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The map label for this gene is rfk

Identifier: 15668227

GI number: 15668227

Start: 55756

End: 56166

Strand: Reverse

Name: rfk

Synonym: MJ0056

Alternate gene names: 15668227

Gene position: 56166-55756 (Counterclockwise)

Preceding gene: 15668228

Following gene: 15668226

Centisome position: 3.37

GC content: 28.95

Gene sequence:

>411_bases
TTGGTGAAATTGATGATTATTGAGGGAGAAGTAGTTTCAGGACTTGGAGAAGGGAGATATTTTTTATCCCTCCCTCCTTA
CAAAGAGATATTTAAGAAGATTCTTGGCTTTGAACCTTATGAGGGGACATTAAATTTAAAATTAGATAGAGAATTTGATA
TAAACAAATTTAAATATATTGAAACAGAGGATTTTGAATTTAATGGGAAAAGATTTTTTGGAGTTAAGGTTTTACCAATA
AAAATATTAATAGGTAATAAAAAAATAGATGGGGCGATAGTTGTGCCGAAAAAAACATATCATAGTAGTGAGATTATAGA
GATAATTGCCCCAATGAAACTTAGGGAGCAATTTAATTTAAAGGATGGAGATGTTATAAAAATACTAATTAAGGGAGATA
AAGATGAATAA

Upstream 100 bases:

>100_bases
CTTAGAGGCATCATGGGCTGGAATGTTGGCTTTGAAGTTGTTGGGAGAGTATAAACCAAAGTATAAAGAAGAATCCCACC
ATTAAAATTATTAAAATTTT

Downstream 100 bases:

>100_bases
TGTAGAAAAAGCCATAGAAGCATTAAAAAAAGGAGAAATAATTTTAGTTTATGACTCAGATGAGAGAGAAGGAGAAACGG
ACATGGTTGTTGCCTCCCAA

Product: riboflavin kinase

Products: NA

Alternate protein names: RFK; CTP-dependent riboflavin kinase; CTP:riboflavin 5'-phosphotransferase; Flavokinase

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MVKLMIIEGEVVSGLGEGRYFLSLPPYKEIFKKILGFEPYEGTLNLKLDREFDINKFKYIETEDFEFNGKRFFGVKVLPI
KILIGNKKIDGAIVVPKKTYHSSEIIEIIAPMKLREQFNLKDGDVIKILIKGDKDE

Sequences:

>Translated_136_residues
MVKLMIIEGEVVSGLGEGRYFLSLPPYKEIFKKILGFEPYEGTLNLKLDREFDINKFKYIETEDFEFNGKRFFGVKVLPI
KILIGNKKIDGAIVVPKKTYHSSEIIEIIAPMKLREQFNLKDGDVIKILIKGDKDE
>Mature_136_residues
MVKLMIIEGEVVSGLGEGRYFLSLPPYKEIFKKILGFEPYEGTLNLKLDREFDINKFKYIETEDFEFNGKRFFGVKVLPI
KILIGNKKIDGAIVVPKKTYHSSEIIEIIAPMKLREQFNLKDGDVIKILIKGDKDE

Specific function: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, but cannot use neither ATP nor GTP

COG id: COG1339

COG function: function code KH; Transcriptional regulator of a riboflavin/FAD biosynthetic operon

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal riboflavin kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIFK_METJA (Q60365)

Other databases:

- EMBL:   L77117
- PIR:   H64306
- RefSeq:   NP_247020.1
- PDB:   2OYN
- PDB:   2P3M
- PDB:   2VBS
- PDB:   2VBT
- PDB:   2VBU
- PDB:   2VBV
- PDBsum:   2OYN
- PDBsum:   2P3M
- PDBsum:   2VBS
- PDBsum:   2VBT
- PDBsum:   2VBU
- PDBsum:   2VBV
- ProteinModelPortal:   Q60365
- SMR:   Q60365
- GeneID:   1450895
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0056
- NMPDR:   fig|243232.1.peg.57
- TIGR:   MJ0056
- HOGENOM:   HBG553349
- OMA:   PYEGTLN
- ProtClustDB:   PRK14132
- BioCyc:   MetaCyc:MONOMER-13864
- BioCyc:   MJAN243232:MJ_0056-MONOMER
- HAMAP:   MF_01285
- InterPro:   IPR015865
- InterPro:   IPR002834
- Gene3D:   G3DSA:2.40.30.30

Pfam domain/function: PF01982 CTP-dep_RFKase

EC number: =2.7.1.161

Molecular weight: Translated: 15686; Mature: 15686

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: BINDING 99-99 BINDING 100-100 BINDING 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLMIIEGEVVSGLGEGRYFLSLPPYKEIFKKILGFEPYEGTLNLKLDREFDINKFKYI
CEEEEEECCCEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEE
ETEDFEFNGKRFFGVKVLPIKILIGNKKIDGAIVVPKKTYHSSEIIEIIAPMKLREQFNL
ECCCCEECCCEEEEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCEEECCCHHHHHHCCC
KDGDVIKILIKGDKDE
CCCCEEEEEEECCCCC
>Mature Secondary Structure
MVKLMIIEGEVVSGLGEGRYFLSLPPYKEIFKKILGFEPYEGTLNLKLDREFDINKFKYI
CEEEEEECCCEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEE
ETEDFEFNGKRFFGVKVLPIKILIGNKKIDGAIVVPKKTYHSSEIIEIIAPMKLREQFNL
ECCCCEECCCEEEEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCEEECCCHHHHHHCCC
KDGDVIKILIKGDKDE
CCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087