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The map label for this gene is queC [H]

Identifier: 15669538

GI number: 15669538

Start: 1294372

End: 1295079

Strand: Direct

Name: queC [H]

Synonym: MJ1347

Alternate gene names: 15669538

Gene position: 1294372-1295079 (Clockwise)

Preceding gene: 15669537

Following gene: 15669539

Centisome position: 77.74

GC content: 34.89

Gene sequence:

>708_bases
GTGATTATTATGAAGGCAATAACTGTTTTAAGTGGTGGATTAGATTCTACAGTAGTCACACTGATAGCTAAAGATTTAGG
TTATGAAGTTACGGCAATAACTTTTAACTATGGGCAAAGAGCGGCTAAGAGAGAGATTAATTCAGCAAAGAAGATTTGTG
AGATTTTGGGTATTGAACACATTGTTGTAGATTTACCATTCGTTAAACAGTTTGGAAAAAGCTCTTTAATAACTGAAAAG
GAAATTCCAACATTAAAAATGGAAGAGTTAGATAGTGAGAAAGCTTATGAAACAATGAAGGCTGTATGGGTTCCAGCAAG
GAATGTAATCATGTTTGGTATAGCAAGCGGATTTGCTGAGGCATTGGATGCAGAGAAGATATTCATTGGAATAAATAAAG
AGGAAGGAGTTACTTTCCCAGACAACACAATAGAATTTGTTGAGGCATTTAATAAAGTTTTGGAGTATGGAACACTAAAT
AAGGTTAAGATAGAAGCTCCTCTATATGACAAAACAAAGGAGGAGATTGTTAAATTAGGGGCTGAATTGGAGAAAAAGCT
TGGTGTTGAGGTTTTGAAATATAGTTATTCATGCTATCATGATAATGGAGAGGACTTTTTACACTGTGGGAAGTGTGAGA
GCTGTATGAGAAGGAAGAGAGCTTTTTTAATGGCTGGAGTTGAAGATAAGACAAAGTATATTGAATAG

Upstream 100 bases:

>100_bases
GTAAATACTTAATCTACTAAAATTTCTTCTCTTTTACCTTTTTTTATTACAGCAAAATTCCAAAGATTCCAATTATTTAA
TTTTAATATAATTTTAAAAG

Downstream 100 bases:

>100_bases
GAAGATTGATTCTTTAATATGTTGATTTTTTATTTTGAGATGTTTAGAGCTTAATTGGGAGATTATGAACAAAGATTCGT
CAAATTTTCTATACAAATAT

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIIMKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEHIVVDLPFVKQFGKSSLITEK
EIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAEALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLN
KVKIEAPLYDKTKEEIVKLGAELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE

Sequences:

>Translated_235_residues
MIIMKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEHIVVDLPFVKQFGKSSLITEK
EIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAEALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLN
KVKIEAPLYDKTKEEIVKLGAELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE
>Mature_235_residues
MIIMKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEHIVVDLPFVKQFGKSSLITEK
EIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAEALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLN
KVKIEAPLYDKTKEEIVKLGAELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=237, Percent_Identity=30.8016877637131, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 26387; Mature: 26387

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIMKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEH
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHH
IVVDLPFVKQFGKSSLITEKEIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAE
HEECCHHHHHCCCCCCCCCCCCCCEEHHHCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLNKVKIEAPLYDKTKEEIVKLG
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
AELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE
HHHHHHHCHHHHHHHHHEECCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MIIMKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEH
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHH
IVVDLPFVKQFGKSSLITEKEIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAE
HEECCHHHHHCCCCCCCCCCCCCCEEHHHCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLNKVKIEAPLYDKTKEEIVKLG
HHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
AELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE
HHHHHHHCHHHHHHHHHEECCCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]