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The map label for this gene is gmhA [H]

Identifier: 15669526

GI number: 15669526

Start: 1284335

End: 1284766

Strand: Direct

Name: gmhA [H]

Synonym: MJ1335

Alternate gene names: 15669526

Gene position: 1284335-1284766 (Clockwise)

Preceding gene: 15669523

Following gene: 15669527

Centisome position: 77.14

GC content: 36.81

Gene sequence:

>432_bases
TTGTGGAAATGGAGGAGTGCAGCTAACTCTCAGCATTTTGCCGCTGAGATTGTAGGAAGGTTTAAGTTAGAAAGGAAAGG
ATTGCCTGCAATTGCATTAACAACAGATATATCAATTTTAACAGCTATAGGAAATGATTATGGTTTTGATAGGATTTTTG
AGAGGCAAGTTGAAGCTTTGGGAAAAGAAGGAGATGTTTTGGCCGGTATATCAACAAGTGGAAATTCAGAAAACGTTATA
AAGGCAGCTAATAAAGCAAAGGAAATGGGGATTTATACAATTGGTTTATTGGGAAAAGGTGGAGGAAAGCTAAAGGATAT
TGTTGATTTGGCATTGGTGGTTCCTTCTAATGACACAGCAAGGATACAAGAGTGCCATCTAACAATTTATCATGTTATAT
GTGAGGAGGTTGAGAAAAAATTGGTGAAATAG

Upstream 100 bases:

>100_bases
CAAATGTGAAACTAAAATTCATTGAAGAAGATGAGGAAAAGTTAAAAAAAGCTATTGAAGTCATATATAATGCATTAAAA
AATGGAAATAAAATTTTAAT

Downstream 100 bases:

>100_bases
ATGATAATTGAAGATAGAGAAACGTTAAAAAAGAAGGCCAACAATAGTAAAGCATAGATTTGTTGCTATGGGTTATAATC
AGCAATTGCTTAGGGTTGAT

Product: phosphoheptose isomerase GmhA

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MWKWRSAANSQHFAAEIVGRFKLERKGLPAIALTTDISILTAIGNDYGFDRIFERQVEALGKEGDVLAGISTSGNSENVI
KAANKAKEMGIYTIGLLGKGGGKLKDIVDLALVVPSNDTARIQECHLTIYHVICEEVEKKLVK

Sequences:

>Translated_143_residues
MWKWRSAANSQHFAAEIVGRFKLERKGLPAIALTTDISILTAIGNDYGFDRIFERQVEALGKEGDVLAGISTSGNSENVI
KAANKAKEMGIYTIGLLGKGGGKLKDIVDLALVVPSNDTARIQECHLTIYHVICEEVEKKLVK
>Mature_143_residues
MWKWRSAANSQHFAAEIVGRFKLERKGLPAIALTTDISILTAIGNDYGFDRIFERQVEALGKEGDVLAGISTSGNSENVI
KAANKAKEMGIYTIGLLGKGGGKLKDIVDLALVVPSNDTARIQECHLTIYHVICEEVEKKLVK

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=139, Percent_Identity=49.6402877697842, Blast_Score=136, Evalue=5e-34,
Organism=Escherichia coli, GI1789539, Length=139, Percent_Identity=44.6043165467626, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620 [H]

Pfam domain/function: NA

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 15599; Mature: 15599

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKWRSAANSQHFAAEIVGRFKLERKGLPAIALTTDISILTAIGNDYGFDRIFERQVEAL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHEEECCCCCCHHHHHHHHHHHC
GKEGDVLAGISTSGNSENVIKAANKAKEMGIYTIGLLGKGGGKLKDIVDLALVVPSNDTA
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHEEEEEEECCCCCC
RIQECHLTIYHVICEEVEKKLVK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWKWRSAANSQHFAAEIVGRFKLERKGLPAIALTTDISILTAIGNDYGFDRIFERQVEAL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHEEECCCCCCHHHHHHHHHHHC
GKEGDVLAGISTSGNSENVIKAANKAKEMGIYTIGLLGKGGGKLKDIVDLALVVPSNDTA
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCHHHHEEEEEEECCCCCC
RIQECHLTIYHVICEEVEKKLVK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]