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The map label for this gene is ycgO [C]

Identifier: 15668228

GI number: 15668228

Start: 56182

End: 57462

Strand: Reverse

Name: ycgO [C]

Synonym: MJ0057

Alternate gene names: 15668228

Gene position: 57462-56182 (Counterclockwise)

Preceding gene: 15668229

Following gene: 15668227

Centisome position: 3.45

GC content: 34.04

Gene sequence:

>1281_bases
ATGGAACTTATGATGGCTATTGGTTACCTTGGATTAGCTTTAGTTCTTGGTTCGTTAGTGGCAAAAATTGCTGAAAAGTT
AAAAATTCCAGATATACCGTTATTGTTATTGTTAGGTTTAATCATAGGGCCTTTTTTACAAATCATCCCATCAGATTCAG
CAATGGAGATTTTTGAATATGCGGGACCGATAGGATTAATATTTATTTTGTTGGGAGGAGCATTTACAATGAGGATTTCA
CTACTTAAGAGAGTTATAAAAACAGTAGTGAGGTTAGATACAATAACATTTTTAATTACTCTACTTATTTCTGGTTTTAT
TTTTAATATGGTCTTAAATCTTCCATATACATCCCCAGTTGGCTATTTATTTGGAGCAATAACTGCTGCTACAGACCCAG
CAACTTTAATTCCAGTGTTTTCAAGAGTTAGAACAAATCCTGAAGTAGCTATAACGTTAGAGGCGGAGAGTATCTTTAAC
GACCCATTGGGAATAGTTTCAACCAGTGTTATTTTGGGGTTGTTTGGTTTATTTTCCTCATCAAATCCATTAATTGATTT
AATTACACTTGCTGGTGGAGCCATAGTTGTTGGCTTATTGTTAGCTAAAATATATGAAAAAATTATTATACATTGTGACT
TCCATGAGTATGTGGCTCCATTAGTTCTTGGAGGAGCAATGCTCCTTTTATATGTGGGAGATGATTTATTGCCAAGTATT
TGTGGTTATGGATTTAGTGGTTATATGGCTGTTGCAATAATGGGACTTTACTTGGGAGATGCATTATTTAGAGCGGATGA
TATAGATTATAAATATATAGTATCGTTCTGTGATGATTTATCTTTGTTGGCAAGAGTGTTTATTTTTGTATTTTTGGGAG
CATGTATAAAGCTAAGCATGTTAGAAAATTATTTCATTCCAGGTTTGTTAGTAGCTCTTGGCTCTATATTCTTAGCAAGA
CCTCTTGGGGTCTTCTTGGGTTTGATAGGTTCAAAACATTCATTTAAAGAAAAACTCTATTTTGCCTTAGAGGGACCAAG
AGGTGTTGTTCCTGCCGCTTTAGCTGTAACTGTTGGTATAGAAATATTGAAAAATGCTGATAAGATTCCAGCATCTATAA
CAAAATATATTACTCCAACAGATATTGCAGGAACAATAATCATTGGAACATTTATGACAATTTTATTGAGTGTTATCTTA
GAGGCATCATGGGCTGGAATGTTGGCTTTGAAGTTGTTGGGAGAGTATAAACCAAAGTATAAAGAAGAATCCCACCATTA
A

Upstream 100 bases:

>100_bases
TTCCTTTTTTTAATCTCCAATTATTTTCCTCGATAAAATATTTATATGATTTTTAGATTTTAAATATTCAGCCAAAAAGA
TAATTTTATATTGTGATAAC

Downstream 100 bases:

>100_bases
AATTATTAAAATTTTTTGGTGAAATTGATGATTATTGAGGGAGAAGTAGTTTCAGGACTTGGAGAAGGGAGATATTTTTT
ATCCCTCCCTCCTTACAAAG

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: MjNhaP1

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEYAGPIGLIFILLGGAFTMRIS
LLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPVGYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFN
DPLGIVSTSVILGLFGLFSSSNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSI
CGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLENYFIPGLLVALGSIFLAR
PLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVIL
EASWAGMLALKLLGEYKPKYKEESHH

Sequences:

>Translated_426_residues
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEYAGPIGLIFILLGGAFTMRIS
LLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPVGYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFN
DPLGIVSTSVILGLFGLFSSSNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSI
CGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLENYFIPGLLVALGSIFLAR
PLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVIL
EASWAGMLALKLLGEYKPKYKEESHH
>Mature_426_residues
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEYAGPIGLIFILLGGAFTMRIS
LLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPVGYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFN
DPLGIVSTSVILGLFGLFSSSNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSI
CGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLENYFIPGLLVALGSIFLAR
PLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVIL
EASWAGMLALKLLGEYKPKYKEESHH

Specific function: This is a Na(+)/H(+) antiporter. Can also transport lithium

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

Homologues:

Organism=Escherichia coli, GI87081854, Length=308, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAH1_METJA (Q60362)

Other databases:

- EMBL:   L77117
- PIR:   A64307
- RefSeq:   NP_247021.1
- ProteinModelPortal:   Q60362
- GeneID:   1450896
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0057
- NMPDR:   fig|243232.1.peg.58
- TIGR:   MJ0057
- HOGENOM:   HBG726978
- OMA:   HEYVAPL
- ProtClustDB:   CLSK876053
- BioCyc:   MJAN243232:MJ_0057-MONOMER
- InterPro:   IPR006153

Pfam domain/function: PF00999 Na_H_Exchanger

EC number: NA

Molecular weight: Translated: 45967; Mature: 45967

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xaf8be74)-; HASH(0xadeea60)-; HASH(0xaf40528)-; HASH(0xb209ba8)-; HASH(0xb5cbdf0)-; HASH(0xbb35f1c)-; HASH(0xae1226c)-; HASH(0xb1fe5b0)-; HASH(0xadeebe0)-; HASH(0xbb7ca80)-; HASH(0xaf7b41c)-; HASH(0xbcb6630)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AGPIGLIFILLGGAFTMRISLLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFNDPLGIVSTSVILGLFGLFSS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCC
SNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSI
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCHHHHHHH
CGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSM
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENYFIPGLLVALGSIFLARPLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
EILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVILEASWAGMLALKLLGEYKPKY
HHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KEESHH
CCCCCH
>Mature Secondary Structure
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEY
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AGPIGLIFILLGGAFTMRISLLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFNDPLGIVSTSVILGLFGLFSS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCC
SNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSI
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHCHHHHHHH
CGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSM
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENYFIPGLLVALGSIFLARPLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCHHHHHHHHHHH
EILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVILEASWAGMLALKLLGEYKPKY
HHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KEESHH
CCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087