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The map label for this gene is fae-hps

Identifier: 15669638

GI number: 15669638

Start: 1415835

End: 1416980

Strand: Direct

Name: fae-hps

Synonym: MJ1447

Alternate gene names: 15669638

Gene position: 1415835-1416980 (Clockwise)

Preceding gene: 15669637

Following gene: 15669639

Centisome position: 85.04

GC content: 33.51

Gene sequence:

>1146_bases
ATGATAAAATTTGGAGAAGCAGTTTTGGGAAATGAAATTAAGGCAATAGTTAATGTTGCATTAGGGAAAGGAGAGTTAAT
TGAGAATACCTTTACAAATGCTTTAACAAGAGGAAATTGTGTTTTTGCCAATTTAAGACCTAATTTAATAGTTAAACCAT
TAACCTTAGTTGTTCCAAGGCATAATATAGAGAGTGAGATACAGGATGAGCTATTTCAGGGAGTTATTCAGTATGCAGTT
GCCAAGGCAGTTGCTGATTTAGATTTAGATGAAGATTTAAAGGTTGTTGTCTCTGTTAATGTCCCAGAGGTTCCAATAAC
CAATTTAAATAAAAGAAAACTCTTCCAATACTTCTATGCCTCAGCAAAGTTAGCTATAAACAGAGCTTTAAATGAATATC
CTTCAAAAGAGAAGGTAAAGAAAGAGAAATATAGAGCTTTGCATCCATTAGTTGGATTTAGGGATGTTAGATTGGAGTAT
CCTCCATATCTACAAATTGCTTTGGATGTCCCAACTATGGAGAATTTGGAATTTTTGTTACAAACAATTCCAAATAGCGA
CCACATCATCTTAGAGGCTGGAACACCACTAATTAAAAAGTTTGGTTTAGAGGTTATTGAAATAATGAGAGAATATTTTG
ATGGCTTTATTGTTGCTGATTTAAAAACCTTAGACACTGGAAGGGTTGAGGTAAGATTGGCATTTGAAGCAACAGCTAAT
GCAGTGGCAATAAGTGGAGTAGCACCAAAATCAACAATAATTAAAGCTATCCACGAATGTCAAAAATGTGGTTTAATCAG
CTATTTGGATATGATGAACGTCTCTGAACCTCAAAAATTATATGATTCATTAAAATTAAAGCCAGATGTTGTTATCTTGC
ATAGAGGGATTGATGAGGAGACATTTGGAATTAAAAAGGAATGGAAATTTAAGGAAAACTGCTTATTAGCAATTGCTGGA
GGAGTTGGTGTGGAGAATGTTGAAGAGCTTTTAAAAGAATATCAAATATTAATCGTTGGTAGAGCAATTACAAAATCAAA
AGACCCAGGAAGAGTAATTAGGATGTTTATAAACAAGATGGGTTATGATATAGACACTTATAGGCTTTATTTTGATGAGG
ATGAGGATATAGGGGAGGAATTATGA

Upstream 100 bases:

>100_bases
AGTTTTGATCAACCTTTTCTAAAAAGGTTGTTCGGGGAGTATATAGAGATGCGAGTGGAAAATTGTTAAATTTTAAATAA
AATAGCTACAAGGGATTAAT

Downstream 100 bases:

>100_bases
ATCTGGATGCATGGTTAGATATACAGCCAGCAAAAAAACTTTACACAATAAAAGAGGCATCAAGAATATTAACAAAAAAG
TTTGGTAAGGAAATTAAAGA

Product: bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase

Products: NA

Alternate protein names: Formaldehyde-activating enzyme; Fae; 3-hexulose-6-phosphate synthase; HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MIKFGEAVLGNEIKAIVNVALGKGELIENTFTNALTRGNCVFANLRPNLIVKPLTLVVPRHNIESEIQDELFQGVIQYAV
AKAVADLDLDEDLKVVVSVNVPEVPITNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRALHPLVGFRDVRLEY
PPYLQIALDVPTMENLEFLLQTIPNSDHIILEAGTPLIKKFGLEVIEIMREYFDGFIVADLKTLDTGRVEVRLAFEATAN
AVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSLKLKPDVVILHRGIDEETFGIKKEWKFKENCLLAIAG
GVGVENVEELLKEYQILIVGRAITKSKDPGRVIRMFINKMGYDIDTYRLYFDEDEDIGEEL

Sequences:

