCAAAACGAT
CCTGGGTTGGCCCAAGCGCTCACTGACAAGGTGACCACTGTTTTTGGTGATCCCCAGTTTGGGTTGGAGTTTACCCAGCA
CATCTGTTATTTAGCTAACTTTTTAAAACAACACCACCAGTTACCCTTAACGGTAAAGATTCACCAGAGTTCTGAGGGTT
TAGCCTTCCGTACACCCTTAGTAACTATTACAGGTTCGGACCAAATGGTTCCCGAGTTAGTTTGGTTAGTCAACTATTTT
GAAACCGTATTATTGGAAAACATCTGATTGTACCAAACTACTTTAACTGTCGCCCAAAGCTTAAAGCTGCTGTTGGAACG
CTATGCTAACGAAACCGCGGATAATACTGAATTTACCCACTTTCAGTGTCATGATTTTAGTATGCGTGGTATGAGTAGTC
TTCAAAGTGCTTTATATGTAGCTAATGCTCACCTGCAGTACTTTAGTGGCAGTGACACCATTTTAGGCGGTGTAGCTGCT
AAATCGATCTTAGCTAGTGAACACTCGGTGATGTGTGCTGATGGTCAAGAGGGTGAATTGAATACCTTTAAACGTTTATT
GGAGCAGTTTCCTAACAAAAATCTGTCCTTAGTGATTGATTCTTATGACATGTGGCATGTTCTAGATAACATCTTACCCC
AACTCAAGGACTTAGTTTTACAACGACAGGAGAAGCTGTACCTCCGACCTGACTCGGGCAACTTTGAAACCCTTATTTGT
CAGGGCAAACGGTTTAACCCCGAGGACAAAACTACCTGGGGAGTAATTGATTACTTAGATTACCACTTTGGTTCCACTGT
TAACCAAAAAGGTTATAAGGTTTTGAACCAAAAGTTGGGTATTGTTTATGGCGATGGCATTACCTATGAGCGGATTGAGT
ACATTTTGGAACAGCTCAAACAACGTGGGTTTTGTTCTTCCAACATTGTCTTTGGGGTTGGTAGTACAACTTACCAAAAC
CTTAACCGTGATACGTTGGGATTTGTGTATAAGTTGACAGCCATCAAAAAGGGTAATACCTGACATGATGTTACCAAGAG
TCCCATAACCGATCCCACCAAGCAGTCCATAGGGGGACGATTTGATAACCCCAACCTAATTCAGGTTTACGGTTAA

Upstream 100 bases:

>100_bases
ACAACATTAGGGAAGTGATGGCCTTTCCGAAAAATGCCCAAGGGATAGAGATGCACACTAATGCCCCTGATCAGGTTGAC
ATTAAAGACATAACAACAAT

Downstream 100 bases:

>100_bases
TGCACCTCAAAAAACCGTTAGTGGTTACTAAGGATTGCTTTTATTGACTTAGTTTCGGATCGCTAAAATGATTGTTAGCA
CCAATCTTTTTAAAATTTTC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFVWNHEFAKKIILEVFGNFCDSVLAVQND
PGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQLPLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYF
ETVLLENIWLYQTTLTVAQSLKLLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAA
KSILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQRQEKLYLRPDSGNFETLIC
QGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIVYGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQN
LNRDTLGFVYKLTAIKKGNTWHDVTKSPITDPTKQSIGGRFDNPNLIQVYG

Sequences:

>Translated_451_residues
MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFV*NHEFAKKIILEVFGNFCDSVLAVQND
PGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQLPLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYF
ETVLLENI*LYQTTLTVAQSLKLLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAA
KSILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQRQEKLYLRPDSGNFETLIC
QGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIVYGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQN
LNRDTLGFVYKLTAIKKGNT*HDVTKSPITDPTKQSIGGRFDNPNLIQVYG
>Mature_451_residues
MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFV*NHEFAKKIILEVFGNFCDSVLAVQND
PGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQLPLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYF
ETVLLENI*LYQTTLTVAQSLKLLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAA
KSILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQRQEKLYLRPDSGNFETLIC
QGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIVYGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQN
LNRDTLGFVYKLTAIKKGNT*HDVTKSPITDPTKQSIGGRFDNPNLIQVYG

Specific function: Unknown

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Homo sapiens, GI5031977, Length=443, Percent_Identity=29.5711060948081, Blast_Score=166, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR016471
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: NA

Molecular weight: Translated: 50491; Mature: 50491

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFVNHEFAKK
CCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
IILEVFGNFCDSVLAVQNDPGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCC
PLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYFETVLLENILYQTTLTVAQSLK
CEEEEEECCCCCCEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAAKS
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHHHHH
ILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQR
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
QEKLYLRPDSGNFETLICQGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIV
HHCEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
YGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQNLNRDTLGFVYKLTAIKKGNTHD
ECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCCCHHHHEEEEEEECCCCCCC
VTKSPITDPTKQSIGGRFDNPNLIQVYG
CCCCCCCCCHHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure
MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFVNHEFAKK
CCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
IILEVFGNFCDSVLAVQNDPGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCC
PLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYFETVLLENILYQTTLTVAQSLK
CEEEEEECCCCCCEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAAKS
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEHHHHHHH
ILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQR
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
QEKLYLRPDSGNFETLICQGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIV
HHCEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
YGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQNLNRDTLGFVYKLTAIKKGNTHD
ECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCCCHHHHEEEEEEECCCCCCC
VTKSPITDPTKQSIGGRFDNPNLIQVYG
CCCCCCCCCHHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]