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The map label for this gene is coaD

Identifier: 15669219

GI number: 15669219

Start: 962491

End: 962934

Strand: Direct

Name: coaD

Synonym: MJ1030

Alternate gene names: 15669219

Gene position: 962491-962934 (Clockwise)

Preceding gene: 15669218

Following gene: 15669220

Centisome position: 57.81

GC content: 28.38

Gene sequence:

>444_bases
ATGAAGGTAGTAGTAGGAGGAACATTTGATATTCTGCATAGAGGGCATAAGGAGCTTTTAAAATTTGCATCCTCTTTAGG
AAAATTAACTATAGGAATAACAAGTGATGAATTTGCCAAAAAATATAAAACACATAAAATAAATGATTTAAAAACAAGAA
TAGAAAATTTAAAAAAGTTTTTGGATAGTATTAAAGCTGATTATGAAATTAAAGTTATAAATGATGCTTATGGTGATGCA
ATAACTGAAGATTACGATATAATAGTTGTTACTCAAGAAACACTAAAAAATGCAGAGAAAATAAACAAAATAAGAGAGTC
TAAAGGATTAAAGCCATTAAAGATAGTTATCTTCAAACCTATATTAGCTGAAGATGGAAAGCCAATATCAACAACGAGGA
TTAGAAAGGGAGAGATAGATGAAGAGGGGAGAATAATAAAGTGA

Upstream 100 bases:

>100_bases
ACCTAATAAATGAGAAGGTTTTTAAACTCTCTGTTAAAGATATAGTTAATCTCTCAAATGAATTCTATAGATTTCTGCAA
AATAGGGGTAGGTTATAGCC

Downstream 100 bases:

>100_bases
TACCCATGGATGTTGTTTTAATTGTCTTAATTTTAGTTTTAGTTGGGTATTTTTCAAAAATCTTTGGGATTTTAAAAGAA
GAACATGCAAAGATTTTAAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKVVVGGTFDILHRGHKELLKFASSLGKLTIGITSDEFAKKYKTHKINDLKTRIENLKKFLDSIKADYEIKVINDAYGDA
ITEDYDIIVVTQETLKNAEKINKIRESKGLKPLKIVIFKPILAEDGKPISTTRIRKGEIDEEGRIIK

Sequences:

>Translated_147_residues
MKVVVGGTFDILHRGHKELLKFASSLGKLTIGITSDEFAKKYKTHKINDLKTRIENLKKFLDSIKADYEIKVINDAYGDA
ITEDYDIIVVTQETLKNAEKINKIRESKGLKPLKIVIFKPILAEDGKPISTTRIRKGEIDEEGRIIK
>Mature_147_residues
MKVVVGGTFDILHRGHKELLKFASSLGKLTIGITSDEFAKKYKTHKINDLKTRIENLKKFLDSIKADYEIKVINDAYGDA
ITEDYDIIVVTQETLKNAEKINKIRESKGLKPLKIVIFKPILAEDGKPISTTRIRKGEIDEEGRIIK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG1019

COG function: function code R; Predicted nucleotidyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic CoaD family

Homologues:

Organism=Caenorhabditis elegans, GI25143409, Length=129, Percent_Identity=34.8837209302326, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321716, Length=144, Percent_Identity=34.7222222222222, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24658602, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_METJA (Q58436)

Other databases:

- EMBL:   L77117
- PIR:   E64428
- RefSeq:   NP_248024.1
- ProteinModelPortal:   Q58436
- SMR:   Q58436
- GeneID:   1451927
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1030
- NMPDR:   fig|243232.1.peg.1061
- TIGR:   MJ1030
- HOGENOM:   HBG593121
- OMA:   ISTTRIR
- ProtClustDB:   PRK00777
- BioCyc:   MJAN243232:MJ_1030-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00647
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 16670; Mature: 16670

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVVGGTFDILHRGHKELLKFASSLGKLTIGITSDEFAKKYKTHKINDLKTRIENLKKF
CEEEECCCHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
LDSIKADYEIKVINDAYGDAITEDYDIIVVTQETLKNAEKINKIRESKGLKPLKIVIFKP
HHHHCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
ILAEDGKPISTTRIRKGEIDEEGRIIK
HHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVVVGGTFDILHRGHKELLKFASSLGKLTIGITSDEFAKKYKTHKINDLKTRIENLKKF
CEEEECCCHHHHHCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
LDSIKADYEIKVINDAYGDAITEDYDIIVVTQETLKNAEKINKIRESKGLKPLKIVIFKP
HHHHCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
ILAEDGKPISTTRIRKGEIDEEGRIIK
HHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087