Click here to switch to the map view.

The map label for this gene is srmB [C]

Identifier: 15669699

GI number: 15669699

Start: 1476244

End: 1478580

Strand: Reverse

Name: srmB [C]

Synonym: MJ1505

Alternate gene names: 15669699

Gene position: 1478580-1476244 (Counterclockwise)

Preceding gene: 15669700

Following gene: 15669698

Centisome position: 88.81

GC content: 30.89

Gene sequence:

>2337_bases
ATGTTTATTGAACATCCATTAATAAAACCAAAAACTTTGGAGGCGAGGTTGTATCAGCAGATTATTGCAGCAAATGCTTT
AAAGAAAAAGACATTATGTGTTTTATCGACAGGTTTAGGTAAAACAGCTATTGCTATTTTAGTTATAGCAGGTATTTTAA
CAAAAAAGGATGGAAAGGTTTTAATCTTAGCCCCTTCAAGACCTTTGGTTGAGCAACACTACAACAGATTAAAACAGGTT
TTAAACATTGATGAAGATAAAATAATAGCTTTAACTGGAAAAATCCAGCCAAAAAAGAGAGCTGAACTCTATAAAAAAGG
GAAAATCTTTATAGCTACACCACAAGTTATAGAAAACGATATCATAGCTGGAAGAATAAATGTGGATGAATTTATTTTAT
TGATAGCTGATGAAGCCCACCACACAACAGGAGACCATGCCTATGCATTTGTAGCAAAAAAATTTAAAGATAAATGTCAT
ATTTTAGGTTTAACGGCATCTCCAGGTTCTGATATTGATAAAGTCATGGAAATTTGTGAAAACTTAGGAATTGAGCACGT
TGAAGTGAGAACTGAAGATGATGAGGATGTAAAACCATACATTGCTAAAGTAAAACTTATCCCAATTAGAATTGATTTAC
CCAACGAATTTAAAAGAGCGTTAAAATTAATAAATGAAGCTTTAAAGGAGAGATTAAAAATATTAAAAGATGCTGGAGTT
ATAAATTCCATTGCCGATGTAACAAAAACAGAACTTATTGAGCTAAATAATAAGCTATTTTCCTATGATGAAGAAGTGAA
GTATGAACTTATAAAAGTTTGTTCAGAGGCTTTAAAACTTATGCATGCCAAAGAACTCTTAGAGAGTCAAGGAAAGAGTG
TATTTTTAAACTATATAAATAAATTATCCATGCAAAGAACAAAATCAGCTAAATCTATTGTTAATGATGAAAAAGTTAGA
GAGGCAGTTAATTTATTAATGAAATCAGATGTAGAACATCCAAAATTAGGTAAAGTTGTTGATATGGTTAAAAATATTTT
GGAAAAAAATAAGGATGAGAGAATTATTATCTTTGCTCAATATAGGGACACTGTAGAGAAGATTGTTAATCTCTTAACTC
AAAATGGAATTAAAGCAATAAGATTTATAGGACAGGCAAATAAAGAAGGAAAGGGAATGAGTCAGAAAGAGCAAATAGAA
GCTATAGAGAGATTTAAAAAAGAGGGAAGTGTTTTAGTTTCAACAAGCGTTTCTGAGGAGGGAATAGATATTCCATCGGT
AAATTACATCATATTTTATGAACCAGTGCCATCAGAAATTAGGTTTATTCAGAGGAGAGGTAGAGCGATGAGGGGAGAAG
GAGGGAAGGTTTATGTTTTAATAGCTAAGGGAACAGCTGATGAAGCTTATTACAGGAGTGCTTTATACAAAGAAAGGGAG
ATGAAGAGATTATTAAAAAATATGTGTTATTTGCTAAATAAGAGGTTACAGAAGAAATTTGAAGAAAAATCTAAAGAGGA
AATAAAGGAAGAGACAGAAGAAATAAAAGAAAAAGAAATTGAATCAAAAACTGCAGTAAAAGAAGAAACTAAGGAGGAAG
AAGAAAAAACCAAAAAGCCAGTAACGATATTAGATTTCATTAAACAGATTGAAGTTAAGGAAAGGTCTAAATCAGAAGAA
GATAAAATAAAACAAGAGATAAAAATTCCGAAAAAGCCAATAAAGATTATTGTAGATGTTAGAGAGAAGAATATGGCTAA
GCTTTTACATAATTATGCAAATATTGAGCTAAAAACATTAGAAGTGGGAGATTATGTTTTAAGTGATAGGGTAGTTGTTG
AGAGAAAGACAGCTGAAGACTTTGTAAATTCAATAATTGATAAGAGGTTATTTAGCCAATTAAAAAATCTTAAAAAAGTT
GAAAAACCTCTGTTAATAGTTGAAGGTGAAAACTTTAGTAGATTACATGAAAATGCACTTAAAGGGGCTATTTTATCAAT
AATTTTGGATTTTGGCATCCCAATAATATTTACAAAAAATGCTGAAGAAACAGCTGATTTATTAATAAAGATTGCTGAGA
AAGAGCAAATAAAAGAGAAAAGAACAGTTATGGTAAGGTATGGAAAGACAGCAATGTCCTTAAAAGAACAACAGAAATTT
ATTGTTGAGAGTTTGCCAGACGTTGGTGGAGCATTAGCTGAGAGGTTGTTAAAGCACTTTAAAACAGTTGAAAATGTATT
TACAGCAAAAGAAGAGGAATTAATGAAAGTTGAAGGAGTCGGAAAAGAGAGAGCTAAAAAGATTAGAGAGGTTTTAACAG
CAGAATATGAGGGATAA

