Click here to switch to the map view.

The map label for this gene is yrbG [C]

Identifier: 15668262

GI number: 15668262

Start: 85705

End: 86613

Strand: Direct

Name: yrbG [C]

Synonym: MJ0091

Alternate gene names: 15668262

Gene position: 85705-86613 (Clockwise)

Preceding gene: 15668261

Following gene: 15668263

Centisome position: 5.15

GC content: 34.54

Gene sequence:

>909_bases
ATGCTAATTTTAGGGGTTGGTTATTTTCTATTAGGGCTTATTCTACTGTATTATGGGAGCGATTGGTTTGTCTTAGGAAG
TGAGAGGATAGCAAGGCATTTTAATGTGTCAAACTTTGTCATTGGAGCTACGGTTATGGCTATTGGAACATCTCTGCCAG
AGATATTAACATCTGCTTATGCTTCTTATATGCATGCTCCGGGCATATCAATAGGAAATGCCATTGGTTCTTGTATCTGC
AATATAGGTTTAGTCCTTGGCTTAAGTGCAATTATAAGTCCAATAATAGTTGATAAAAACTTACAAAAGAATATATTAGT
TTATCTTCTATTTGTTATATTTGCTGCAGTTATAGGAATTGATGGATTTTCATGGATTGATGGAGTTGTTTTGCTAATTT
TATTTATTATCTACTTAAGATGGACTGTAAAGAATGGAAGTGCTGAGATAGAAGAAAATAATGATAAAAACAACCCTTCA
GTAGTGTTCTCCTTAGTTTTGTTAATAATTGGGTTAATTGGTGTTTTAGTTGGAGCTGAATTATTTGTTGATGGAGCAAA
GAAGATAGCGTTAGCTTTAGATATATCTGATAAGGTTATTGGATTTACCTTAGTGGCATTTGGAACATCTCTACCAGAGT
TAATGGTTTCCTTAGCAGCAGCAAAGAGAAACCTTGGAGGCATGGTCTTAGGAAATGTCATTGGAAGTAACATAGCTGAT
ATTGGTGGCGCTTTGGCAGTTGGAAGTTTATTTATGCATCTCCCAGCGGAAAATGTACAAATGGCTGTGTTGGTAATTAT
GAGCCTTTTACTCTATTTATTTGCAAAATACTCAAAGATTGGTAGATGGCAAGGAATTTTATTTTTAGCTCTATATATAA
TTGCAATAGCTTCTTTGAGGATGGGATAA

Upstream 100 bases:

>100_bases
TATAAATACAATATGGATGAACTGAAAATTTTGCTTAAGTTTAAATATTATTGCAGAATATATTCAAAAACAAACTTTAA
TTAATTTAGTAGGGATAAGA

Downstream 100 bases:

>100_bases
TGATAAAGATAACAGTTAAGAGATTTAACGGAGAGAAAGAGTATCTTGAAAGCTATGAAGTCCCAGAAAATATAACAGTT
TTAGAGGCCTTAGAGTATAT

Product: Na+/Ca+ exchanger protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCIC
NIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPS
VVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIAD
IGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMG

Sequences:

>Translated_302_residues
MLILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCIC
NIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPS
VVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIAD
IGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMG
>Mature_302_residues
MLILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCIC
NIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPS
VVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIAD
IGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family

Homologues:

Organism=Escherichia coli, GI1789587, Length=304, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y091_METJA (Q57556)

Other databases:

- EMBL:   L77117
- PIR:   C64311
- RefSeq:   NP_247055.1
- ProteinModelPortal:   Q57556
- GeneID:   1450930
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0091
- NMPDR:   fig|243232.1.peg.92
- TIGR:   MJ0091
- HOGENOM:   HBG538237
- OMA:   HANIIVI
- ProtClustDB:   CLSK876065
- BioCyc:   MJAN243232:MJ_0091-MONOMER
- InterPro:   IPR004481
- InterPro:   IPR004837
- TIGRFAMs:   TIGR00367

Pfam domain/function: PF01699 Na_Ca_ex

EC number: NA

Molecular weight: Translated: 32213; Mature: 32213

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x406c8058)-; HASH(0x406cc270)-; HASH(0x406ce670)-; HASH(0xbf148cc)-; HASH(0x406bbd7c)-; HASH(0xb15f050)-; HASH(0x406cee44)-; HASH(0x406dab80)-; HASH(0xaf4cbbc)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAY
CEEEEHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
ASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
DGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPSVVFSLVLLIIGLIGVLVGAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIAD
HHHCCHHHEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
IGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MG
CH
>Mature Secondary Structure
MLILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAY
CEEEEHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
ASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
DGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPSVVFSLVLLIIGLIGVLVGAE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIAD
HHHCCHHHEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
IGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MG
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087