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The map label for this gene is fwdF

Identifier: 15669355

GI number: 15669355

Start: 1106727

End: 1107794

Strand: Direct

Name: fwdF

Synonym: MJ1166

Alternate gene names: 15669355

Gene position: 1106727-1107794 (Clockwise)

Preceding gene: 15669354

Following gene: 15669356

Centisome position: 66.47

GC content: 36.14

Gene sequence:

>1068_bases
ATGATTGAGCAAATAAAAGAGGTCTATGAAAATGGATTTACCATATATAGAGATGGTGAAGTAGAAAAAAGAGAACTCTG
TTGGAACGATGAACTATGTGTTGGATGTGGTATCTGTGCAGATATCTGCCCAGTTAATGCCATTGCTATGGGTCCTTTAG
GAGCTATTGCTAAAGGAGACATAATAGCTCCAAAATTGGATATTGATAAAGATGTCTGTGTTTTATGTGGAATGTGTGCT
TCAGCATGTCCATTTGATGCATTGGATTTGAAAATCAATGGTAAATCAATAAAAGAAGATGAGAGATATCCAAAAATTAA
GAGAGATATTAAAGTTTATCAAGACAAGTGTGTTTTATGTGAGCAGTGTGAAATGGTTTGTCCTCAAGGGGCTATAGTTG
TTGAAAGAGAATTGGCAGAGAGGGAGAAGTTTGTTATCGGAGAGATAAACATAAACAAAGAGAAATGTGTTCTATGTGGA
ATCTGTGCTGAATACTGTCCAGCTGATGCTATTAATTTAAAATACAACTACCCAACTCCATCAAACCCAAAACCAATAAC
TGATATTGAAGTTGATAAGGATAAGTGTGTCTTCTGTAAGGTTTGTGAATTCGTCTGTCCGCATGATGCTATTGAGGTTA
TCTGTTACAAGTGTCCAATGATGAAGAGAATTCCACAAGCTAAGTTGTATGAGGATATTACAGGAAAAACAGTTATTGAT
AAAGATGCATGTGTAACCTGTGGATGGTGTGCCTTTATCTGTCCAGCTGAAGCTATTGAAGTTGAGAAGCCATTCAAAGG
AGAGTTAATAATCGATGTAAATGCATGTAACGCTTGTGGAGCCTGTATTTCCATATGTCCATGTAGTGCATTAGAATTCC
CAAAACCAAAAGACAAGGCAGAAAAAGTTCCAAGAATCATTGTAAATCAAAACCTCTGTGTGTTGTGTGGAGCTTGTGCT
AAAGCATGTCCAGTTAATGCTATAAAAGTTAAGAGAACAGAAATTAACTTTGAAAGAGAACCAAAGGCAATTGCATGGAA
AGAAGCGTTTAAAAAGTTAATGGGTTAA

Upstream 100 bases:

>100_bases
ACTTCACTGTTGGTATAGACGAAGATACCTGCCATCTATGTGCATCTTGCATATTTAGATGTCCAACAAACTCATTAAAA
TTCATTAAGGAGGAATAACC

Downstream 100 bases:

>100_bases
ATTGAAAATACCTTAAAGAATATTAAAAATCATTAAAAGGTGAGGAAATGAAAGCTTATGAGTTGGTAGTTTATCCAGAA
AGATGCCACGGATGTGGAAA

Product: formylmethanofuran dehydrogenase subunit FwdF

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGDIIAPKLDIDKDVCVLCGMCA
SACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLCEQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCG
ICAEYCPADAINLKYNYPTPSNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVID
KDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKAEKVPRIIVNQNLCVLCGACA
KACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG

Sequences:

>Translated_355_residues
MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGDIIAPKLDIDKDVCVLCGMCA
SACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLCEQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCG
ICAEYCPADAINLKYNYPTPSNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVID
KDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKAEKVPRIIVNQNLCVLCGACA
KACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG
>Mature_355_residues
MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGDIIAPKLDIDKDVCVLCGMCA
SACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLCEQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCG
ICAEYCPADAINLKYNYPTPSNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVID
KDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKAEKVPRIIVNQNLCVLCGACA
KACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG

Specific function: Involved In Electron Transfer. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDF_METJA (Q58566)

Other databases:

- EMBL:   L77117
- PIR:   E64445
- RefSeq:   NP_248160.1
- ProteinModelPortal:   Q58566
- GeneID:   1452064
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1166
- NMPDR:   fig|243232.1.peg.1197
- TIGR:   MJ1166
- HOGENOM:   HBG542048
- OMA:   CVLCEQC
- ProtClustDB:   CLSK876479
- BioCyc:   MJAN243232:MJ_1166-MONOMER
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR016459
- PIRSF:   PIRSF005658

Pfam domain/function: PF00037 Fer4

EC number: 1.2.99.5

Molecular weight: Translated: 39344; Mature: 39344

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

10.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
12.1 %Cys+Met (Translated Protein)
10.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
12.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGD
CHHHHHHHHHCCCEEEECCCCCHHHHCCCCCEEEECCCHHHHCCCCEEECCCCCCCCCCC
IIAPKLDIDKDVCVLCGMCASACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLC
EECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCGICAEYCPADAINLKYNYPTP
HHHHHHCCCCCEEEEHHHHHCCCEEEEEEECCCCCEEEEEHHHHHCCCCEEEEEECCCCC
SNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVID
CCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHCCHHHHHHHCCCCEEEC
KDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKA
CCCCEECCHHHHHCCHHHEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHH
EKVPRIIVNQNLCVLCGACAKACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG
HHCCEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIEQIKEVYENGFTIYRDGEVEKRELCWNDELCVGCGICADICPVNAIAMGPLGAIAKGD
CHHHHHHHHHCCCEEEECCCCCHHHHCCCCCEEEECCCHHHHCCCCEEECCCCCCCCCCC
IIAPKLDIDKDVCVLCGMCASACPFDALDLKINGKSIKEDERYPKIKRDIKVYQDKCVLC
EECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQCEMVCPQGAIVVERELAEREKFVIGEININKEKCVLCGICAEYCPADAINLKYNYPTP
HHHHHHCCCCCEEEEHHHHHCCCEEEEEEECCCCCEEEEEHHHHHCCCCEEEEEECCCCC
SNPKPITDIEVDKDKCVFCKVCEFVCPHDAIEVICYKCPMMKRIPQAKLYEDITGKTVID
CCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHCCHHHHHHHCCCCEEEC
KDACVTCGWCAFICPAEAIEVEKPFKGELIIDVNACNACGACISICPCSALEFPKPKDKA
CCCCEECCHHHHHCCHHHEECCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHH
EKVPRIIVNQNLCVLCGACAKACPVNAIKVKRTEINFEREPKAIAWKEAFKKLMG
HHCCEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087