Upstream 100 bases:

>100_bases
TTCTAATGTCATATGCAAACACAAAAGTTCTATTAGATACTAAAAACTATTTTTTGCTACTTTTATAATTTTTAAAGAAC
AATTGAAGAGTAGGATAACT

Downstream 100 bases:

>100_bases
AAATGAAACTCTCTATTATCTTAGGGACAAGACCTGAAATTATAAAACTTTCTCCTATAATTAGAGCTTTAGAAAAAACT
AACATAGACTGGCATATCAT

Product: Hef nuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKVLILAPSRPLVEQHYNRLKQV
LNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIENDIIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKCH
ILGLTASPGSDIDKVMEICENLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGV
INSIADVTKTELIELNNKLFSYDEEVKYELIKVCSEALKLMHAKELLESQGKSVFLNYINKLSMQRTKSAKSIVNDEKVR
EAVNLLMKSDVEHPKLGKVVDMVKNILEKNKDERIIIFAQYRDTVEKIVNLLTQNGIKAIRFIGQANKEGKGMSQKEQIE
AIERFKKEGSVLVSTSVSEEGIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYYRSALYKERE
MKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIKEKEIESKTAVKEETKEEEEKTKKPVTILDFIKQIEVKERSKSEE
DKIKQEIKIPKKPIKIIVDVREKNMAKLLHNYANIELKTLEVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLKKV
EKPLLIVEGENFSRLHENALKGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVMVRYGKTAMSLKEQQKF
IVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKERAKKIREVLTAEYEG

Sequences:

>Translated_778_residues
MFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKVLILAPSRPLVEQHYNRLKQV
LNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIENDIIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKCH
ILGLTASPGSDIDKVMEICENLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGV
INSIADVTKTELIELNNKLFSYDEEVKYELIKVCSEALKLMHAKELLESQGKSVFLNYINKLSMQRTKSAKSIVNDEKVR
EAVNLLMKSDVEHPKLGKVVDMVKNILEKNKDERIIIFAQYRDTVEKIVNLLTQNGIKAIRFIGQANKEGKGMSQKEQIE
AIERFKKEGSVLVSTSVSEEGIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYYRSALYKERE
MKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIKEKEIESKTAVKEETKEEEEKTKKPVTILDFIKQIEVKERSKSEE
DKIKQEIKIPKKPIKIIVDVREKNMAKLLHNYANIELKTLEVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLKKV
EKPLLIVEGENFSRLHENALKGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVMVRYGKTAMSLKEQQKF
IVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKERAKKIREVLTAEYEG
>Mature_778_residues
MFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKVLILAPSRPLVEQHYNRLKQV
LNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIENDIIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKCH
ILGLTASPGSDIDKVMEICENLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGV
INSIADVTKTELIELNNKLFSYDEEVKYELIKVCSEALKLMHAKELLESQGKSVFLNYINKLSMQRTKSAKSIVNDEKVR
EAVNLLMKSDVEHPKLGKVVDMVKNILEKNKDERIIIFAQYRDTVEKIVNLLTQNGIKAIRFIGQANKEGKGMSQKEQIE
AIERFKKEGSVLVSTSVSEEGIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYYRSALYKERE
MKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIKEKEIESKTAVKEETKEEEEKTKKPVTILDFIKQIEVKERSKSEE
DKIKQEIKIPKKPIKIIVDVREKNMAKLLHNYANIELKTLEVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLKKV
EKPLLIVEGENFSRLHENALKGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVMVRYGKTAMSLKEQQKF
IVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKERAKKIREVLTAEYEG

Specific function: RNA-Dependent ATPase Activity. Suppressor Of A Mutant Defective In 50s Ribosomal Subunit Assembly. Probably Interacts With 23s Ribosomal RNA. [C]

