BacMap

Definition	Methanocaldococcus jannaschii DSM 2661 chromosome, complete genome.
Accession	NC_000909
Length	1,664,970

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The map label for this gene is pan

Identifier: 15669365

GI number: 15669365

Start: 1114985

End: 1116277

Strand: Reverse

Name: pan

Synonym: MJ1176

Alternate gene names: 15669365

Gene position: 1116277-1114985 (Counterclockwise)

Preceding gene: 15669366

Following gene: 15669364

Centisome position: 67.04

GC content: 35.42

Gene sequence:

>1293_bases
ATGGTTTTTGAAGAATTTATTTCAACTGAATTGAAGAAAGAAAAGAAAGCATTTACTGAAGAATTTAAAGAAGAAAAGGA
AATAAACGATAATTCTAACTTAAAAAATGATTTACTTAAAGAGGAACTCCAAGAAAAGGCAAGAATTGCAGAATTAGAAA
GTAGAATCCTAAAATTAGAATTAGAGAAAAAAGAGCTTGAAAGAGAGAATTTACAGTTAATGAAAGAAAATGAGATTTTA
AGAAGAGAATTAGATAGAATGAGAGTCCCTCCATTGATAGTTGGAACTGTAGTTGATAAAGTAGGAGAGAGAAAAGTAGT
TGTCAAAAGCTCAACAGGCCCAAGTTTCTTAGTTAATGTCTCTCACTTTGTAAATCCAGATGATTTAGCCCCTGGAAAGA
GAGTCTGTTTAAATCAGCAAACATTAACAGTTGTTGATGTATTGCCAGAAAATAAAGACTACAGAGCTAAAGCAATGGAA
GTTGATGAAAGACCAAATGTTAGATATGAAGATATTGGTGGATTAGAGAAACAAATGCAAGAAATTAGAGAAGTTGTTGA
ACTCCCATTGAAACATCCAGAATTGTTTGAAAAGGTTGGAATTGAACCACCAAAAGGTATTCTGCTTTACGGACCACCAG
GAACTGGAAAGACATTATTAGCTAAAGCTGTTGCTACAGAAACAAATGCTACCTTTATAAGAGTTGTTGGTTCTGAATTG
GTTAAGAAGTTTATTGGAGAGGGGGCTTCGTTAGTTAAAGATATATTCAAATTGGCTAAAGAAAAAGCTCCTTCAATCAT
ATTCATAGATGAGATTGATGCTATTGCAGCAAAGAGAACAGACGCTTTAACTGGTGGAGATAGGGAAGTTCAGAGAACAT
TAATGCAGTTGTTGGCAGAGATGGATGGATTCGATGCAAGGGGAGATGTTAAGATAATTGGGGCCACAAACAGACCTGAC
ATTTTAGACCCTGCAATATTAAGACCTGGAAGATTTGATAGAATCATAGAAGTCCCAGCTCCTGATGAGAAGGGTAGATT
GGAGATATTGAAGATTCATACAAGAAAGATGAATTTAGCGGAAGATGTCAATTTAGAAGAAATAGCTAAGATGACTGAAG
GATGTGTAGGGGCTGAGTTAAAGGCAATCTGCACAGAGGCAGGGATGAATGCAATTAGGGAGTTAAGGGACTATGTAACA
ATGGATGACTTTAGAAAGGCAGTTGAGAAGATTATGGAGAAAAAGAAAGTTAAAGTTAAGGAACCAGCACACTTGGATGT
TCTCTACAGATAA

Upstream 100 bases:

>100_bases
ATTTTTATTATAATTCCATATGGTATATAAATGATAATCCATAATAAAATAAAATGATTATAATATTCCCTTCACTTAAC
TTAAATTTACCGGTGATATT

Downstream 100 bases:

>100_bases
ACCTTTTTTATTTTTTGACTATTTTAATTTTTATTTTAAATGTAAAACTAAGCAATTAAAAATTTTTGGTGACATTAATG
AACACCTATGGGGATATGTT

Product: proteasome-activating nucleotidase

Products: NA

Alternate protein names: PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKELERENLQLMKENEIL
RRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAME
VDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSEL
VKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPD
ILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVT
MDDFRKAVEKIMEKKKVKVKEPAHLDVLYR

