BacMap

Definition	Methanocaldococcus jannaschii DSM 2661 chromosome, complete genome.
Accession	NC_000909
Length	1,664,970

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The map label for this gene is gabD [C]

Identifier: 15669601

GI number: 15669601

Start: 1371801

End: 1373192

Strand: Direct

Name: gabD [C]

Synonym: MJ1411

Alternate gene names: 15669601

Gene position: 1371801-1373192 (Clockwise)

Preceding gene: 15669598

Following gene: 15669602

Centisome position: 82.39

GC content: 33.55

Gene sequence:

>1392_bases
ATGTTCATAGATGGGAAGTGGATAAATAGGGAAGATATGGATGTTATTAACCCATATTCATTAGAAGTTATTAAAAAAAT
CCCTGCGTTAAGTAGGGAAGAAGCTAAAGAAGCTATAGATACGGCTGAAAAGTATAAAGAAGTTATGAAAAATCTCCCCA
TAACTAAAAGATACAACATCTTAATGAATATTGCCAAACAAATTAAAGAAAAGAAGGAAGAACTTGCCAAAATATTGGCT
ATAGATGCAGGAAAACCAATAAAACAGGCAAGAGTAGAGGTTGAAAGAAGTATTGGAACATTTAAATTAGCTGCTTTCTA
TGTTAAAGAGCATAGAGATGAGGTAATCCCTTCAGATGATAGATTAATTTTTACAAGGAGAGAACCAGTTGGAATAGTTG
GGGCTATAACACCCTTCAATTTCCCTCTAAATTTATCAGCTCATAAAATAGCCCCAGCTATAGCCACTGGGAATGTTATA
GTTCATCATCCATCATCAAAAGCTCCTCTTGTTTGTATAGAGTTGGCTAAAATCATAGAAAATGCTTTGAAGAAATATAA
TGTTCCACTGGGAGTTTATAATTTGCTAACTGGAGCTGGAGAGGTTGTAGGAGATGAGATAGTTGTTAATGAGAAGGTTA
ATATGATATCCTTCACAGGCAGTTCAAAGGTTGGAGAATTAATTACTAAAAAAGCTGGCTTTAAAAAAATTGCCTTGGAA
TTGGGAGGGGTTAATCCAAATATCGTTTTAAAAGATGCTGATTTAAATAAAGCAGTTAATGCATTAATAAAAGGCAGTTT
TATATATGCTGGACAGGTTTGCATCTCTGTAGGGATGATTTTAGTTGATGAGAGTATAGCAGATAAGTTCATAGAGATGT
TTGTAAATAAGGCAAAAGTACTTAACGTAGGAAACCCATTAGATGAGAAAACTGATGTAGGACCTTTAATAAGTGTTGAA
CATGCAGAATGGGTTGAAAAAGTTGTAGAAAAAGCTATAGATGAAGGAGGTAAGTTATTATTAGGAGGAAAGAGAGATAA
AGCTCTATTCTATCCAACAATATTGGAAGTTGATAGAGACAATATTTTATGCAAAACTGAAACATTTGCCCCAGTAATTC
CTATAATTAGAACTAATGAGGAAGAGATGATTGATATAGCCAACAGCACTGAATATGGGTTGCATTCAGCTATATTCACA
AACGATATAAATAAATCCTTAAAATTTGCTGAAAACTTGGAGTTTGGGGGAGTAGTTATAAATGATTCATCATTGTTTAG
GCAGGATAATATGCCATTTGGAGGAGTTAAGAAGAGTGGCTTAGGTAGGGAAGGAGTTAAATATGCAATGGAAGAGATGA
GCAATATAAAGACAATAATAATCTCAAAATAA

Upstream 100 bases:

>100_bases
ACACATAATATATAAACATTAAATGTTTGTTAAAAACATTTAAAATGAAAGAGGCACAAATTATAAATTAGTTACAACAT
TCTTTTTATTTGGTGGAATC

Downstream 100 bases:

>100_bases
TCTGGTGAAACTATGGCTAAGGTAATTGTAAATGGAAAGGAAAAGGTTGGAGAAACTTTAAGAGAGGTTATAAAGGATGA
ATACTATAATGAGGGAGCGA

Product: glyceraldehyde-3-phosphate dehydrogenase GapN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MFIDGKWINREDMDVINPYSLEVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNILMNIAKQIKEKKEELAKILA
IDAGKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDDRLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVI
VHHPSSKAPLVCIELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALE
LGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKVLNVGNPLDEKTDVGPLISVE
HAEWVEKVVEKAIDEGGKLLLGGKRDKALFYPTILEVDRDNILCKTETFAPVIPIIRTNEEEMIDIANSTEYGLHSAIFT
NDINKSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISK

Sequences:

