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The map label for this gene is mraY [C]

Identifier: 15669300

GI number: 15669300

Start: 1054003

End: 1054908

Strand: Reverse

Name: mraY [C]

Synonym: MJ1113

Alternate gene names: 15669300

Gene position: 1054908-1054003 (Counterclockwise)

Preceding gene: 15669301

Following gene: 15669299

Centisome position: 63.36

GC content: 29.91

Gene sequence:

>906_bases
ATGGGGCATTATTTTATCAACTTATTTACATATACAATAATTGCTTTTATATTTTCAGCAGTATTGTGTAAATTTTTAAT
GAAGAAGATGATTAATTATAAATTTGGCTATGATTTGCATAAAAAAGAGAAGATTAAAGTTCCAGAGATGGGGGGCTTAG
CAGTATTGTTTTCTAATGCTTTATTTATCCCATTTGTAAATCCAATTTTTGTTTTACCAATAATTACTGCTGGAATTATA
GGAATTGTTGATGATATAGCTAAGCTCTCACCAAAAGAAAAATTAATATTGTTATTTATTTCTGGTTTGATAATAGGAAT
TTTGTTTTATAACAATTCTTATGTTAATTTGATAGAAATTTTGATTATTGCTTTAGGAATCATGATTTCCTCAAATTTAA
CTAATATGTTAGCTGGTTTTAATGGATTGGAGATAGGAATGGGAGTTATAGCTTCTATTTCATTAGCTTTGGTTTTATTC
TTAGATAATTATACAACTGGATTTTTATCCGCTTTGATATTCTCTGCATCCTATTTAGGGCTATTGATATTTAACAAATA
TCCAGCAAAGGTTTTTCCAGGAGATGTTGGAACTCTACCAATTGGAGCTTTCTTAGCTGTCTTAGCAGTAGTTTATAAGG
AATATATCCCATTTTTAGTTATAATGATGCCTTATGTGATAGATGCCTCTTTAAAATATCTAAGTGCTGGGGTTATGAGT
AGGGATGAGCATAAACCAACAACTCTCAAAGAAGATGGGAAGCTATACTATATAGGTGGCTATCTATCCCTACCAAGGCT
TATATTGAAGTATAAACCAATGAGAGAGCCTCACTTAGTTACAGTTTTATGGATAATTGGGATATTCTTTGGTATAGTTG
GGATTTTAATATCATTAATAGCATGA

Upstream 100 bases:

>100_bases
AAGTAAGGAAAATAATAAAAGAATTTCTATAATTTTTTAGCAAAAAACATATATATCCTAAACTTTAACTTCTTTTATCT
TCATTATAAAGGGGATAGTT

Downstream 100 bases:

>100_bases
TGGTGATTGTTTTGAAAACCATAGGAGGAAACCTCCTATTGGGATACCTCCCGTCCATTAAGTTAGGGCTTTCAGCCCTA
ATTAATGTCCATTATTAATA

Product: N-acetylglucosamine-1-phosphate transferase

Products: UMP; N-acetyl-D-glucosaminyl-diphosphodolichol

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGHYFINLFTYTIIAFIFSAVLCKFLMKKMINYKFGYDLHKKEKIKVPEMGGLAVLFSNALFIPFVNPIFVLPIITAGII
GIVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIEILIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLF
LDNYTTGFLSALIFSASYLGLLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVMS
RDEHKPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILISLIA

Sequences:

>Translated_301_residues
MGHYFINLFTYTIIAFIFSAVLCKFLMKKMINYKFGYDLHKKEKIKVPEMGGLAVLFSNALFIPFVNPIFVLPIITAGII
GIVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIEILIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLF
LDNYTTGFLSALIFSASYLGLLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVMS
RDEHKPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILISLIA
>Mature_300_residues
GHYFINLFTYTIIAFIFSAVLCKFLMKKMINYKFGYDLHKKEKIKVPEMGGLAVLFSNALFIPFVNPIFVLPIITAGIIG
IVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIEILIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLFL
DNYTTGFLSALIFSASYLGLLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVMSR
DEHKPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILISLIA

Specific function: First Step Of The Lipid Cycle Reactions In The Biosynthesis Of The Cell Wall Peptidoglycan. [C]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1113_METJA (Q58513)

Other databases:

- EMBL:   L77117
- PIR:   H64438
- RefSeq:   NP_248105.1
- ProteinModelPortal:   Q58513
- GeneID:   1452009
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1113
- NMPDR:   fig|243232.1.peg.1142
- TIGR:   MJ1113
- HOGENOM:   HBG553517
- OMA:   NMLAGFN
- ProtClustDB:   CLSK876456
- BioCyc:   MJAN243232:MJ_1113-MONOMER
- InterPro:   IPR000715
- PANTHER:   PTHR22926

Pfam domain/function: PF00953 Glycos_transf_4

EC number: 2.7.8.15

Molecular weight: Translated: 33364; Mature: 33233

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdceb648)-; HASH(0xdd6de7c)-; HASH(0xddeeb18)-; HASH(0xe1af63c)-; HASH(0xe1ad2e4)-; HASH(0xd26c7f4)-; HASH(0xe1ab3b4)-; HASH(0xe1af678)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHYFINLFTYTIIAFIFSAVLCKFLMKKMINYKFGYDLHKKEKIKVPEMGGLAVLFSNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCHHHHHHCC
LFIPFVNPIFVLPIITAGIIGIVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLFLDNYTTGFLSALIFSASYLG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVMS
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDEHKPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILISLI
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
A
H
>Mature Secondary Structure 
GHYFINLFTYTIIAFIFSAVLCKFLMKKMINYKFGYDLHKKEKIKVPEMGGLAVLFSNA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCHHHHHHCC
LFIPFVNPIFVLPIITAGIIGIVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLFLDNYTTGFLSALIFSASYLG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVMS
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDEHKPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILISLI
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
A
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-glucosamine; dolichyl phosphate

Specific reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087