Sequences:

>Translated_430_residues
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKELERENLQLMKENEIL
RRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAME
VDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSEL
VKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPD
ILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVT
MDDFRKAVEKIMEKKKVKVKEPAHLDVLYR
>Mature_430_residues
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKELERENLQLMKENEIL
RRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAME
VDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSEL
VKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPD
ILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVT
MDDFRKAVEKIMEKKKVKVKEPAHLDVLYR

Specific function: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereb

COG id: COG1222

COG function: function code O; ATP-dependent 26S proteasome regulatory subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family

Homologues:

Organism=Homo sapiens, GI24430151, Length=345, Percent_Identity=51.5942028985507, Blast_Score=371, Evalue=1e-103,
Organism=Homo sapiens, GI24497435, Length=321, Percent_Identity=55.4517133956386, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI89064750, Length=368, Percent_Identity=47.8260869565217, Blast_Score=355, Evalue=3e-98,
Organism=Homo sapiens, GI5729991, Length=368, Percent_Identity=47.8260869565217, Blast_Score=355, Evalue=4e-98,
Organism=Homo sapiens, GI21361144, Length=332, Percent_Identity=51.5060240963855, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI24430155, Length=334, Percent_Identity=50.2994011976048, Blast_Score=348, Evalue=6e-96,
Organism=Homo sapiens, GI195539395, Length=357, Percent_Identity=48.1792717086835, Blast_Score=343, Evalue=2e-94,
Organism=Homo sapiens, GI4506209, Length=385, Percent_Identity=43.6363636363636, Blast_Score=325, Evalue=5e-89,
Organism=Homo sapiens, GI6005942, Length=261, Percent_Identity=50.9578544061303, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI300192933, Length=265, Percent_Identity=46.7924528301887, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI157671927, Length=255, Percent_Identity=46.6666666666667, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI7657689, Length=257, Percent_Identity=45.5252918287938, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI21327685, Length=257, Percent_Identity=45.5252918287938, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI24497618, Length=291, Percent_Identity=40.2061855670103, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI229577436, Length=264, Percent_Identity=41.6666666666667, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=45.0413223140496, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI45643123, Length=235, Percent_Identity=46.8085106382979, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI45643125, Length=235, Percent_Identity=46.8085106382979, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI4505725, Length=225, Percent_Identity=43.5555555555556, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4507173, Length=263, Percent_Identity=41.4448669201521, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI7019569, Length=254, Percent_Identity=40.5511811023622, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI194018488, Length=275, Percent_Identity=40, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI5901990, Length=276, Percent_Identity=38.768115942029, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI17865802, Length=240, Percent_Identity=41.6666666666667, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI14149767, Length=276, Percent_Identity=39.1304347826087, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI62177112, Length=276, Percent_Identity=39.1304347826087, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI11875211, Length=268, Percent_Identity=39.5522388059701, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI40806170, Length=268, Percent_Identity=39.5522388059701, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI226371754, Length=241, Percent_Identity=38.5892116182573, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI31377644, Length=269, Percent_Identity=37.546468401487, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI31742536, Length=241, Percent_Identity=35.6846473029046, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI112789543, Length=241, Percent_Identity=35.6846473029046, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI156564401, Length=245, Percent_Identity=39.5918367346939, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI310125282, Length=245, Percent_Identity=39.1836734693878, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310125280, Length=236, Percent_Identity=39.8305084745763, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI40806173, Length=139, Percent_Identity=48.2014388489209, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI64084766, Length=270, Percent_Identity=30, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI116292174, Length=260, Percent_Identity=29.6153846153846, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI75677353, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI40255052, Length=211, Percent_Identity=26.0663507109005, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789568, Length=244, Percent_Identity=49.1803278688525, Blast_Score=237, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17563250, Length=342, Percent_Identity=49.4152046783626, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17554786, Length=367, Percent_Identity=49.591280653951, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25144278, Length=369, Percent_Identity=49.0514905149051, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25144281, Length=369, Percent_Identity=49.0514905149051, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17508701, Length=405, Percent_Identity=44.6913580246914, Blast_Score=351, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI71987364, Length=362, Percent_Identity=45.8563535911602, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI71987372, Length=362, Percent_Identity=45.8563535911602, Blast_Score=343, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI17554784, Length=367, Percent_Identity=47.6839237057221, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17563248, Length=331, Percent_Identity=45.9214501510574, Blast_Score=320, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17505546, Length=273, Percent_Identity=56.7765567765568, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17532375, Length=237, Percent_Identity=50.6329113924051, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17531535, Length=238, Percent_Identity=50, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17508053, Length=262, Percent_Identity=43.5114503816794, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI71994521, Length=275, Percent_Identity=42.9090909090909, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI133931034, Length=251, Percent_Identity=43.4262948207171, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI193206116, Length=251, Percent_Identity=43.4262948207171, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI193206114, Length=251, Percent_Identity=43.4262948207171, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17537217, Length=260, Percent_Identity=42.3076923076923, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17562804, Length=254, Percent_Identity=41.3385826771654, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI115534323, Length=254, Percent_Identity=40.9448818897638, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17554264, Length=232, Percent_Identity=40.948275862069, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25153574, Length=229, Percent_Identity=41.4847161572052, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI193209502, Length=229, Percent_Identity=41.4847161572052, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI86561515, Length=239, Percent_Identity=41.0041841004184, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