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The map label for this gene is comB [H]

Identifier: 15669327

GI number: 15669327

Start: 1080043

End: 1080816

Strand: Reverse

Name: comB [H]

Synonym: MJ1140

Alternate gene names: 15669327

Gene position: 1080816-1080043 (Counterclockwise)

Preceding gene: 15669331

Following gene: 15669326

Centisome position: 64.92

GC content: 30.1

Gene sequence:

>774_bases
TTGTTATCATTCCAACAAGTTGTAAAAATCCATCTAATCCTAAGATGCTTATCACCTCAGATATTCCAAAAATTTATAAA
AATTAAAATGGTTGATAGCATGATAACTCTATGTAACAGATTTACTGAATATAAATGTGGAAATGTAGCTATAGTGGTTG
ATGTTTTAAGGGCATCTACTACAATAACAACACTCCTATCATTTATAGATGAAGTATATATAACTACATCAACATCTAAA
AAAGAAAATGCCATATACATTGGAGAGAGAAAAGGAAGAAAGATAGAAGGATTTGATTTTGGAAACTCCCCAACTGAGAT
TTTAGCAAATAAAGATATTATAAAAGAAAGATATGAAAATGGAGAAAAGGTGATTTTAACAACCACAAATGGAACGAGGG
TTTTAAAAAGCTTAGATGCTGAGCATATTTTTATAGGGGCAATTGTTAATGCAAAGTATGTTGCTAAGGCGGTTGAAGAT
TTTGAAGATGTGAGCTTAGTCCCCTGCCATAGAGAAAATAACTTTGCAATAGATGACTTTATTGGATGTGGAGTTATAGC
TAAATATCTAAATGGAGAGTTTGATGAATTTATCAAGGCTGCTTTAGAATTAACTAAACATGATTGGATGTCTTTGATTT
TAAATTCGTCATCTGCAGAGAATTTAAAGAATCTTGGTTATGAGAAAGATGTTACGTTTGCAATATTGGAAAATAGTATA
GATGCAGTTGGAATATATAAAAAAGATAAGAGCAAAGTTGTTAGATTTAAATAA

Upstream 100 bases:

>100_bases
AAAGCCAAGCTTGGGAATATCAATTTATTCTTTTTTAGTAATATATAGCTAATGATTAAAATTAGGATGAATGATATAAA
TGCCAGTGCAAATATAGCTA

Downstream 100 bases:

>100_bases
AATTTTGTGATAACATGAGAATCGATATAAACAGAATAGAAAAGGAAGAGGATATAAAATTACTTAAAGAACTGAAATGG
AATGGATTTGTTTTTTATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLSFQQVVKIHLILRCLSPQIFQKFIKIKMVDSMITLCNRFTEYKCGNVAIVVDVLRASTTITTLLSFIDEVYITTSTSK
KENAIYIGERKGRKIEGFDFGNSPTEILANKDIIKERYENGEKVILTTTNGTRVLKSLDAEHIFIGAIVNAKYVAKAVED
FEDVSLVPCHRENNFAIDDFIGCGVIAKYLNGEFDEFIKAALELTKHDWMSLILNSSSAENLKNLGYEKDVTFAILENSI
DAVGIYKKDKSKVVRFK

Sequences:

>Translated_257_residues
MLSFQQVVKIHLILRCLSPQIFQKFIKIKMVDSMITLCNRFTEYKCGNVAIVVDVLRASTTITTLLSFIDEVYITTSTSK
KENAIYIGERKGRKIEGFDFGNSPTEILANKDIIKERYENGEKVILTTTNGTRVLKSLDAEHIFIGAIVNAKYVAKAVED
FEDVSLVPCHRENNFAIDDFIGCGVIAKYLNGEFDEFIKAALELTKHDWMSLILNSSSAENLKNLGYEKDVTFAILENSI
DAVGIYKKDKSKVVRFK
>Mature_257_residues
MLSFQQVVKIHLILRCLSPQIFQKFIKIKMVDSMITLCNRFTEYKCGNVAIVVDVLRASTTITTLLSFIDEVYITTSTSK
KENAIYIGERKGRKIEGFDFGNSPTEILANKDIIKERYENGEKVILTTTNGTRVLKSLDAEHIFIGAIVNAKYVAKAVED
FEDVSLVPCHRENNFAIDDFIGCGVIAKYLNGEFDEFIKAALELTKHDWMSLILNSSSAENLKNLGYEKDVTFAILENSI
DAVGIYKKDKSKVVRFK

Specific function: Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)-phospholactate and (S)-phosphoglycerate [H]

COG id: COG2045

COG function: function code HR; Phosphosulfolactate phosphohydrolase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005238
- InterPro:   IPR022995 [H]

Pfam domain/function: PF04029 2-ph_phosp [H]

EC number: =3.1.3.71 [H]

Molecular weight: Translated: 29029; Mature: 29029

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFQQVVKIHLILRCLSPQIFQKFIKIKMVDSMITLCNRFTEYKCGNVAIVVDVLRAST
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHH
TITTLLSFIDEVYITTSTSKKENAIYIGERKGRKIEGFDFGNSPTEILANKDIIKERYEN
HHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC
GEKVILTTTNGTRVLKSLDAEHIFIGAIVNAKYVAKAVEDFEDVSLVPCHRENNFAIDDF
CCEEEEEECCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHH
IGCGVIAKYLNGEFDEFIKAALELTKHDWMSLILNSSSAENLKNLGYEKDVTFAILENSI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
DAVGIYKKDKSKVVRFK
CEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLSFQQVVKIHLILRCLSPQIFQKFIKIKMVDSMITLCNRFTEYKCGNVAIVVDVLRAST
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHH
TITTLLSFIDEVYITTSTSKKENAIYIGERKGRKIEGFDFGNSPTEILANKDIIKERYEN
HHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCC
GEKVILTTTNGTRVLKSLDAEHIFIGAIVNAKYVAKAVEDFEDVSLVPCHRENNFAIDDF
CCEEEEEECCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHH
IGCGVIAKYLNGEFDEFIKAALELTKHDWMSLILNSSSAENLKNLGYEKDVTFAILENSI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
DAVGIYKKDKSKVVRFK
CEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11589710 [H]