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The map label for this gene is ptr1

Identifier: 15668323

GI number: 15668323

Start: 146593

End: 147039

Strand: Direct

Name: ptr1

Synonym: MJ0151

Alternate gene names: 15668323

Gene position: 146593-147039 (Clockwise)

Preceding gene: 15668322

Following gene: 15668324

Centisome position: 8.8

GC content: 29.08

Gene sequence:

>447_bases
ATGCTTGATAGAATTGATTTAAAAATTCTAAGAATTTTAAATGGAAATGCCAGAAAATCATTTAGAGAAATTGGGAGAGA
ATTGGGTATTAGTGAGGGGACTGTAAGGAATAGAGTAAAAAGATTAACTGAAAAAGGAATCATAACAGGTTTTCATGCAT
CTATAAATCCAAAAAATTTGGGATTTGAAGTAGTTGCCATATTAGGTTTATATATTAAACCATCTAAGGTTGAAGAAACC
CTCAATAAATTAAAAGAGCTTGATGAAATAGTTGAACTCTATCAAACTACTGGAGAATATGATGCCGTTTGTATAGCAAT
TTTAAAGGATATAGAAAGCTTAGGAAAATTTTTAGCAGAGAAGATATATCCATTAGTTAATGTTAATGGATGTAAAGTAA
CTCTTGTTTTGAGAACATTTAAAGATGGTAGTAAGATGCCAATATAA

Upstream 100 bases:

>100_bases
AGAAGAAAAGTCAATGCTGTTGAAACAAAATGTTGTGGAAAGGGTGATGAGTACTGCGAATTTTTAGTAAAAATTGAAGA
TAAATTGTATTGGTGATTAA

Downstream 100 bases:

>100_bases
AATTTTATTACTAAATAATAAACAAAAAAATCAGATATTACTAAAAAAATCAAATAGAAACATTTAAAAAAGCCCTATTT
TTTATTTTGCAAGTCATAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNLGFEVVAILGLYIKPSKVEET
LNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAEKIYPLVNVNGCKVTLVLRTFKDGSKMPI

Sequences:

>Translated_148_residues
MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNLGFEVVAILGLYIKPSKVEET
LNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAEKIYPLVNVNGCKVTLVLRTFKDGSKMPI
>Mature_148_residues
MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNLGFEVVAILGLYIKPSKVEET
LNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAEKIYPLVNVNGCKVTLVLRTFKDGSKMPI

Specific function: Participates in positive as well as negative regulation of transcription. Binds to its own promoter

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790182, Length=139, Percent_Identity=34.5323741007194, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=28, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTR1_METJA (Q57615)

Other databases:

- EMBL:   L77117
- PIR:   H64318
- RefSeq:   NP_247119.1
- ProteinModelPortal:   Q57615
- SMR:   Q57615
- GeneID:   1450995
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0151
- NMPDR:   fig|243232.1.peg.156
- TIGR:   MJ0151
- HOGENOM:   HBG740878
- OMA:   ESINDEN
- ProtClustDB:   CLSK2517555
- BioCyc:   MJAN243232:MJ_0151-MONOMER
- GO:   GO:0005622
- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00033
- SMART:   SM00344

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 16633; Mature: 16633

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00519 HTH_ASNC_1; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNL
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCC
GFEVVAILGLYIKPSKVEETLNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KIYPLVNVNGCKVTLVLRTFKDGSKMPI
HHHHHCCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MLDRIDLKILRILNGNARKSFREIGRELGISEGTVRNRVKRLTEKGIITGFHASINPKNL
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCC
GFEVVAILGLYIKPSKVEETLNKLKELDEIVELYQTTGEYDAVCIAILKDIESLGKFLAE
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KIYPLVNVNGCKVTLVLRTFKDGSKMPI
HHHHHCCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11226165