>Translated_381_residues
MIKFGEAVLGNEIKAIVNVALGKGELIENTFTNALTRGNCVFANLRPNLIVKPLTLVVPRHNIESEIQDELFQGVIQYAV
AKAVADLDLDEDLKVVVSVNVPEVPITNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRALHPLVGFRDVRLEY
PPYLQIALDVPTMENLEFLLQTIPNSDHIILEAGTPLIKKFGLEVIEIMREYFDGFIVADLKTLDTGRVEVRLAFEATAN
AVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSLKLKPDVVILHRGIDEETFGIKKEWKFKENCLLAIAG
GVGVENVEELLKEYQILIVGRAITKSKDPGRVIRMFINKMGYDIDTYRLYFDEDEDIGEEL
>Mature_381_residues
MIKFGEAVLGNEIKAIVNVALGKGELIENTFTNALTRGNCVFANLRPNLIVKPLTLVVPRHNIESEIQDELFQGVIQYAV
AKAVADLDLDEDLKVVVSVNVPEVPITNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRALHPLVGFRDVRLEY
PPYLQIALDVPTMENLEFLLQTIPNSDHIILEAGTPLIKKFGLEVIEIMREYFDGFIVADLKTLDTGRVEVRLAFEATAN
AVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSLKLKPDVVILHRGIDEETFGIKKEWKFKENCLLAIAG
GVGVENVEELLKEYQILIVGRAITKSKDPGRVIRMFINKMGYDIDTYRLYFDEDEDIGEEL

Specific function: Catalyzes the formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily

Homologues:

Organism=Escherichia coli, GI1790006, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FAEHP_METJA (Q58842)

Other databases:

- EMBL:   L77117
- PIR:   F64480
- RefSeq:   NP_248451.1
- ProteinModelPortal:   Q58842
- SMR:   Q58842
- GeneID:   1452351
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1447
- NMPDR:   fig|243232.1.peg.1488
- TIGR:   MJ1447
- HOGENOM:   HBG541183
- OMA:   YNYGATK
- ProtClustDB:   PRK13307
- BioCyc:   MJAN243232:MJ_1447-MONOMER
- HAMAP:   MF_01268
- InterPro:   IPR013785
- InterPro:   IPR014826
- InterPro:   IPR001754
- InterPro:   IPR020568
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:3.30.230.60
- SMART:   SM00934

Pfam domain/function: PF08714 Fae; PF00215 OMPdecase; SSF54211 Ribosomal_S5_D2-typ_fold; SSF51366 RibP_bind_barrel

EC number: =4.1.2.43

Molecular weight: Translated: 42991; Mature: 42991

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKFGEAVLGNEIKAIVNVALGKGELIENTFTNALTRGNCVFANLRPNLIVKPLTLVVPR
CCCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCEEEEEEC
HNIESEIQDELFQGVIQYAVAKAVADLDLDEDLKVVVSVNVPEVPITNLNKRKLFQYFYA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
SAKLAINRALNEYPSKEKVKKEKYRALHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHH
QTIPNSDHIILEAGTPLIKKFGLEVIEIMREYFDGFIVADLKTLDTGRVEVRLAFEATAN
HHCCCCCEEEEECCCHHHHHHCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCC
AVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSLKLKPDVVILHRGIDEE
EEEEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCH
TFGIKKEWKFKENCLLAIAGGVGVENVEELLKEYQILIVGRAITKSKDPGRVIRMFINKM
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEEHHHCCCCHHHHHHHHHHHH
GYDIDTYRLYFDEDEDIGEEL
CCCEEEEEEEECCCHHCCCCC
>Mature Secondary Structure
MIKFGEAVLGNEIKAIVNVALGKGELIENTFTNALTRGNCVFANLRPNLIVKPLTLVVPR
CCCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCEEEEEEC
HNIESEIQDELFQGVIQYAVAKAVADLDLDEDLKVVVSVNVPEVPITNLNKRKLFQYFYA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
SAKLAINRALNEYPSKEKVKKEKYRALHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHH
QTIPNSDHIILEAGTPLIKKFGLEVIEIMREYFDGFIVADLKTLDTGRVEVRLAFEATAN
HHCCCCCEEEEECCCHHHHHHCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCC
AVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSLKLKPDVVILHRGIDEE
EEEEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCH
TFGIKKEWKFKENCLLAIAGGVGVENVEELLKEYQILIVGRAITKSKDPGRVIRMFINKM
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCEEEEEEEHHHCCCCHHHHHHHHHHHH
GYDIDTYRLYFDEDEDIGEEL
CCCEEEEEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087