>Translated_463_residues
MFIDGKWINREDMDVINPYSLEVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNILMNIAKQIKEKKEELAKILA
IDAGKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDDRLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVI
VHHPSSKAPLVCIELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALE
LGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKVLNVGNPLDEKTDVGPLISVE
HAEWVEKVVEKAIDEGGKLLLGGKRDKALFYPTILEVDRDNILCKTETFAPVIPIIRTNEEEMIDIANSTEYGLHSAIFT
NDINKSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISK
>Mature_463_residues
MFIDGKWINREDMDVINPYSLEVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNILMNIAKQIKEKKEELAKILA
IDAGKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDDRLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVI
VHHPSSKAPLVCIELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALE
LGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKVLNVGNPLDEKTDVGPLISVE
HAEWVEKVVEKAIDEGGKLLLGGKRDKALFYPTILEVDRDNILCKTETFAPVIPIIRTNEEEMIDIANSTEYGLHSAIFT
NDINKSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISK

Specific function: Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity w

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family

Homologues:

Organism=Homo sapiens, GI153266822, Length=478, Percent_Identity=36.1924686192469, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI25777730, Length=477, Percent_Identity=34.1719077568134, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=35.0104821802935, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI12007648, Length=478, Percent_Identity=33.4728033472803, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI25777732, Length=477, Percent_Identity=33.1236897274633, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI25777728, Length=417, Percent_Identity=37.1702637889688, Blast_Score=261, Evalue=8e-70,
Organism=Homo sapiens, GI21361176, Length=477, Percent_Identity=32.7044025157233, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI21614513, Length=420, Percent_Identity=35.4761904761905, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI115387104, Length=461, Percent_Identity=33.1887201735358, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI238814322, Length=482, Percent_Identity=32.7800829875519, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI25777726, Length=477, Percent_Identity=31.8658280922432, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI4507229, Length=435, Percent_Identity=34.2528735632184, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI25952152, Length=468, Percent_Identity=31.1965811965812, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI301500698, Length=475, Percent_Identity=28.4210526315789, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI11095441, Length=438, Percent_Identity=29.4520547945205, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI188035924, Length=471, Percent_Identity=28.8747346072187, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI310128093, Length=453, Percent_Identity=29.5805739514349, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI310128103, Length=453, Percent_Identity=29.3598233995585, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI310128091, Length=408, Percent_Identity=30.1470588235294, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI206597441, Length=440, Percent_Identity=29.5454545454545, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI206597439, Length=440, Percent_Identity=29.5454545454545, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI22907049, Length=440, Percent_Identity=29.5454545454545, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI4502043, Length=438, Percent_Identity=26.027397260274, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI238814371, Length=438, Percent_Identity=26.027397260274, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310128089, Length=284, Percent_Identity=32.3943661971831, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310128087, Length=449, Percent_Identity=24.9443207126949, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4557303, Length=345, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI73466520, Length=345, Percent_Identity=26.9565217391304, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI71773324, Length=345, Percent_Identity=26.0869565217391, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI238859541, Length=436, Percent_Identity=27.7522935779816, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI25777736, Length=436, Percent_Identity=27.7522935779816, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI25777734, Length=436, Percent_Identity=27.7522935779816, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI310128097, Length=244, Percent_Identity=33.6065573770492, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI310128095, Length=298, Percent_Identity=30.8724832214765, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI73695881, Length=350, Percent_Identity=25.4285714285714, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI73695879, Length=350, Percent_Identity=25.4285714285714, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI223972651, Length=457, Percent_Identity=22.7571115973742, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI310128099, Length=228, Percent_Identity=26.7543859649123, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310128101, Length=228, Percent_Identity=26.7543859649123, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1789015, Length=474, Percent_Identity=34.5991561181435, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1787684, Length=478, Percent_Identity=35.3556485355649, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1787558, Length=419, Percent_Identity=36.2768496420048, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI87081896, Length=482, Percent_Identity=30.0829875518672, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87082295, Length=483, Percent_Identity=29.8136645962733, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87081926, Length=458, Percent_Identity=32.9694323144105, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787715, Length=479, Percent_Identity=30.6889352818372, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1786504, Length=478, Percent_Identity=28.8702928870293, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788042, Length=466, Percent_Identity=27.8969957081545, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1787250, Length=450, Percent_Identity=26.8888888888889, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787653, Length=397, Percent_Identity=23.9294710327456, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788797, Length=409, Percent_Identity=23.4718826405868, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI133930964, Length=484, Percent_Identity=34.7107438016529, Blast_Score=268, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17562198, Length=473, Percent_Identity=34.46088794926, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI25144435, Length=462, Percent_Identity=32.6839826839827, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI32564736, Length=417, Percent_Identity=34.7721822541966, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17534119, Length=470, Percent_Identity=32.7659574468085, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI25143874, Length=466, Percent_Identity=32.1888412017167, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI25143876, Length=466, Percent_Identity=32.1888412017167, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71995606, Length=485, Percent_Identity=32.9896907216495, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17551164, Length=466, Percent_Identity=31.1158798283262, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI115534176, Length=420, Percent_Identity=31.1904761904762, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=33.2541567695962, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71986308, Length=459, Percent_Identity=28.9760348583878, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25146391, Length=441, Percent_Identity=27.2108843537415, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI32566756, Length=441, Percent_Identity=27.2108843537415, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25146394, Length=441, Percent_Identity=27.2108843537415, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17564084, Length=431, Percent_Identity=28.538283062645, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534447, Length=455, Percent_Identity=26.1538461538462, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564151, Length=422, Percent_Identity=26.303317535545, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115532534, Length=397, Percent_Identity=26.448362720403, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990744, Length=307, Percent_Identity=26.3843648208469, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319478, Length=477, Percent_Identity=34.5911949685535, Blast_Score=259, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6324950, Length=472, Percent_Identity=34.9576271186441, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6320917, Length=474, Percent_Identity=32.9113924050633, Blast_Score=249, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6325196, Length=479, Percent_Identity=32.3590814196242, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6323821, Length=486, Percent_Identity=31.8930041152263, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323822, Length=469, Percent_Identity=31.9829424307036, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321828, Length=483, Percent_Identity=25.0517598343685, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321826, Length=431, Percent_Identity=27.6102088167053, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323757, Length=347, Percent_Identity=31.1239193083574, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129399, Length=478, Percent_Identity=33.0543933054393, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24585660, Length=484, Percent_Identity=31.8181818181818, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281362580, Length=477, Percent_Identity=33.5429769392034, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI62472918, Length=477, Percent_Identity=33.5429769392034, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI62472926, Length=477, Percent_Identity=33.5429769392034, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI62472936, Length=477, Percent_Identity=33.5429769392034, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI21356737, Length=477, Percent_Identity=33.5429769392034, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24650465, Length=442, Percent_Identity=34.6153846153846, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24666674, Length=474, Percent_Identity=30.168776371308, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24638878, Length=471, Percent_Identity=27.3885350318471, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24638876, Length=471, Percent_Identity=27.3885350318471, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281360301, Length=424, Percent_Identity=27.5943396226415, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360299, Length=424, Percent_Identity=27.5943396226415, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360297, Length=424, Percent_Identity=27.5943396226415, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360295, Length=424, Percent_Identity=27.5943396226415, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24586250, Length=424, Percent_Identity=27.5943396226415, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360303, Length=425, Percent_Identity=27.7647058823529, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45552499, Length=425, Percent_Identity=27.7647058823529, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24668425, Length=432, Percent_Identity=26.3888888888889, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24668417, Length=432, Percent_Identity=26.3888888888889, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24668413, Length=432, Percent_Identity=26.3888888888889, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574525, Length=473, Percent_Identity=22.8329809725159, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI28571798, Length=465, Percent_Identity=25.1612903225806, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571796, Length=465, Percent_Identity=25.1612903225806, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571794, Length=465, Percent_Identity=25.1612903225806, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571806, Length=465, Percent_Identity=25.1612903225806, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571802, Length=465, Percent_Identity=25.1612903225806, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571800, Length=465, Percent_Identity=25.1612903225806, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360293, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LADH_METJA (Q58806)

