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The map label for this gene is cca

Identifier: 15669299

GI number: 15669299

Start: 1052535

End: 1053884

Strand: Reverse

Name: cca

Synonym: MJ1111

Alternate gene names: 15669299

Gene position: 1053884-1052535 (Counterclockwise)

Preceding gene: 15669300

Following gene: 15669298

Centisome position: 63.3

GC content: 30.74

Gene sequence:

>1350_bases
GTGATTGTTTTGACAATAGAGGAGATATTAAAAGAAGTTTTAAATGAAATAAAGCCTTCAAAGGAAGATATGGAAAAACT
GCAACTTAAAGCTAATGAAATCATTGATAAAATTTGGGAAATAGTCAGAGAGAATAGCTATCCAATCTTAGAGGTTTTAT
TGGTTGGCTCTTCAGCAAGAAACACAAATTTAAAGGATGACTATGATATTGATATTTTTGTATTGTTTGACAAATCAGTT
TCTGAAGATGAATTAGAAGAGATTGGATTAAAAATAGGAACAGAGGCAATAAAGAGGTTAAACGGCTCTTATAACATAAA
CTATGCCTCTCATCCCTATGTTAATGGTGAAGTTGATGGTTATGAAGTTGATATAGTCCCATGCTATAAGATAGACTTTG
GAGAAAAAATAATATCTGCAGTTGATAGAACTCCATTGCATCATAAATTTTTAATTAGTAGGTTGAATGAAAGGCTTTGT
GATGAAGTTAGGTTGTTAAAGGCATTTTTAAAGAGTTTGGGATTATATGGTTCTGACGTAAAAACTAAAGGATTCTCTGG
CTATTTATGTGAGTTGTTGATTCTACACTATGGTTCATTCATAAATCTATTAAAAGAGGCTCAAAATTGGAGAATTGGGA
AGAAGATAATTTTAAAAGACATATTTGAAATTTATAAAGATGTTGATATTAATAAGCTAAAAAAGTTTGATGAACCGTTT
ATTGTCTATGACCCAGTAGATTTAAATAGAAATGTAGCCTCTCCGTTAAGCAAAGATAACTTCTGCAGATTCATATTCTA
CTCAAGACAATTTTTAAAAAATCCTTCTATTGAGTTCTTTAAGGACTATGCTAAAAAGTTAGAGGAGATTTTGGAAAATA
GAGAGCATGGATATAGATTAATATTAAAAATCCCAAGGGAGAATGTTGTTGATGACATCATCTATCCACAGATGGAGAAG
CTTCAAAAAAGTATAAATAAAGTTATTGTTAAAAATGAATTTGTAATTTTGAATAGCAAGTGTTTTGCAGATGATAACTA
TTGCTATCTGTATTGGGAATTTTTAGTGTATGAACTACCAAAAATTGCTTTGAGAGAAGGGCCTCCGGTATTTGAGAAGG
AGAGGGCAGAGAGGTTTTTAAAGAAGTATGGTAAAGTTTTTATTAGGGATTGTAAGTTATTTGCCTATACAGAGAGAGAA
TATTCTCACATAATCGATTTATTTAAAGACATTGTTAATGGGAATTTACAGAATATCTCTATTCCGAAGTATGTAAATCC
AAGAAACGGAAAGATTATTGAGTTGAATAGCCATGGAGAGCACAAGCAATTTAATAAAGAATGCCAATGA

Upstream 100 bases:

>100_bases
CCATAGGAGGAAACCTCCTATTGGGATACCTCCCGTCCATTAAGTTAGGGCTTTCAGCCCTAATTAATGTCCATTATTAA
TAACAATAAGTTTTAGTTCG

Downstream 100 bases:

>100_bases
ATTTTTGGATTCTTTAAATGAGATTAACGATAAATTAAAAGAGGTAGTTGGTAAAATAAAAAACAAAACAATTGATAAAA
CTAAATTATCTGATATTATA

Product: tRNA CCA-pyrophosphorylase

Products: NA

Alternate protein names: tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl- transferase; tRNA nucleotidyltransferase; tRNA-NT

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MIVLTIEEILKEVLNEIKPSKEDMEKLQLKANEIIDKIWEIVRENSYPILEVLLVGSSARNTNLKDDYDIDIFVLFDKSV
SEDELEEIGLKIGTEAIKRLNGSYNINYASHPYVNGEVDGYEVDIVPCYKIDFGEKIISAVDRTPLHHKFLISRLNERLC
DEVRLLKAFLKSLGLYGSDVKTKGFSGYLCELLILHYGSFINLLKEAQNWRIGKKIILKDIFEIYKDVDINKLKKFDEPF
IVYDPVDLNRNVASPLSKDNFCRFIFYSRQFLKNPSIEFFKDYAKKLEEILENREHGYRLILKIPRENVVDDIIYPQMEK
LQKSINKVIVKNEFVILNSKCFADDNYCYLYWEFLVYELPKIALREGPPVFEKERAERFLKKYGKVFIRDCKLFAYTERE
YSHIIDLFKDIVNGNLQNISIPKYVNPRNGKIIELNSHGEHKQFNKECQ

Sequences:

>Translated_449_residues
MIVLTIEEILKEVLNEIKPSKEDMEKLQLKANEIIDKIWEIVRENSYPILEVLLVGSSARNTNLKDDYDIDIFVLFDKSV
SEDELEEIGLKIGTEAIKRLNGSYNINYASHPYVNGEVDGYEVDIVPCYKIDFGEKIISAVDRTPLHHKFLISRLNERLC
DEVRLLKAFLKSLGLYGSDVKTKGFSGYLCELLILHYGSFINLLKEAQNWRIGKKIILKDIFEIYKDVDINKLKKFDEPF
IVYDPVDLNRNVASPLSKDNFCRFIFYSRQFLKNPSIEFFKDYAKKLEEILENREHGYRLILKIPRENVVDDIIYPQMEK
LQKSINKVIVKNEFVILNSKCFADDNYCYLYWEFLVYELPKIALREGPPVFEKERAERFLKKYGKVFIRDCKLFAYTERE
YSHIIDLFKDIVNGNLQNISIPKYVNPRNGKIIELNSHGEHKQFNKECQ
>Mature_449_residues
MIVLTIEEILKEVLNEIKPSKEDMEKLQLKANEIIDKIWEIVRENSYPILEVLLVGSSARNTNLKDDYDIDIFVLFDKSV
SEDELEEIGLKIGTEAIKRLNGSYNINYASHPYVNGEVDGYEVDIVPCYKIDFGEKIISAVDRTPLHHKFLISRLNERLC
DEVRLLKAFLKSLGLYGSDVKTKGFSGYLCELLILHYGSFINLLKEAQNWRIGKKIILKDIFEIYKDVDINKLKKFDEPF
IVYDPVDLNRNVASPLSKDNFCRFIFYSRQFLKNPSIEFFKDYAKKLEEILENREHGYRLILKIPRENVVDDIIYPQMEK
LQKSINKVIVKNEFVILNSKCFADDNYCYLYWEFLVYELPKIALREGPPVFEKERAERFLKKYGKVFIRDCKLFAYTERE
YSHIIDLFKDIVNGNLQNISIPKYVNPRNGKIIELNSHGEHKQFNKECQ

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG1746

COG function: function code J; tRNA nucleotidyltransferase (CCA-adding enzyme)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCA_METJA (Q58511)

Other databases:

- EMBL:   L77117
- RefSeq:   NP_248104.1
- ProteinModelPortal:   Q58511
- SMR:   Q58511
- GeneID:   1452008
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1111
- NMPDR:   fig|243232.1.peg.1141
- TIGR:   MJ1111
- HOGENOM:   HBG645243
- OMA:   CEKIISA
- ProtClustDB:   PRK13300
- BioCyc:   MJAN243232:MJ_1111-MONOMER
- HAMAP:   MF_01264
- InterPro:   IPR008229
- InterPro:   IPR002934
- InterPro:   IPR011068
- InterPro:   IPR015329
- PIRSF:   PIRSF005335
- TIGRFAMs:   TIGR03671

Pfam domain/function: PF01909 NTP_transf_2; PF09249 tRNA_NucTransf2; SSF55003 PAP_C

EC number: =2.7.7.21; =2.7.7.25

Molecular weight: Translated: 52785; Mature: 52785

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: BINDING 57-57 BINDING 60-60 BINDING 147-147 BINDING 167-167 BINDING 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLTIEEILKEVLNEIKPSKEDMEKLQLKANEIIDKIWEIVRENSYPILEVLLVGSSAR
CEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCCC
NTNLKDDYDIDIFVLFDKSVSEDELEEIGLKIGTEAIKRLNGSYNINYASHPYVNGEVDG
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
YEVDIVPCYKIDFGEKIISAVDRTPLHHKFLISRLNERLCDEVRLLKAFLKSLGLYGSDV
EEEEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KTKGFSGYLCELLILHYGSFINLLKEAQNWRIGKKIILKDIFEIYKDVDINKLKKFDEPF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
IVYDPVDLNRNVASPLSKDNFCRFIFYSRQFLKNPSIEFFKDYAKKLEEILENREHGYRL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
ILKIPRENVVDDIIYPQMEKLQKSINKVIVKNEFVILNSKCFADDNYCYLYWEFLVYELP
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEECCCCEEEEHHHHHHHHCC
KIALREGPPVFEKERAERFLKKYGKVFIRDCKLFAYTEREYSHIIDLFKDIVNGNLQNIS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCCCC
IPKYVNPRNGKIIELNSHGEHKQFNKECQ
CCCCCCCCCCEEEEECCCCCHHHHCCCCC
>Mature Secondary Structure
MIVLTIEEILKEVLNEIKPSKEDMEKLQLKANEIIDKIWEIVRENSYPILEVLLVGSSAR
CEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCCC
NTNLKDDYDIDIFVLFDKSVSEDELEEIGLKIGTEAIKRLNGSYNINYASHPYVNGEVDG
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
YEVDIVPCYKIDFGEKIISAVDRTPLHHKFLISRLNERLCDEVRLLKAFLKSLGLYGSDV
EEEEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KTKGFSGYLCELLILHYGSFINLLKEAQNWRIGKKIILKDIFEIYKDVDINKLKKFDEPF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
IVYDPVDLNRNVASPLSKDNFCRFIFYSRQFLKNPSIEFFKDYAKKLEEILENREHGYRL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
ILKIPRENVVDDIIYPQMEKLQKSINKVIVKNEFVILNSKCFADDNYCYLYWEFLVYELP
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEECCCCEEEEHHHHHHHHCC
KIALREGPPVFEKERAERFLKKYGKVFIRDCKLFAYTEREYSHIIDLFKDIVNGNLQNIS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHCCCCCCCC
IPKYVNPRNGKIIELNSHGEHKQFNKECQ
CCCCCCCCCCEEEEECCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087