25146157, Length=384, Percent_Identity=33.0729166666667, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17560432, Length=248, Percent_Identity=38.3064516129032, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17541226, Length=265, Percent_Identity=37.7358490566038, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17541224, Length=265, Percent_Identity=37.7358490566038, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI133901662, Length=283, Percent_Identity=34.982332155477, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI133901658, Length=283, Percent_Identity=34.982332155477, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI32563584, Length=247, Percent_Identity=36.4372469635627, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17508421, Length=240, Percent_Identity=36.6666666666667, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17570397, Length=124, Percent_Identity=34.6774193548387, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566590, Length=124, Percent_Identity=34.6774193548387, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990294, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320197, Length=329, Percent_Identity=52.5835866261398, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321390, Length=369, Percent_Identity=48.5094850948509, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6324833, Length=325, Percent_Identity=51.0769230769231, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6324691, Length=410, Percent_Identity=43.6585365853659, Blast_Score=335, Evalue=9e-93,
Organism=Saccharomyces cerevisiae, GI6320602, Length=381, Percent_Identity=44.6194225721785, Blast_Score=324, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6322704, Length=301, Percent_Identity=50.1661129568106, Blast_Score=320, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6320077, Length=285, Percent_Identity=49.1228070175439, Blast_Score=262, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6320854, Length=291, Percent_Identity=42.2680412371134, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323736, Length=286, Percent_Identity=41.958041958042, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321709, Length=262, Percent_Identity=41.6030534351145, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6323429, Length=275, Percent_Identity=45.8181818181818, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324000, Length=234, Percent_Identity=46.5811965811966, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6325281, Length=249, Percent_Identity=43.3734939759036, Blast_Score=206, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6322994, Length=281, Percent_Identity=38.7900355871886, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6325183, Length=250, Percent_Identity=40, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6325431, Length=249, Percent_Identity=43.3734939759036, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6319554, Length=250, Percent_Identity=40, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322651, Length=246, Percent_Identity=36.5853658536585, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6321465, Length=234, Percent_Identity=40.5982905982906, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320887, Length=253, Percent_Identity=34.7826086956522, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24649446, Length=349, Percent_Identity=51.8624641833811, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19920408, Length=374, Percent_Identity=50.2673796791444, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI18860063, Length=367, Percent_Identity=48.7738419618529, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17738151, Length=329, Percent_Identity=52.2796352583587, Blast_Score=356, Evalue=1e-98,
Organism=Drosophila melanogaster, GI281361487, Length=360, Percent_Identity=47.7777777777778, Blast_Score=354, Evalue=8e-98,
Organism=Drosophila melanogaster, GI24651451, Length=321, Percent_Identity=53.8940809968847, Blast_Score=351, Evalue=6e-97,
Organism=Drosophila melanogaster, GI24640100, Length=328, Percent_Identity=51.219512195122, Blast_Score=341, Evalue=5e-94,
Organism=Drosophila melanogaster, GI24663015, Length=390, Percent_Identity=44.1025641025641, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI17137738, Length=319, Percent_Identity=47.3354231974922, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI161076486, Length=237, Percent_Identity=51.0548523206751, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI17137560, Length=237, Percent_Identity=51.0548523206751, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI161076488, Length=237, Percent_Identity=51.0548523206751, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24665814, Length=255, Percent_Identity=47.0588235294118, Blast_Score=231, Evalue=7e-61,
Organism=Drosophila melanogaster, GI28574878, Length=255, Percent_Identity=47.0588235294118, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI19921202, Length=253, Percent_Identity=42.2924901185771, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24660075, Length=233, Percent_Identity=46.7811158798283, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281365776, Length=233, Percent_Identity=46.7811158798283, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI45552965, Length=233, Percent_Identity=46.7811158798283, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24658770, Length=265, Percent_Identity=44.1509433962264, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24652279, Length=194, Percent_Identity=51.0309278350515, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24656825, Length=270, Percent_Identity=39.6296296296296, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24639391, Length=270, Percent_Identity=41.4814814814815, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24656820, Length=270, Percent_Identity=39.6296296296296, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI281363136, Length=247, Percent_Identity=42.1052631578947, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI78707192, Length=247, Percent_Identity=42.1052631578947, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI18859657, Length=253, Percent_Identity=41.501976284585, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21355121, Length=271, Percent_Identity=35.4243542435424, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24581396, Length=262, Percent_Identity=38.5496183206107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI281360144, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281360140, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281360146, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281360138, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281360136, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24644411, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281360142, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21357333, Length=253, Percent_Identity=37.1541501976285, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI20129423, Length=270, Percent_Identity=37.4074074074074, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI20129529, Length=238, Percent_Identity=38.2352941176471, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17864540, Length=239, Percent_Identity=39.3305439330544, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI28573010, Length=239, Percent_Identity=39.7489539748954, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571849, Length=262, Percent_Identity=37.4045801526718, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571847, Length=262, Percent_Identity=37.4045801526718, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24644145, Length=236, Percent_Identity=38.135593220339, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI45554047, Length=179, Percent_Identity=45.8100558659218, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24639486, Length=259, Percent_Identity=30.8880308880309, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAN_METJA (Q58576)

