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The map label for this gene is yfbQ [C]

Identifier: 15669671

GI number: 15669671

Start: 1449703

End: 1451001

Strand: Direct

Name: yfbQ [C]

Synonym: MJ1479

Alternate gene names: 15669671

Gene position: 1449703-1451001 (Clockwise)

Preceding gene: 15669669

Following gene: 15669673

Centisome position: 87.07

GC content: 33.56

Gene sequence:

>1299_bases
ATGAGGAATCCTATAATAGATGTAGGGGCTAAAGAATTGAGTTATGAAATTAGGGAGATTGTAGATGTAGCTAAAAAAAT
AGAAGAGTTTGGAATAAACATAACATGGGAAAACATAGGAGACCCAGTGGCTAAAGGGGAAAAAATTCCAGATTGGATTA
AAGATATTATAGCAGAGATTGTTAAAAACGACTGTTCTTATGCCTACTGTCCTACTAAAGGTTTATTAGAAACACGAGAA
TTTTTAGCCGAACAAGTAAATAAAAGAGGAGGAGTTCAGATAACTGCTGAAGACATCATATTCTTTAACGGCTTAGGAGA
TGCCATTGCAAAGATTTATGGTTTATTGAAGAGGCAGGTTAGAGTTATAAACCCATCCCCATCATACTCAACCCATTCTT
CTGCAGAGGCATCCCATGCTGGCTCTCCTCCAGTAACTTACTTCTTAGACCCTTACAACTACTGGTATCCAGACATTGAT
GATTTGGAGAAGAGGATTAAATACAACCCAGCAGTTAGTGGAATTTTGGTTATAAATCCTGACAACCCAACTGGAGCAGT
ATATCCAAAAAAAATCTTAAATGAGATTGTTGATTTAGCCAATGAATATGATTTATTTATTATTTGTGATGAAATATACT
GTAACTTAGTATATAATGGGAAAAAACAGCATTTACTATGTGAGGTTATAGATGATGTCTGCGGTTTATCTTTAAAGGGT
ATATCAAAAGAACTTCCATGGCCAGGGGCAAGATGTGGATGGATTGAAATTTACAATGCCGATAAGGATGAAGAATTTAA
AAAATACGTTGAGAGTATTTATAAAGCCAAATTGATAGAGGTTTGCTCCACTACATTGCCACAAATGGCTATTCCAAGAA
TTATGGGGCATAGAAATTACAAAAAATACTTAGAGGAGAGGAATAGGTTCTTTGAAAAAAGGTCAAACACAGCCTACAAA
AAACTAAAAGATTTAGATGGTGTTATAGCAAATAAAGCCAATGGAGCTTTCTATATGTCTGTTGTATTTGAAGATAACTA
TTTAAATGGAAACAATTCAATAAAAATAGAGAATGAGAAATTGAAGGAATTTATAGAACACCAAATAAAAGATGCATCTA
TAGATAAGAAATTTGTTTATTATCTCTTAGCATCTACTGGAATCTGTGTAGTTCCTCTAACCTCATTCTGCTCTCAACTT
AACGGATTTAGAGTTACATTGTTAGAGAGAGATGACGAAAAGTTTGAATGGATATTTGACACATTAGCTGAAAAAATAGA
TGAATTTTTAAAGACCTAA

Upstream 100 bases:

>100_bases
ATAGAACTCTATTTTAAGAGTAAAGTTTATATACTACTGGGATAATGGTAAATTACACAAAAGTGTCATACAAAATAGAG
TTCCATTTTGAGATGAAAAC

Downstream 100 bases:

>100_bases
TCTCTCAAATGCCTATAAAACCATGGCTCTTCATAATTTTTTAAATTTTTAACATAGGGGCAGTCTTTTGGAAAAACACC
AGCTAAGATTCCTTCCATTA

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRNPIIDVGAKELSYEIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEIVKNDCSYAYCPTKGLLETRE
FLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIYGLLKRQVRVINPSPSYSTHSSAEASHAGSPPVTYFLDPYNYWYPDID
DLEKRIKYNPAVSGILVINPDNPTGAVYPKKILNEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKG
ISKELPWPGARCGWIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNYKKYLEERNRFFEKRSNTAYK
KLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEKLKEFIEHQIKDASIDKKFVYYLLASTGICVVPLTSFCSQL
NGFRVTLLERDDEKFEWIFDTLAEKIDEFLKT

Sequences:

>Translated_432_residues
MRNPIIDVGAKELSYEIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEIVKNDCSYAYCPTKGLLETRE
FLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIYGLLKRQVRVINPSPSYSTHSSAEASHAGSPPVTYFLDPYNYWYPDID
DLEKRIKYNPAVSGILVINPDNPTGAVYPKKILNEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKG
ISKELPWPGARCGWIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNYKKYLEERNRFFEKRSNTAYK
KLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEKLKEFIEHQIKDASIDKKFVYYLLASTGICVVPLTSFCSQL
NGFRVTLLERDDEKFEWIFDTLAEKIDEFLKT
>Mature_432_residues
MRNPIIDVGAKELSYEIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEIVKNDCSYAYCPTKGLLETRE
FLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIYGLLKRQVRVINPSPSYSTHSSAEASHAGSPPVTYFLDPYNYWYPDID
DLEKRIKYNPAVSGILVINPDNPTGAVYPKKILNEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKG
ISKELPWPGARCGWIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNYKKYLEERNRFFEKRSNTAYK
KLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEKLKEFIEHQIKDASIDKKFVYYLLASTGICVVPLTSFCSQL
NGFRVTLLERDDEKFEWIFDTLAEKIDEFLKT

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI4507369, Length=390, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI19263340, Length=486, Percent_Identity=23.4567901234568, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI215599424, Length=427, Percent_Identity=24.824355971897, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4885351, Length=462, Percent_Identity=24.025974025974, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788627, Length=329, Percent_Identity=32.5227963525836, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71981209, Length=489, Percent_Identity=25.7668711656442, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=312, Percent_Identity=29.1666666666667, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71981215, Length=309, Percent_Identity=26.537216828479, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=369, Percent_Identity=28.4552845528455, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=385, Percent_Identity=26.4935064935065, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551451, Length=416, Percent_Identity=26.2019230769231, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641770, Length=416, Percent_Identity=26.2019230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641760, Length=416, Percent_Identity=26.2019230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641768, Length=416, Percent_Identity=26.2019230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641766, Length=416, Percent_Identity=26.2019230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641764, Length=416, Percent_Identity=26.2019230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859735, Length=308, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1479_METJA (Q58874)

Other databases:

- EMBL:   L77117
- PIR:   F64484
- RefSeq:   NP_248484.1
- ProteinModelPortal:   Q58874
- GeneID:   1452384
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1479
- NMPDR:   fig|243232.1.peg.1521
- TIGR:   MJ1479
- HOGENOM:   HBG452053
- OMA:   YEIRNIV
- ProtClustDB:   PRK06855
- BioCyc:   MJAN243232:MJ_1479-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: 2.6.1.1

Molecular weight: Translated: 49430; Mature: 49430

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00599 AA_TRANSFER_CLASS_2; PS01048 RIBOSOMAL_S6

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNPIIDVGAKELSYEIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCCCCHHHHHHHHHHH
VKNDCSYAYCPTKGLLETREFLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIYGLLKRQV
HHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHE
RVINPSPSYSTHSSAEASHAGSPPVTYFLDPYNYWYPDIDDLEKRIKYNPAVSGILVINP
EEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEECC
DNPTGAVYPKKILNEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHEEEEECCCCHHHHHHHHHHHHCCCCCC
ISKELPWPGARCGWIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNY
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHH
KKYLEERNRFFEKRSNTAYKKLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEECCCCEEEEEHHH
LKEFIEHQIKDASIDKKFVYYLLASTGICVVPLTSFCSQLNGFRVTLLERDDEKFEWIFD
HHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCEEEEEECCCHHHHHHHH
TLAEKIDEFLKT
HHHHHHHHHHCC
>Mature Secondary Structure
MRNPIIDVGAKELSYEIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCCCCHHHHHHHHHHH
VKNDCSYAYCPTKGLLETREFLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIYGLLKRQV
HHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHE
RVINPSPSYSTHSSAEASHAGSPPVTYFLDPYNYWYPDIDDLEKRIKYNPAVSGILVINP
EEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEECC
DNPTGAVYPKKILNEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKG
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHEEEEECCCCHHHHHHHHHHHHCCCCCC
ISKELPWPGARCGWIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNY
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHH
KKYLEERNRFFEKRSNTAYKKLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEECCCCEEEEEHHH
LKEFIEHQIKDASIDKKFVYYLLASTGICVVPLTSFCSQLNGFRVTLLERDDEKFEWIFD
HHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCEEEEEECCCHHHHHHHH
TLAEKIDEFLKT
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087