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The map label for this gene is map

Identifier: 15669519

GI number: 15669519

Start: 1279377

End: 1280261

Strand: Direct

Name: map

Synonym: MJ1329

Alternate gene names: 15669519

Gene position: 1279377-1280261 (Clockwise)

Preceding gene: 15669518

Following gene: 15669520

Centisome position: 76.84

GC content: 35.07

Gene sequence:

>885_bases
ATGGAGATTGAAGGGTATGAAAAGATTATAGAGGCAGGGAAAATAGCATCTAAAGTCAGAGAGGAGGCCGTAAAATTAAT
AARGCCAGGAGTTAAGCTATTAGAAGTTGCTGAATTTGTTGAAAATAGAATTAGGGAATTAGGAGGGGAGCCAGCATTTC
CGTGCAATATATCAATTAATGAGATAGCAGCTCATTACACTCCAAAATTAAATGATAACTTGGAGTTTAAAGATGATGAT
GTTGTTAAATTAGATTTAGGAGCTCATGTCGATGGATATATAGCAGATACAGCTATAACAGTAGATTTATCAAACTCTTA
TAAAGATTTGGTAAAGGCATCTGAAGATGCACTATATACAGTTATTAAGGAGATAAACCCTCCAATGAACATTGGAGAGA
TGGGAAAGATTATTCAGGAGGTTATTGAGAGTTATGGTTATAAACCAATATCCAACCTCTCTGGACATGTGATGCATAGA
TATGAGTTGCATACAGGAATTAGTATTCCAAATGTCTATGAAAGAACCAATCAATATATAGATGTTGGAGATTTGGTGGC
TATAGAGCCGTTTGCAACAGATGGCTTTGGAATGGTTAAAGATGGGAATCTTGGAAACATATATAAATTTTTAGCCAAAA
GACCAATTAGATTGCCACAAGCAAGAAAACTTTTAGACGTTATATCAAAAAATTACCCTTATCTACCCTTTGCTGAAAGA
TGGGTTTTAAAAAATGAGAGCGAGAGGCTGGCTTTAAACTCGTTAATTAGGGCATCTTGCATTTACGGTTATCCAATATT
AAAAGAGAGGGAGAATGGAATAGTTGGCCAGGCTGAGCACACAATATTAATAACTGAAAATGGTGTTGAGATAACAACAA
AATAG

Upstream 100 bases:

>100_bases
ATTGATTATATTATAGTTTCAGCAATAAATAACAATCAATTTAAAGGTTATCAAACAACACTAAAAAACTTATTAAAACC
AAAACTTAAAGGATGAAAGT

Downstream 100 bases:

>100_bases
TATAGAATATTTAAGTTTTTTAATAAAAAATGAGATTTTATTTTAATGTTTATTATAAGAGATATGCCCATAAAATCCAA
AATATTAAAGTGAGAAAATG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEIEGYEKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISINEIAAHYTPKLNDNLEFKDDD
VVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYTVIKEINPPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHR
YELHTGISIPNVYERTNQYIDVGDLVAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAER
WVLKNESERLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK

Sequences:

>Translated_294_residues
MEIEGYEKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISINEIAAHYTPKLNDNLEFKDDD
VVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYTVIKEINPPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHR
YELHTGISIPNVYERTNQYIDVGDLVAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAER
WVLKNESERLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK
>Mature_294_residues
MEIEGYEKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISINEIAAHYTPKLNDNLEFKDDD
VVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYTVIKEINPPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHR
YELHTGISIPNVYERTNQYIDVGDLVAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAER
WVLKNESERLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK

Specific function: Removes the amino-terminal methionine from nascent proteins

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family

Homologues:

Organism=Homo sapiens, GI5803092, Length=309, Percent_Identity=34.6278317152104, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI124494254, Length=255, Percent_Identity=24.3137254901961, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI164420681, Length=208, Percent_Identity=25.4807692307692, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786364, Length=304, Percent_Identity=25, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17544396, Length=313, Percent_Identity=31.629392971246, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17542840, Length=256, Percent_Identity=26.5625, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319380, Length=318, Percent_Identity=33.6477987421384, Blast_Score=167, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17137568, Length=309, Percent_Identity=32.0388349514563, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24658585, Length=310, Percent_Identity=25.4838709677419, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355531, Length=208, Percent_Identity=25.9615384615385, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): AMPM_METJA (Q58725)

Other databases:

- EMBL:   L77117
- PIR:   H64465
- RefSeq:   NP_248330.1
- ProteinModelPortal:   Q58725
- MEROPS:   M24.002
- GeneID:   1452231
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1329
- NMPDR:   fig|243232.1.peg.1367
- TIGR:   MJ1329
- HOGENOM:   HBG318153
- OMA:   IEPFATN
- ProtClustDB:   PRK08671
- BioCyc:   MJAN243232:MJ_1329-MONOMER
- BRENDA:   3.4.11.18
- GO:   GO:0006508
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002468
- InterPro:   IPR018349
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.90.230.10
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10804:SF9
- PANTHER:   PTHR10804
- PRINTS:   PR00599
- TIGRFAMs:   TIGR00501

Pfam domain/function: PF00557 Peptidase_M24; SSF55920 Peptidase_M24_cat_core

EC number: =3.4.11.18

Molecular weight: Translated: 32896; Mature: 32896

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01202 MAP_2

Important sites: BINDING 65-65 BINDING 164-164

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIEGYEKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
EIAAHYTPKLNDNLEFKDDDVVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYT
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCHHHHHHHCCHHHHHH
VIKEINPPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHRYELHTGISIPNVYERTNQYI
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHCCCEE
DVGDLVAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAER
CCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHH
WVLKNESERLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECC
>Mature Secondary Structure
MEIEGYEKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
EIAAHYTPKLNDNLEFKDDDVVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYT
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCHHHHHHHCCHHHHHH
VIKEINPPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHRYELHTGISIPNVYERTNQYI
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCCCHHHHHCCCEE
DVGDLVAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAER
CCCCEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHH
WVLKNESERLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087