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The map label for this gene is 15669536

Identifier: 15669536

GI number: 15669536

Start: 1291895

End: 1292839

Strand: Direct

Name: 15669536

Synonym: MJ1345

Alternate gene names: NA

Gene position: 1291895-1292839 (Clockwise)

Preceding gene: 15669533

Following gene: 15669537

Centisome position: 77.59

GC content: 27.51

Gene sequence:

>945_bases
TTGGGGGAGGGGGTGAATATGGAAATATATAATGAAAGCATTTTATGGGATGAATATTTTGATGCACTTGAAAAAAGAAA
TTATGAAAAAGCCCTATTATTGATAGACAAAATCTTAGAGGTTAGGGAATCTCCCGATGTTTATGTAAGAAAAGCAAGAA
TATTAAGAACATTGGGGGAAAATGATAAAGCATTAGAATATTTTGATAAAGCGTTAAAATTAAAACCAAAATATATTTTA
GCAAATTTTTTAAAAGGAGCTTTATTGGTAAGTTTGGGTAAATTAGAAGAAGCAAAAGAGGTATTCTTAAAATTATGCAG
ATTAGAAAAATCTGATTTACCTGTTAAATATGTAACTGCCTTTATACTAAAAAAACTTGGAGAGTATGATTATGCATTAA
AAATTATTGATAAAATATTGAAAAAATATCCAAAATCAGCTATTGCCTGGGCTGAAAAAGGGGAAATATTATATAGAGAA
GGCAAACTTAAAAAATCATTAGAATGTTTTGATAATGCTTTAAAAATAAATCCCAAAGATTGCCAGTCCTTATTGTACAA
AGGAGAAATATTATTTAAACTTGGAAGATATGGAGAAGCATTAAAATGTCTAAAAAAAGTTTTTGAAAGAAATAATAAAG
ATATTCGTGCATTAATGTACATAATACAAATTTTGATTTATCTTGGAAGATTAAATCAAGCCCTTGAATATACTAAAAAA
GCTTTAAAATTGAATCCAGATGACCCATTACTTTATCTATACAAGGGTATTATACTAAACAAGCTTGGAAAATATAATGA
AGCTATAAAATATTTTGATAAAGTGCTGGAAATTAACCCAAATATTCCAGATGCTTGGAATGGGAAAGCCATAGCTCTCG
AAAAACTTGGAAAAATTAATGAAGCTATAGAGTGTTACAATAGAGCACTTGATATTTATGAATAA

Upstream 100 bases:

>100_bases
ATATTTTACACTAAAATAATTTTAATAAATAATATCATAGTAATAATAATTTAACGAAATTCGTAAAATAGGGGGATTAA
AATCGCATATTGCTAAAACC

Downstream 100 bases:

>100_bases
ATTTTTATATTTTAATTTAAATTGAATATACCGTAAATTATATATATATGGAAGTAGGAAACTTACTTCCAGAATTATTC
AATCAAATTGCATTGGGGGA

Product: O-linked GlnNAc transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGENDKALEYFDKALKLKPKYIL
ANFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTAFILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYRE
GKLKKSLECFDNALKINPKDCQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKK
ALKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKINEAIECYNRALDIYE

Sequences:

>Translated_314_residues
MGEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGENDKALEYFDKALKLKPKYIL
ANFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTAFILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYRE
GKLKKSLECFDNALKINPKDCQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKK
ALKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKINEAIECYNRALDIYE
>Mature_313_residues
GEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGENDKALEYFDKALKLKPKYILA
NFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTAFILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYREG
KLKKSLECFDNALKINPKDCQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKKA
LKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKINEAIECYNRALDIYE

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats

Homologues:

Organism=Homo sapiens, GI32307150, Length=275, Percent_Identity=23.6363636363636, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32307148, Length=275, Percent_Identity=23.6363636363636, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI83415184, Length=254, Percent_Identity=25.1968503937008, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI301336134, Length=254, Percent_Identity=25.1968503937008, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI170784867, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=292, Percent_Identity=24.3150684931507, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115532692, Length=255, Percent_Identity=25.8823529411765, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17647755, Length=275, Percent_Identity=23.2727272727273, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24585827, Length=275, Percent_Identity=23.2727272727273, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24585829, Length=275, Percent_Identity=23.2727272727273, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647123, Length=271, Percent_Identity=25.0922509225092, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24659892, Length=240, Percent_Identity=25.8333333333333, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1345_METJA (Q58741)

Other databases:

- EMBL:   L77117
- PIR:   H64467
- RefSeq:   NP_248347.1
- ProteinModelPortal:   Q58741
- GeneID:   1452248
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1345
- NMPDR:   fig|243232.1.peg.1384
- TIGR:   MJ1345
- OMA:   HAGREEY
- ProtClustDB:   CLSK2517723
- BioCyc:   MJAN243232:MJ_1345-MONOMER
- GO:   GO:0005488
- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734
- Gene3D:   G3DSA:1.25.40.120
- Gene3D:   G3DSA:1.25.40.10
- SMART:   SM00028

Pfam domain/function: PF00515 TPR_1

EC number: NA

Molecular weight: Translated: 36519; Mature: 36387

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50005 TPR; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGE
CCCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
NDKALEYFDKALKLKPKYILANFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYREGKLKKSLECFDNALKINPKD
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHH
CQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKIN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
EAIECYNRALDIYE
HHHHHHHHHHCCCC
>Mature Secondary Structure 
GEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGE
CCCCCEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
NDKALEYFDKALKLKPKYILANFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYREGKLKKSLECFDNALKINPKD
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCHHH
CQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKIN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
EAIECYNRALDIYE
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413