COG id: COG1111

COG function: function code L; ERCC4-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Homo sapiens, GI74959747, Length=537, Percent_Identity=30.9124767225326, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI27881482, Length=533, Percent_Identity=24.577861163227, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI149408122, Length=514, Percent_Identity=24.7081712062257, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI4885217, Length=357, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI27886568, Length=209, Percent_Identity=31.1004784688995, Blast_Score=74, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322192, Length=574, Percent_Identity=29.2682926829268, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI116008407, Length=596, Percent_Identity=29.1946308724832, Blast_Score=215, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1505_METJA (Q58900)

Other databases:

- EMBL:   L77117
- RefSeq:   NP_248512.1
- ProteinModelPortal:   Q58900
- GeneID:   1452412
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1505
- NMPDR:   fig|243232.1.peg.1549
- TIGR:   MJ1505
- HOGENOM:   HBG321504
- OMA:   FYEPVPS
- ProtClustDB:   PRK13766
- BioCyc:   MJAN243232:MJ_1505-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994
- Gene3D:   G3DSA:3.40.50.10130
- SMART:   SM00487
- SMART:   SM00891
- SMART:   SM00490
- SMART:   SM00278

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH; SSF52980 Restrict_endonuc_II-like_core; SSF47781 RuvA_2_like

EC number: =3.6.4.13

Molecular weight: Translated: 88884; Mature: 88884

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS00690 DEAH_ATP_HELICASE; PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCE
LILAPSRPLVEQHYNRLKQVLNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIEND
EEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCHHHHCC
IIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKCHILGLTASPGSDIDKVMEICE
CEEEEECHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHH
NLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGV
HCCCCEEEEECCCCCCCCHHEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCH
INSIADVTKTELIELNNKLFSYDEEVKYELIKVCSEALKLMHAKELLESQGKSVFLNYIN
HHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLSMQRTKSAKSIVNDEKVREAVNLLMKSDVEHPKLGKVVDMVKNILEKNKDERIIIFAQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEH
YRDTVEKIVNLLTQNGIKAIRFIGQANKEGKGMSQKEQIEAIERFKKEGSVLVSTSVSEE
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
GIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYYRSALYKERE
CCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
MKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIKEKEIESKTAVKEETKEEEEKTKKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTILDFIKQIEVKERSKSEEDKIKQEIKIPKKPIKIIVDVREKNMAKLLHNYANIELKTL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCEEEEE
EVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLKKVEKPLLIVEGENFSRLHENAL
EECCHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
KGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVMVRYGKTAMSLKEQQKF
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHH
IVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKERAKKIREVLTAEYEG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFIEHPLIKPKTLEARLYQQIIAANALKKKTLCVLSTGLGKTAIAILVIAGILTKKDGKV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCE
LILAPSRPLVEQHYNRLKQVLNIDEDKIIALTGKIQPKKRAELYKKGKIFIATPQVIEND
EEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCHHHHCC
IIAGRINVDEFILLIADEAHHTTGDHAYAFVAKKFKDKCHILGLTASPGSDIDKVMEICE
CEEEEECHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHH
NLGIEHVEVRTEDDEDVKPYIAKVKLIPIRIDLPNEFKRALKLINEALKERLKILKDAGV
HCCCCEEEEECCCCCCCCHHEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCH
INSIADVTKTELIELNNKLFSYDEEVKYELIKVCSEALKLMHAKELLESQGKSVFLNYIN
HHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLSMQRTKSAKSIVNDEKVREAVNLLMKSDVEHPKLGKVVDMVKNILEKNKDERIIIFAQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEH
YRDTVEKIVNLLTQNGIKAIRFIGQANKEGKGMSQKEQIEAIERFKKEGSVLVSTSVSEE
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
GIDIPSVNYIIFYEPVPSEIRFIQRRGRAMRGEGGKVYVLIAKGTADEAYYRSALYKERE
CCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
MKRLLKNMCYLLNKRLQKKFEEKSKEEIKEETEEIKEKEIESKTAVKEETKEEEEKTKKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTILDFIKQIEVKERSKSEEDKIKQEIKIPKKPIKIIVDVREKNMAKLLHNYANIELKTL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCEEEEE
EVGDYVLSDRVVVERKTAEDFVNSIIDKRLFSQLKNLKKVEKPLLIVEGENFSRLHENAL
EECCHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
KGAILSIILDFGIPIIFTKNAEETADLLIKIAEKEQIKEKRTVMVRYGKTAMSLKEQQKF
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHH
IVESLPDVGGALAERLLKHFKTVENVFTAKEEELMKVEGVGKERAKKIREVLTAEYEG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087