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The map label for this gene is fwdE

Identifier: 15669354

GI number: 15669354

Start: 1106284

End: 1106724

Strand: Direct

Name: fwdE

Synonym: MJ1165

Alternate gene names: 15669354

Gene position: 1106284-1106724 (Clockwise)

Preceding gene: 15669352

Following gene: 15669355

Centisome position: 66.44

GC content: 34.69

Gene sequence:

>441_bases
ATGCCAGAGCATATTCTCTCCGGAATAAAGGCAATAGTGGCAATGAAATTAAGAAGAAAAGGGCTTTTGCAGAAGGAAAT
AGCAAAAATTATTAAGAGCGATAGGTCAATCGTTTCTCATTATCTCTCTGGGAGGTATCCAAAGGAAAAAATCTTAAATG
TTGCAAAAATTATTGAAGAAATGCCACCACAATATGGAGCAAAGTTTATTCATTCTTTAACTGATAATAAAGAGCTTGCA
AAGAACTTAATTAAAGAATTATATGGTATAAAACTTTTCTGGGATGAAAATTCCTGCATAGCTTGCGGTTCCTGTTTAGG
GTGTGCAGCACTCACACTTGATAACTTCACTGTTGGTATAGACGAAGATACCTGCCATCTATGTGCATCTTGCATATTTA
GATGTCCAACAAACTCATTAAAATTCATTAAGGAGGAATAA

Upstream 100 bases:

>100_bases
TGAGCAAGACACACACCTATATAAAAAAGTTTCTACTTAAACTTCATACATAGTATTTATAAATGAAAATCATCAACTAA
CATAATGTCCATGTGAGACG

Downstream 100 bases:

>100_bases
CCATGATTGAGCAAATAAAAGAGGTCTATGAAAATGGATTTACCATATATAGAGATGGTGAAGTAGAAAAAAGAGAACTC
TGTTGGAACGATGAACTATG

Product: formylmethanofuran dehydrogenase subunit FwdE

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MPEHILSGIKAIVAMKLRRKGLLQKEIAKIIKSDRSIVSHYLSGRYPKEKILNVAKIIEEMPPQYGAKFIHSLTDNKELA
KNLIKELYGIKLFWDENSCIACGSCLGCAALTLDNFTVGIDEDTCHLCASCIFRCPTNSLKFIKEE

Sequences:

>Translated_146_residues
MPEHILSGIKAIVAMKLRRKGLLQKEIAKIIKSDRSIVSHYLSGRYPKEKILNVAKIIEEMPPQYGAKFIHSLTDNKELA
KNLIKELYGIKLFWDENSCIACGSCLGCAALTLDNFTVGIDEDTCHLCASCIFRCPTNSLKFIKEE
>Mature_145_residues
PEHILSGIKAIVAMKLRRKGLLQKEIAKIIKSDRSIVSHYLSGRYPKEKILNVAKIIEEMPPQYGAKFIHSLTDNKELAK
NLIKELYGIKLFWDENSCIACGSCLGCAALTLDNFTVGIDEDTCHLCASCIFRCPTNSLKFIKEE

Specific function: Unknown

COG id: COG1146

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDE_METJA (Q58565)

Other databases:

- EMBL:   L77117
- PIR:   D64445
- RefSeq:   NP_248159.1
- ProteinModelPortal:   Q58565
- GeneID:   1452063
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1165
- NMPDR:   fig|243232.1.peg.1196
- TIGR:   MJ1165
- HOGENOM:   HBG551378
- OMA:   MPEHILS
- ProtClustDB:   CLSK876478
- BioCyc:   MJAN243232:MJ_1165-MONOMER
- InterPro:   IPR017896
- InterPro:   IPR017900

Pfam domain/function: NA

EC number: 1.2.99.5

Molecular weight: Translated: 16404; Mature: 16272

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEHILSGIKAIVAMKLRRKGLLQKEIAKIIKSDRSIVSHYLSGRYPKEKILNVAKIIEE
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MPPQYGAKFIHSLTDNKELAKNLIKELYGIKLFWDENSCIACGSCLGCAALTLDNFTVGI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHCCEEECC
DEDTCHLCASCIFRCPTNSLKFIKEE
CCHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
PEHILSGIKAIVAMKLRRKGLLQKEIAKIIKSDRSIVSHYLSGRYPKEKILNVAKIIEE
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MPPQYGAKFIHSLTDNKELAKNLIKELYGIKLFWDENSCIACGSCLGCAALTLDNFTVGI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHCCEEECC
DEDTCHLCASCIFRCPTNSLKFIKEE
CCHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087