Click here to switch to the map view.

The map label for this gene is hdrB2

Identifier: 15669054

GI number: 15669054

Start: 786559

End: 787446

Strand: Reverse

Name: hdrB2

Synonym: MJ0863

Alternate gene names: 15669054

Gene position: 787446-786559 (Counterclockwise)

Preceding gene: 15669055

Following gene: 15669053

Centisome position: 47.29

GC content: 37.39

Gene sequence:

>888_bases
ATGAAGTATGCGTTTTTCTTAGGATGTATTATGCCACACAGATACCCAGGAGTTGAGAAAGCTACAAAAATAGTTATGGA
AGAGTTAGGAGTAGAATTGGAATATATGCCAGGAGCTTCTTGCTGTCCAGCTCCAGGAGTCTTTGGTTCATTCGACCAAA
AAACATGGCTCACATTAGCAGCAAGAAACTTATGTATTGCTGAAGAAATGGGATTAGATATTGTAACTGTCTGTAACGGT
TGTTACGGTTCATTGTTTGAGGCAGCACACATATTACATGAGAATAAAGAGGCATTGGACTTTGTAAATGAAAAGTTGGA
TAAGATTGGCAAGCAATACAAAGGAACTATTAAAGTTAGACACTTTGCTGAGTTGATTTATAAAGACATTGGAGTAGATA
AAATAAAAGAGAAAGTTGTTAAGCCATTAGATGTTTTAAATGTTGCTATCCACTACGGTTGTCACTTCTTAAAACCAAGT
GATGTTAAACACTTAGATTCTCCAGAAAGACCTAAATTGTTAGAGGAGATTGTTGCAGCAACTGGAGCTAAACCAGTTAT
GTATAGGGATTATTTAATGTGCTGTGGAGCTGGAGGAGGAGTTAGAGCGAGATTCTTACCAACTGCATTAGATATGACAA
AAGAAAAAATAAGAAATATGCTTGAAGCAGGAGCTGATTGCACCGTCAATGTCTGTCCATTCTGCCACTTACAGTTTGAT
AGGGGGCAAGTAGAGATAAAAGAGAAGTTTGGTGAAGAATATAAACTTCCTGTTTTACACTTAAGTCAGTTGTTAGGTTT
GGCATTTGGAATGAAGCCAGAGGACTTAGCTGTTAGCGTCCATGCAATCCCAGTTGACCCAGTTTTAAAGAAATTGGGAA
TAGAATAA

Upstream 100 bases:

>100_bases
GACTGGGAAAAGATGGATTTAAAGGAGTAAATCCAATAAAATTAGAATTAAAATTAAACAATAAAAAATTAAAGGAAATA
ATAAGATTTTTGGTGATAAG

Downstream 100 bases:

>100_bases
ACCATTAGCATTTTATATTTAAATATTTTTTATTATTCATAATTTTTATTTTATTTCTTTTTTTAATATTTTTGATAAAG
TCAATACTAACTTTTTTATA

Product: heterodisulfide reductase subunit HdrB2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGLDIVTVCNG
CYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVRHFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPS
DVKHLDSPERPKLLEEIVAATGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFD
RGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE

Sequences:

>Translated_295_residues
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGLDIVTVCNG
CYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVRHFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPS
DVKHLDSPERPKLLEEIVAATGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFD
RGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE
>Mature_295_residues
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLAARNLCIAEEMGLDIVTVCNG
CYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVRHFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPS
DVKHLDSPERPKLLEEIVAATGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFD
RGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRB2_METJA (Q58273)

Other databases:

- EMBL:   L77117
- PIR:   G64407
- RefSeq:   NP_247858.1
- GeneID:   1451752
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0863
- NMPDR:   fig|243232.1.peg.895
- TIGR:   MJ0863
- HOGENOM:   HBG513215
- OMA:   HYGCHFL
- ProtClustDB:   CLSK876313
- BioCyc:   MJAN243232:MJ_0863-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017678
- InterPro:   IPR004017
- TIGRFAMs:   TIGR03288

Pfam domain/function: PF02754 CCG

EC number: =1.8.98.1

Molecular weight: Translated: 32789; Mature: 32789

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ARNLCIAEEMGLDIVTVCNGCYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVR
HHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
HFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPSDVKHLDSPERPKLLEEIVAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCHHHHHHHHHH
TGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFD
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEC
RGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure
MKYAFFLGCIMPHRYPGVEKATKIVMEELGVELEYMPGASCCPAPGVFGSFDQKTWLTLA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCHHHHHHH
ARNLCIAEEMGLDIVTVCNGCYGSLFEAAHILHENKEALDFVNEKLDKIGKQYKGTIKVR
HHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
HFAELIYKDIGVDKIKEKVVKPLDVLNVAIHYGCHFLKPSDVKHLDSPERPKLLEEIVAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCHHHHHHHHHH
TGAKPVMYRDYLMCCGAGGGVRARFLPTALDMTKEKIRNMLEAGADCTVNVCPFCHLQFD
CCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEC
RGQVEIKEKFGEEYKLPVLHLSQLLGLAFGMKPEDLAVSVHAIPVDPVLKKLGIE
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087