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The map label for this gene is yabD [C]

Identifier: 13507748

GI number: 13507748

Start: 11275

End: 12060

Strand: Direct

Name: yabD [C]

Synonym: MPN009

Alternate gene names: 13507748

Gene position: 11275-12060 (Clockwise)

Preceding gene: 13507747

Following gene: 13507749

Centisome position: 1.38

GC content: 39.69

Gene sequence:

>786_bases
ATGGAATACTTTGATGCGCACTGTCACTTAAACTGTGAACCCCTACTGGAACAGCACGAAAAGAGTTTGGCCAACTTTAG
GTTAATTGGGTTAAAGGCCAATGTTGTGGGCACTAATTTAACTAACTCCCAAATTGCGGTGAATTTAGCTAAACAGCACC
CTGATTTACTCAAGGCAGGGGTGGGTATTCACCCTAATGATGTCCAGCTTTTTGATTTAAAAGCAGCGCAAGCAACACTA
AAAAAATTAGTAAGTACGCATCGCTCATTCATTAGTTGTATTGGTGAATATGGCTTTGATTACCACTACACTAAGGACTA
CATTACCCAACAAGAACAGTTCTTTTTGATGCAGTTCCAACTAGCAGAACAGTACCAGTTAGTGCACATGTTGCATGTCC
GTGATGTGCACGAAAGGATATACGAAGTTTTGAAAAGGTTAAAACCTAAACAACCAGTGGTGTTTCACTGTTTTAGTGAA
GACACCAATACTGCTTTAAAGCTGCTAACTTTAAGAGAAGTAGGACTAAAGGTTTATTTTTCGATTCCGGGGATTGTGAC
CTTTAAGAATGCGAAAAACTTGCAAGCCGCTTTATCAGTTATTCCAACAGAGCTACTTTTAAGTGAAACCGATTCGCCTT
ATTTAGCACCAGTACCTTTTCGGGGCAAAACTAATTGACCGGAATGCGTTGTTCATACAGTGCAAACGATTGCTGACATT
AAGCAAGTTCCTTTAGCTGAAATAAAACAAGCGATTGTGCATAACGCCAAGAAGTTATTTTGGTAG

Upstream 100 bases:

>100_bases
ATTTACGTGCTGCTCACGAATACATTCTCCAAGTCTTGGGTAAAAACACCAACTATGACCTGATTAACGAAATCTTTAAG
CACTTTTGCTTAGGTAAGTA

Downstream 100 bases:

>100_bases
TCCTTAGGATTAACTTTTAAAAGTTCTTCTTTTGTTGGAACCTTTTCACAACTTATTCAATTTATTTAGTGTAGACATGA
ATAAAAATGCATACACTAGA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAGVGIHPNDVQLFDLKAAQATL
KKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQLAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSE
DTNTALKLLTLREVGLKVYFSIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTNWPECVVHTVQTIADI
KQVPLAEIKQAIVHNAKKLFW

Sequences:

>Translated_261_residues
MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAGVGIHPNDVQLFDLKAAQATL
KKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQLAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSE
DTNTALKLLTLREVGLKVYFSIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTN*PECVVHTVQTIADI
KQVPLAEIKQAIVHNAKKLFW
>Mature_261_residues
MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAGVGIHPNDVQLFDLKAAQATL
KKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQLAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSE
DTNTALKLLTLREVGLKVYFSIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTN*PECVVHTVQTIADI
KQVPLAEIKQAIVHNAKKLFW

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=273, Percent_Identity=26.007326007326, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=33.206106870229, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI48994985, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=26.7175572519084, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=27.3408239700375, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559024, Length=192, Percent_Identity=30.7291666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543026, Length=296, Percent_Identity=26.3513513513513, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565396, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24648690, Length=190, Percent_Identity=27.3684210526316, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29616; Mature: 29616

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAG
CCCCCCEECCCCHHHHHHHHHHHHCEEEEEEEEEEEECCCCCCCEEEEEHHHCHHHHHHC
VGIHPNDVQLFDLKAAQATLKKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQ
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
LAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSEDTNTALKLLTLREVGLKVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEE
SIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTNPECVVHTVQTIADIK
ECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHH
QVPLAEIKQAIVHNAKKLFW
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAG
CCCCCCEECCCCHHHHHHHHHHHHCEEEEEEEEEEEECCCCCCCEEEEEHHHCHHHHHHC
VGIHPNDVQLFDLKAAQATLKKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQ
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
LAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSEDTNTALKLLTLREVGLKVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEE
SIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTNPECVVHTVQTIADIK
ECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHH
QVPLAEIKQAIVHNAKKLFW
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]