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The map label for this gene is hsdS [C]

Identifier: 15669726

GI number: 15669726

Start: 1507565

End: 1508842

Strand: Direct

Name: hsdS [C]

Synonym: MJ1531

Alternate gene names: 15669726

Gene position: 1507565-1508842 (Clockwise)

Preceding gene: 15669725

Following gene: 15669727

Centisome position: 90.55

GC content: 27.93

Gene sequence:

>1278_bases
GTGGTGATTCTATTGCAATTTTATAAAGAGGAGAATTTTAAAAAAACAGAGATTGGAGAGATTCCAGAGGATTGGGAGGT
TAGGGAATTAAAAGACATTTTAGAGGTTATCAGAAATGGACTAACTGCTAAGCAAAATAAAGATAAAATAGGTTATCCAA
TAACAAGAATTGAAACGATTTCTGATAGTAAAATAGACATAACAAAATTAGGGTATGTTGAAGATATTAAACAAGAGGAT
ATTGCTAAATATAGATTAATTATCGGGGATATTTTATTCAGTCATATAAATAGTGAGGAACATATTGGAAAAGTAGCAAT
TTATGAAGGGAAACCCGAATTTTTACTTCATGGAATGAATTTACTACTTCTTAGACCTAACAAAAACAAAATTGAGCCTT
ATTATTTATTATATTTATTGAGGCATTTTAAACAAAAAAATATATTTAAATATATAGCAAAAAGAGCAGTTAATCAATCA
TCAATAAATCAAACACAACTAAAACATTTAAAAATCCCCCTCCCTCCCTTAGAAGAACAGAAACAAATAGCAAAAATATT
AAGTGACTTTGATAACCTAATAGGAACAATAAATAAGCAGATTGAAGTATTAAATAAGGCAAAAAAGGGGATGATGAAAA
AATTATTTACTAAAGGAGTTTTTGAGCATAAAAGTTTTAAAAAATCTGAAATTGGGGAGATTCCAGAGGATTGGGAGGTT
GTTGAGTTAGGAAATGAAAAATATTTCAAAATTATAATGGGACAATCACCACCATCATCATCCTATAATAAAGAAGGTGA
AGGAGTTCCATTTTTACAAGGAAAAGCAGAATTTGGAAATATTTATCCTAATCCAGTATTATACACAAATAAACCTTTAA
AAGTCGTTGATGATGAAGATATTTTAATTTCAGTTAGGGCTCCAGTTGGAGATGTAAATATAGCACCGTTTAAACTTTGT
ATCGGTAGAGGATTAGCAGGAATAAAATCAAATAAAGAAAAAGTAGATAATTTCTTTGTATTTTATTATTTGAGTTATAT
AAAGCCAAAAATAGAATATTTAGGAGGAGGTGCAGTATTCAAAGCAATAACTAAAAAAGATTTAGAAAGTATAAAAATCC
CCCTCCCACCATTAGAAGAACAAAAAGCAATAGCTAAAAGATTAAAAGCCATTGATGATTTAATAGAAATAAAAAGAAAA
GAAAAAGAACAAATAGAAAAAGCAAAAAAGAAAATAATGAATCTACTACTAACTGGAAAAATAAGAGTAAAAACCTAA

Upstream 100 bases:

>100_bases
GAGATAGAAAGCTTCTTCCAAAATACTATGAAGATGGGGAAGACGCCATATTGATGATAAAAAAGAAACCAAATGCTAAA
GGGCCATTAATAATAACGTT

Downstream 100 bases:

>100_bases
ACAATATCATTACTTATTCATATAGGTGATTTAAATGATAATAATCCCTGCAGTTGATTTAAAAGATAAAAAGTGCGTTC
AGCTAATTCAAGGAGACCCA

Product: type I restriction-modification enzyme subunit S

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVILLQFYKEENFKKTEIGEIPEDWEVRELKDILEVIRNGLTAKQNKDKIGYPITRIETISDSKIDITKLGYVEDIKQED
IAKYRLIIGDILFSHINSEEHIGKVAIYEGKPEFLLHGMNLLLLRPNKNKIEPYYLLYLLRHFKQKNIFKYIAKRAVNQS
SINQTQLKHLKIPLPPLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEV
VELGNEKYFKIIMGQSPPSSSYNKEGEGVPFLQGKAEFGNIYPNPVLYTNKPLKVVDDEDILISVRAPVGDVNIAPFKLC
IGRGLAGIKSNKEKVDNFFVFYYLSYIKPKIEYLGGGAVFKAITKKDLESIKIPLPPLEEQKAIAKRLKAIDDLIEIKRK
EKEQIEKAKKKIMNLLLTGKIRVKT

Sequences:

>Translated_425_residues
MVILLQFYKEENFKKTEIGEIPEDWEVRELKDILEVIRNGLTAKQNKDKIGYPITRIETISDSKIDITKLGYVEDIKQED
IAKYRLIIGDILFSHINSEEHIGKVAIYEGKPEFLLHGMNLLLLRPNKNKIEPYYLLYLLRHFKQKNIFKYIAKRAVNQS
SINQTQLKHLKIPLPPLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEV
VELGNEKYFKIIMGQSPPSSSYNKEGEGVPFLQGKAEFGNIYPNPVLYTNKPLKVVDDEDILISVRAPVGDVNIAPFKLC
IGRGLAGIKSNKEKVDNFFVFYYLSYIKPKIEYLGGGAVFKAITKKDLESIKIPLPPLEEQKAIAKRLKAIDDLIEIKRK
EKEQIEKAKKKIMNLLLTGKIRVKT
>Mature_425_residues
MVILLQFYKEENFKKTEIGEIPEDWEVRELKDILEVIRNGLTAKQNKDKIGYPITRIETISDSKIDITKLGYVEDIKQED
IAKYRLIIGDILFSHINSEEHIGKVAIYEGKPEFLLHGMNLLLLRPNKNKIEPYYLLYLLRHFKQKNIFKYIAKRAVNQS
SINQTQLKHLKIPLPPLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEV
VELGNEKYFKIIMGQSPPSSSYNKEGEGVPFLQGKAEFGNIYPNPVLYTNKPLKVVDDEDILISVRAPVGDVNIAPFKLC
IGRGLAGIKSNKEKVDNFFVFYYLSYIKPKIEYLGGGAVFKAITKKDLESIKIPLPPLEEQKAIAKRLKAIDDLIEIKRK
EKEQIEKAKKKIMNLLLTGKIRVKT

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0130 and MJ1218

Homologues:

Organism=Escherichia coli, GI1790807, Length=195, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1531_METJA (Q58926)

Other databases:

- EMBL:   L77117
- PIR:   B64491
- RefSeq:   NP_248539.1
- ProteinModelPortal:   Q58926
- REBASE:   3899
- GeneID:   1452439
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1531
- NMPDR:   fig|243232.1.peg.1576
- TIGR:   MJ1531
- HOGENOM:   HBG538952
- OMA:   TRYGEIP
- ProtClustDB:   CLSK796777
- BioCyc:   MJAN243232:MJ_1531-MONOMER
- InterPro:   IPR000055

Pfam domain/function: PF01420 Methylase_S

EC number: NA

Molecular weight: Translated: 48890; Mature: 48890

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILLQFYKEENFKKTEIGEIPEDWEVRELKDILEVIRNGLTAKQNKDKIGYPITRIETI
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
SDSKIDITKLGYVEDIKQEDIAKYRLIIGDILFSHINSEEHIGKVAIYEGKPEFLLHGMN
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCHHHEEECCE
LLLLRPNKNKIEPYYLLYLLRHFKQKNIFKYIAKRAVNQSSINQTQLKHLKIPLPPLEEQ
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCHHH
KQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
VELGNEKYFKIIMGQSPPSSSYNKEGEGVPFLQGKAEFGNIYPNPVLYTNKPLKVVDDED
EEECCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCEEECCCC
ILISVRAPVGDVNIAPFKLCIGRGLAGIKSNKEKVDNFFVFYYLSYIKPKIEYLGGGAVF
EEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
KAITKKDLESIKIPLPPLEEQKAIAKRLKAIDDLIEIKRKEKEQIEKAKKKIMNLLLTGK
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
IRVKT
EEECC
>Mature Secondary Structure
MVILLQFYKEENFKKTEIGEIPEDWEVRELKDILEVIRNGLTAKQNKDKIGYPITRIETI
CEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
SDSKIDITKLGYVEDIKQEDIAKYRLIIGDILFSHINSEEHIGKVAIYEGKPEFLLHGMN
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCHHHEEECCE
LLLLRPNKNKIEPYYLLYLLRHFKQKNIFKYIAKRAVNQSSINQTQLKHLKIPLPPLEEQ
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCHHH
KQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEE
VELGNEKYFKIIMGQSPPSSSYNKEGEGVPFLQGKAEFGNIYPNPVLYTNKPLKVVDDED
EEECCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCEEECCCC
ILISVRAPVGDVNIAPFKLCIGRGLAGIKSNKEKVDNFFVFYYLSYIKPKIEYLGGGAVF
EEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
KAITKKDLESIKIPLPPLEEQKAIAKRLKAIDDLIEIKRKEKEQIEKAKKKIMNLLLTGK
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
IRVKT
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087