Other databases:

- EMBL:   L77117
- PIR:   G64446
- RefSeq:   NP_248170.1
- PDB:   3H43
- PDB:   3H4M
- PDB:   3IPM
- PDBsum:   3H43
- PDBsum:   3H4M
- PDBsum:   3IPM
- ProteinModelPortal:   Q58576
- SMR:   Q58576
- GeneID:   1452074
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1176
- NMPDR:   fig|243232.1.peg.1207
- TIGR:   MJ1176
- HOGENOM:   HBG724153
- OMA:   KPTHAAM
- ProtClustDB:   PRK03992
- BioCyc:   MJAN243232:MJ_1176-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00553
- InterPro:   IPR005937
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- SMART:   SM00382
- TIGRFAMs:   TIGR01242

Pfam domain/function: PF00004 AAA

EC number: 3.4.24.- [C]

Molecular weight: Translated: 48690; Mature: 48690

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00674 AAA

Important sites: BINDING 353-353

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKKELERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEH
SHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVRYEDIGGLEKQMQ
HHCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHCCCHHHHHH
EIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSEL
HHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
VKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAE
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLA
HCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEHHHCCCH
EDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAVEKIMEKKKVKVK
HCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
EPAHLDVLYR
CCCCEEEECC
>Mature Secondary Structure
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKKELERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEH
SHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVRYEDIGGLEKQMQ
HHCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHCCCHHHHHH
EIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSEL
HHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
VKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAE
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLA
HCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEHHHCCCH
EDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAVEKIMEKKKVKVK
HCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
EPAHLDVLYR
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 10692374; 10473546