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The map label for this gene is patS

Identifier: 15669158

GI number: 15669158

Start: 901995

End: 902816

Strand: Direct

Name: patS

Synonym: MJ0968

Alternate gene names: 15669158

Gene position: 901995-902816 (Clockwise)

Preceding gene: 15669156

Following gene: 15669161

Centisome position: 54.17

GC content: 31.63

Gene sequence:

>822_bases
ATGAAAGTGGCTATAGTGTTTGACAGTGCTGGGACTCTTGTAAAGATAATGAGAGTTATTAAAGATTTAAAGAAAAATAA
GTTTATTTGTAATAGCCAGACGGTTGATATAGTGGATAAAAAAAAGGGTAGAGCATTAGTTATAATTAAAGAAGACCCTT
TAAAGGTAGTGGATAAAGAAAATCCAGAAAAATTAATATCTGACTTATTAAAAGAGGTTGAAATTGGTATATCTTATTGT
AACCCACCGATAAATAGAGAAGGAATTTTCAAAGATAGAAAAACCAAGGTTAAAGAATTACAAGAGCCATTAAACATTTT
AAAGAGATATGAAGTAGAAACTGGGTATGGAAGTGCTTTAATAATAGACACTTATGCTGGAGAGGTTGAATACACAATAG
CAACAGCTGGATGTTTATTTAAAGAGGTTAAAGAAACAATTAAACAACTAAAAGATTTAGGAGTTAAGGTTTTCATTGCT
TCTGGAGATAGAAAAGGGTTTATAAAGAGATTAGCTGAAATTACTGGGGTTGATGAACGATATATAATGGCAGAGGCTCA
TCAGGAGTTAAAGAGAGATTTAATAAGAAATCTAAAAAAAGAGGGGTACTTTACAATAATGGTAGGGGATGGAGCTAACG
ATGTCCCAGCAATGATTGAAAGTGATTTAGCAGTGGTAACATTGCAAAATGGGAATGTTTCGAGGAGAGCTCTCGAAACA
GCTGATATAAAGATTTACAACATAAAGGAAATAGTTGATATATGTAAAAAAGTTATTAATGGAGAAATTAAAGGTAGAAT
GCAAATTAAGGAGTGTTCTTAA

Upstream 100 bases:

>100_bases
AGAAACTAAAGCTAAGGTTATTAATATCACTGCCAACCTCTTCATGCTCCCACAATAATTCTTTATATCTGAACGTATAT
ATTTAATTAATGGGGTAATT

Downstream 100 bases:

>100_bases
TATAAGACATTATTTATAGATTAAAATTAGCCATTTCGGAATGGAAATCTGTCTAAAATGTAGTGTTTCCATTTAAATGT
CTCAGTTAATTAAATCAGAC

Product: copper transporting P type ATPase CopA

Products: ADP; Phosphate; K(+)(In). [C]

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKENPEKLISDLLKEVEIGISYC
NPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSALIIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIA
SGDRKGFIKRLAEITGVDERYIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALET
ADIKIYNIKEIVDICKKVINGEIKGRMQIKECS

Sequences:

>Translated_273_residues
MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKENPEKLISDLLKEVEIGISYC
NPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSALIIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIA
SGDRKGFIKRLAEITGVDERYIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALET
ADIKIYNIKEIVDICKKVINGEIKGRMQIKECS
>Mature_273_residues
MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKENPEKLISDLLKEVEIGISYC
NPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSALIIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIA
SGDRKGFIKRLAEITGVDERYIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALET
ADIKIYNIKEIVDICKKVINGEIKGRMQIKECS

Specific function: Most probably acts as a phosphatase in the cytosol

COG id: COG4087

COG function: function code R; Soluble P-type ATPase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily

Homologues:

Organism=Escherichia coli, GI1786914, Length=119, Percent_Identity=33.6134453781513, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PATS_METJA (Q58378)

Other databases:

- EMBL:   L77117
- PIR:   H64420
- RefSeq:   NP_247963.1
- ProteinModelPortal:   Q58378
- SMR:   Q58378
- GeneID:   1451866
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0968
- NMPDR:   fig|243232.1.peg.1000
- TIGR:   MJ0968
- HOGENOM:   HBG545847
- OMA:   FDSAGTL
- ProtClustDB:   CLSK876407
- BioCyc:   MJAN243232:MJ_0968-MONOMER
- GO:   GO:0016020
- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR11939
- PRINTS:   PR00119

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: 3.6.3.12 [C]

Molecular weight: Translated: 30740; Mature: 30740

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: ACT_SITE 8-8

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKE
CEEEEEECCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCEEEEECCCCCEECCCC
NPEKLISDLLKEVEIGISYCNPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSAL
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIASGDRKGFIKRLAEITGVDER
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCHH
YIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALET
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCEEEEEEECCCCHHHHHHH
ADIKIYNIKEIVDICKKVINGEIKGRMQIKECS
CCEEEEEHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MKVAIVFDSAGTLVKIMRVIKDLKKNKFICNSQTVDIVDKKKGRALVIIKEDPLKVVDKE
CEEEEEECCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCEEEEECCCCCEECCCC
NPEKLISDLLKEVEIGISYCNPPINREGIFKDRKTKVKELQEPLNILKRYEVETGYGSAL
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IIDTYAGEVEYTIATAGCLFKEVKETIKQLKDLGVKVFIASGDRKGFIKRLAEITGVDER
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCHH
YIMAEAHQELKRDLIRNLKKEGYFTIMVGDGANDVPAMIESDLAVVTLQNGNVSRRALET
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCEEEEEEECCCCHHHHHHH
ADIKIYNIKEIVDICKKVINGEIKGRMQIKECS
CCEEEEEHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; K(+)(Out) [C]

Specific reaction: ATP + H2O + K(+)(Out) = ADP + Phosphate + K(+)(In). [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087; 10760521