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The map label for this gene is pheA [C]

Identifier: 15668421

GI number: 15668421

Start: 233695

End: 233994

Strand: Reverse

Name: pheA [C]

Synonym: MJ0246

Alternate gene names: 15668421

Gene position: 233994-233695 (Counterclockwise)

Preceding gene: 15668426

Following gene: 15668420

Centisome position: 14.05

GC content: 27.33

Gene sequence:

>300_bases
ATGATAGAGAAACTTGCTGAAATTAGGAAGAAGATTGATGAGATTGACAATAAGATATTAAAGCTAATTGCTGAAAGAAA
TAGTTTAGCTAAGGATGTAGCTGAGATAAAAAATCAGCTTGGTATTCCTATTAACGACCCAGAAAGAGAAAAATATATAT
ACGATAGAATAAGAAAACTTTGTAAAGAACATAACGTTGATGAAAATATTGGCATTAAAATATTTCAAATACTTATAGAG
CATAATAAAGCTCTCCAAAAGCAATATCTTGAGGAAACACAAAATAAAAACAAAAAATAA

Upstream 100 bases:

>100_bases
ATTGTCCATCTTTTGTTTTTATACATAAACAATACAAATAATATGGCGGATAACTTTATATATTTTATTTAAGTTTTTAT
AATAACATTCTGGGGTTACA

Downstream 100 bases:

>100_bases
TTAAAAATTAATAGAAAAATAATAAAAAAGGATAAGAAGGTGAGATGATGGGAAGGATTAGGCAGACATTAATTAAAAGA
ACAGCTATGGAATTAATTAA

Product: chorismate mutase

Products: prephenate

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MIEKLAEIRKKIDEIDNKILKLIAERNSLAKDVAEIKNQLGIPINDPEREKYIYDRIRKLCKEHNVDENIGIKIFQILIE
HNKALQKQYLEETQNKNKK

Sequences:

>Translated_99_residues
MIEKLAEIRKKIDEIDNKILKLIAERNSLAKDVAEIKNQLGIPINDPEREKYIYDRIRKLCKEHNVDENIGIKIFQILIE
HNKALQKQYLEETQNKNKK
>Mature_99_residues
MIEKLAEIRKKIDEIDNKILKLIAERNSLAKDVAEIKNQLGIPINDPEREKYIYDRIRKLCKEHNVDENIGIKIFQILIE
HNKALQKQYLEETQNKNKK

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG1605

COG function: function code E; Chorismate mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=92, Percent_Identity=34.7826086956522, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y246_METJA (Q57696)

Other databases:

- EMBL:   L77117
- PIR:   G64330
- RefSeq:   NP_247217.1
- PDB:   2GTV
- PDBsum:   2GTV
- ProteinModelPortal:   Q57696
- SMR:   Q57696
- DisProt:   DP00465
- GeneID:   1451100
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0246
- NMPDR:   fig|243232.1.peg.254
- TIGR:   MJ0246
- HOGENOM:   HBG726604
- OMA:   HHIEPEV
- ProtClustDB:   PRK06285
- BioCyc:   MJAN243232:MJ_0246-MONOMER
- InterPro:   IPR002701
- InterPro:   IPR010950
- InterPro:   IPR020822
- Gene3D:   G3DSA:1.20.59.10
- SMART:   SM00830
- TIGRFAMs:   TIGR01791

Pfam domain/function: PF01817 CM_2; SSF48600 Chorismate_mut

EC number: 5.4.99.5

Molecular weight: Translated: 11782; Mature: 11782

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS51168 CHORISMATE_MUT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKLAEIRKKIDEIDNKILKLIAERNSLAKDVAEIKNQLGIPINDPEREKYIYDRIRKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
CKEHNVDENIGIKIFQILIEHNKALQKQYLEETQNKNKK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIEKLAEIRKKIDEIDNKILKLIAERNSLAKDVAEIKNQLGIPINDPEREKYIYDRIRKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
CKEHNVDENIGIKIFQILIEHNKALQKQYLEETQNKNKK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: L-isoleucine; L-leucine; L-methionine [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate

Specific reaction: chorismate = prephenate

General reaction: elimination of H2O; C-O bond cleavage [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087