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The map label for this gene is bioW

Identifier: 15669487

GI number: 15669487

Start: 1244625

End: 1245338

Strand: Direct

Name: bioW

Synonym: MJ1297

Alternate gene names: 15669487

Gene position: 1244625-1245338 (Clockwise)

Preceding gene: 15669483

Following gene: 15669488

Centisome position: 74.75

GC content: 32.77

Gene sequence:

>714_bases
TTGGTGATTGTTATGTATAGTATAAAGATGAGGGCATCGAAGAATGGAAAACACATCTCTGGAGCTGAGAGAATTGTAAA
TAAAGATGAGATTGAAGAGACTGTTAAGGAGCTTGTAAGAAGGGCTTTAACTCATGAAAATGGAACTCCAGACTTTATAA
ATATAAAGATTGAAGAGATTAAAGAAGAGATAACATACATTAACCACTTGCCAATAAAAACAATACACTGTAAAGATAAA
GAAGAGGCAAGAGAAACGGCAAAGAAAATATTAAGAAATGAAGGCATCCCAGATAGCGTTATAGATTATGCTTATGAGAT
TATTGATAAAGGGGGAATGAGAGGAGCAGCAATTTTAAATTTAAAGGGAGAGAGGTTAGAGCCAGATAAGGAGAGAGGAG
TTAGAGTTAAAAACATAGATACAACAAAGGAATTGAAAGAGAAGATTTTAAAAGAAAATTTAGGGACAGAAAGAACTGTC
GATGCCATTGCCATAGCATCTAAGGTTATTCATTTGGGAGTTATTGCAGAACTCTGCACATCGGATAATAAAAGCTACAC
AACTGGCTATGTAGCAACTAAAAAGGGATACTTTAGAATTACAAATTTAAAAAAAGAGGGAGAAAGTGGAGGAAGGGTAT
TTTTTGTTAAAGATGATGTTGATATAGAGGATTTAATCAACAAATTAGAAAACAAACCATTTATTATAAAATAA

Upstream 100 bases:

>100_bases
TCAAAATCTATTTTGTTCTTTAGAGATTTTTTTAAAAAAGTTTCAATCTCCATAAAAATCACCCTATATACAATAAATAA
ACATTAACTTTTAAAATTTA

Downstream 100 bases:

>100_bases
AAAGGGATTTTTATGTTTAGGGAGAAATTAAGAAGAGAGATTGAAATTATAAAGAACAACGGATTATATAGATTTTTAAG
GAAAAAAGATGATGGAGTTT

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVIVMYSIKMRASKNGKHISGAERIVNKDEIEETVKELVRRALTHENGTPDFINIKIEEIKEEITYINHLPIKTIHCKDK
EEARETAKKILRNEGIPDSVIDYAYEIIDKGGMRGAAILNLKGERLEPDKERGVRVKNIDTTKELKEKILKENLGTERTV
DAIAIASKVIHLGVIAELCTSDNKSYTTGYVATKKGYFRITNLKKEGESGGRVFFVKDDVDIEDLINKLENKPFIIK

Sequences:

>Translated_237_residues
MVIVMYSIKMRASKNGKHISGAERIVNKDEIEETVKELVRRALTHENGTPDFINIKIEEIKEEITYINHLPIKTIHCKDK
EEARETAKKILRNEGIPDSVIDYAYEIIDKGGMRGAAILNLKGERLEPDKERGVRVKNIDTTKELKEKILKENLGTERTV
DAIAIASKVIHLGVIAELCTSDNKSYTTGYVATKKGYFRITNLKKEGESGGRVFFVKDDVDIEDLINKLENKPFIIK
>Mature_237_residues
MVIVMYSIKMRASKNGKHISGAERIVNKDEIEETVKELVRRALTHENGTPDFINIKIEEIKEEITYINHLPIKTIHCKDK
EEARETAKKILRNEGIPDSVIDYAYEIIDKGGMRGAAILNLKGERLEPDKERGVRVKNIDTTKELKEKILKENLGTERTV
DAIAIASKVIHLGVIAELCTSDNKSYTTGYVATKKGYFRITNLKKEGESGGRVFFVKDDVDIEDLINKLENKPFIIK

Specific function: Transforms pimelate into pimeloyl-CoA

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOW_METJA (Q58693)

Other databases:

- EMBL:   L77117
- PIR:   H64461
- RefSeq:   NP_248297.1
- ProteinModelPortal:   Q58693
- GeneID:   1452199
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1297
- NMPDR:   fig|243232.1.peg.1334
- TIGR:   MJ1297
- HOGENOM:   HBG507782
- OMA:   TVDAIAI
- ProtClustDB:   PRK01322
- BioCyc:   MJAN243232:MJ_1297-MONOMER
- BRENDA:   6.2.1.14
- HAMAP:   MF_00668
- InterPro:   IPR005499
- ProDom:   PD017229
- TIGRFAMs:   TIGR01204

Pfam domain/function: PF03744 BioW

EC number: =6.2.1.14

Molecular weight: Translated: 26884; Mature: 26884

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00230 MAP1B_NEURAXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVMYSIKMRASKNGKHISGAERIVNKDEIEETVKELVRRALTHENGTPDFINIKIEEI
CEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
KEEITYINHLPIKTIHCKDKEEARETAKKILRNEGIPDSVIDYAYEIIDKGGMRGAAILN
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEE
LKGERLEPDKERGVRVKNIDTTKELKEKILKENLGTERTVDAIAIASKVIHLGVIAELCT
ECCCCCCCHHHHCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SDNKSYTTGYVATKKGYFRITNLKKEGESGGRVFFVKDDVDIEDLINKLENKPFIIK
CCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MVIVMYSIKMRASKNGKHISGAERIVNKDEIEETVKELVRRALTHENGTPDFINIKIEEI
CEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
KEEITYINHLPIKTIHCKDKEEARETAKKILRNEGIPDSVIDYAYEIIDKGGMRGAAILN
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEE
LKGERLEPDKERGVRVKNIDTTKELKEKILKENLGTERTVDAIAIASKVIHLGVIAELCT
ECCCCCCCHHHHCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SDNKSYTTGYVATKKGYFRITNLKKEGESGGRVFFVKDDVDIEDLINKLENKPFIIK
CCCCCEEEEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087