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The map label for this gene is yfdZ [C]

Identifier: 15668865

GI number: 15668865

Start: 611725

End: 612837

Strand: Reverse

Name: yfdZ [C]

Synonym: MJ0684

Alternate gene names: 15668865

Gene position: 612837-611725 (Counterclockwise)

Preceding gene: 15668867

Following gene: 15668864

Centisome position: 36.81

GC content: 31.72

Gene sequence:

>1113_bases
ATGCTATCAAAAAGGCTCTTAAATTTTGAATCATTTGAAGTTATGGATATTTTAGCATTAGCACAAAAATTAGAGAGTGA
AGGGAAGAAAGTTATACACTTAGAGATAGGAGAGCCAGATTTTAACACACCAAAACCTATTGTTGATGAAGGAATTAAAT
CTTTAAAAGAAGGAAAAACACACTATACCGACAGTAGAGGTATTTTAGAGTTAAGAGAGAAAATTAGTGAGCTATATAAA
GATAAATACAAGGCAGATATAATCCCAGATAACATAATCATTACTGGAGGGAGTTCTTTAGGGCTGTTTTTTGCTCTATC
TTCAATAATAGATGATGGAGATGAGGTTTTAATTCAAAATCCATGCTATCCATGCTATAAGAATTTTATCAGATTCTTAG
GAGCTAAGCCAGTGTTTTGTGATTTTACAGTTGAGAGCTTAGAGGAAGCTTTATCTGATAAAACAAAGGCTATAATTATA
AACTCTCCTTCAAACCCATTGGGAGAAGTTATAGATAGAGAGATTTATGAATTTGCCTATGAAAACATCCCTTATATAAT
CTCTGATGAAATCTACAATGGCTTAGTTTATGAAGGGAAATGCTATTCAGCAATTGAATTTGATGAAAATTTGGAAAAAA
CCATTTTAATTAATGGATTCTCTAAGTTGTATGCAATGACTGGGTGGAGAATAGGTTATGTTATATCTAACGATGAGATT
ATTGAAGCAATTTTAAAATTACAGCAGAATTTATTTATCTCTGCTCCAACCATATCTCAATATGCGGCATTAAAGGCGTT
TGAGAAAGAAACTGAAAGAGAAATAAACAGCATGATAAAAGAATTTGATAGAAGGAGGAGATTAGTTTTAAAATACGTTA
AAGATTTTGGATGGGAGGTTAATAATCCAATTGGAGCTTACTATGTATTTCCAAACATTGGAGAAGATGGAAGAGAGTTT
GCCTATAAATTATTGAAGGAGAAATTTGTTGCTCTAACTCCAGGAATAGGCTTTGGTAGTAAAGGGAAAAACTATATAAG
GATTAGCTATGCCAACTCCTATGAAAACATTAAAGAGGGTTTAGAGAGAATTAAGGAATTTTTAAACAAATAG

Upstream 100 bases:

>100_bases
ACTCCACCTTTTCCACTCACAGCAATAATCATTTTATGCCACCACGAAAAGTATTATTAATTAATAATAATTCCTTTTAG
TGTTTATAAATGGTGATGTC

Downstream 100 bases:

>100_bases
ATAAGCAAAAACTTTATAAGGGGCTAATAATGAATAGTAAAATAGAAATAATAAAAATTAAAGCTAAAAAACCTATTAAC
CCAACAAAGATACCCGGAGC

Product: aspartate aminotransferase AspB

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTHYTDSRGILELREKISELYK
DKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIII
NSPSNPLGEVIDREIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEI
IEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGREF
AYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFLNK

Sequences:

>Translated_370_residues
MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTHYTDSRGILELREKISELYK
DKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIII
NSPSNPLGEVIDREIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEI
IEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGREF
AYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFLNK
>Mature_370_residues
MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTHYTDSRGILELREKISELYK
DKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIII
NSPSNPLGEVIDREIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEI
IEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGREF
AYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFLNK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=31.2101910828025, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=31.2101910828025, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI95147551, Length=330, Percent_Identity=28.1818181818182, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI169881279, Length=330, Percent_Identity=28.1818181818182, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI169881281, Length=233, Percent_Identity=27.0386266094421, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=26.3707571801567, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI19263340, Length=370, Percent_Identity=26.2162162162162, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI215599424, Length=370, Percent_Identity=25.9459459459459, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=31.2169312169312, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=25.2688172043011, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=27.8645833333333, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790797, Length=364, Percent_Identity=26.3736263736264, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=28.8409703504043, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=24.8717948717949, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=25, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=369, Percent_Identity=26.5582655826558, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=24.5478036175711, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI28573069, Length=416, Percent_Identity=24.5192307692308, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24646114, Length=416, Percent_Identity=24.5192307692308, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573067, Length=416, Percent_Identity=24.5192307692308, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28573065, Length=416, Percent_Identity=24.5192307692308, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=26.3852242744063, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45551451, Length=367, Percent_Identity=26.7029972752044, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641770, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641760, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641768, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641766, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641764, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT2_METJA (Q58097)

Other databases:

- EMBL:   L77117
- RefSeq:   NP_247668.1
- PDB:   2Z61
- PDBsum:   2Z61
- ProteinModelPortal:   Q58097
- SMR:   Q58097
- GeneID:   1451550
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0684
- NMPDR:   fig|243232.1.peg.705
- TIGR:   MJ0684
- HOGENOM:   HBG645860
- OMA:   FFICANS
- ProtClustDB:   CLSK2517644
- BioCyc:   MJAN243232:MJ_0684-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 42348; Mature: 42348

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 37-37 BINDING 165-165 BINDING 347-347

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKT
CCCCHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCC
HYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQN
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEC
PCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIIINSPSNPLGEVIDREIYEFAY
CCCHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEI
HCCCEEEEHHHHCCEEECCCCCEEEECCCCCCCEEEEECHHHHHHHCCCEEEEEECCHHH
IEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEV
HHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NNPIGAYYVFPNIGEDGREFAYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCHHHHHHH
LERIKEFLNK
HHHHHHHHCC
>Mature Secondary Structure
MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKT
CCCCHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCC
HYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQN
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEC
PCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIIINSPSNPLGEVIDREIYEFAY
CCCHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEI
HCCCEEEEHHHHCCEEECCCCCEEEECCCCCCCEEEEECHHHHHHHCCCEEEEEECCHHH
IEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEV
HHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NNPIGAYYVFPNIGEDGREFAYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCHHHHHHH
LERIKEFLNK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087