Other databases:

- EMBL:   L77117
- PIR:   B64476
- RefSeq:   NP_248414.1
- ProteinModelPortal:   Q58806
- SMR:   Q58806
- GeneID:   1452314
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1411
- NMPDR:   fig|243232.1.peg.1451
- TIGR:   MJ1411
- HOGENOM:   HBG752218
- OMA:   ITKKAGF
- ProtClustDB:   CLSK876565
- BioCyc:   MetaCyc:MONOMER-12177
- BioCyc:   MJAN243232:MJ_1411-MONOMER
- BRENDA:   1.2.1.22
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.22

Molecular weight: Translated: 51136; Mature: 51136

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 240-240 ACT_SITE 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDGKWINREDMDVINPYSLEVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNI
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LMNIAKQIKEKKEELAKILAIDAGKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
RLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVCIELAKIIE
CEEEEECCCCEEEEEECCCCCCCCCCHHHHCCEEEECCEEEECCCCCCCCHHHHHHHHHH
NALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALE
HHHHHCCCCHHHHHHHHCCCHHCCCEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEE
LGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKV
ECCCCCCEEEECCCHHHHHHHHHCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHCCHHE
LNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGKRDKALFYPTILEVDRD
EECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCEEEEECCC
NILCKTETFAPVIPIIRTNEEEMIDIANSTEYGLHSAIFTNDINKSLKFAENLEFGGVVI
CEEEEECCCCCCCCEEECCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISK
CCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
>Mature Secondary Structure
MFIDGKWINREDMDVINPYSLEVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNI
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LMNIAKQIKEKKEELAKILAIDAGKPIKQARVEVERSIGTFKLAAFYVKEHRDEVIPSDD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
RLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVCIELAKIIE
CEEEEECCCCEEEEEECCCCCCCCCCHHHHCCEEEECCEEEECCCCCCCCHHHHHHHHHH
NALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALE
HHHHHCCCCHHHHHHHHCCCHHCCCEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEE
LGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKV
ECCCCCCEEEECCCHHHHHHHHHCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHCCHHE
LNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGKRDKALFYPTILEVDRD
EECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCEEEEECCC
NILCKTETFAPVIPIIRTNEEEMIDIANSTEYGLHSAIFTNDINKSLKFAENLEFGGVVI
CEEEEECCCCCCCCEEECCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISK
CCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087