Click here to switch to the map view.

The map label for this gene is yebU [C]

Identifier: 15668197

GI number: 15668197

Start: 27134

End: 27958

Strand: Reverse

Name: yebU [C]

Synonym: MJ0026

Alternate gene names: 15668197

Gene position: 27958-27134 (Counterclockwise)

Preceding gene: 15668198

Following gene: 15668196

Centisome position: 1.68

GC content: 27.64

Gene sequence:

>825_bases
TTGATGATTGTCTATAAAGGGGAGAAAATGCAATTTATAAGAGTTAATACTCTAAAGATTAATCCAGAAGTATTGAAAAA
AAGATTAGAAAATAAAGGTGTTGTTTTAGAAAAAACTTTCTTAGATTATGCTTTTGAAGTAAAGAAATCTCCTTTCTCAA
TTGGTTCTACTCCAGAGTATTTGTTTGGCTATTATATGCCTCAATCAATATCTTCAATGATTCCGCCGATTGTTTTAAAT
CCAAGAGAAGATGATTTTATCTTAGATATGTGTGCCGCTCCAGGAGGGAAAACAACTCATTTAGCCCAATTAATGAAAAA
TAAAGGGACAATAGTTGCAGTTGAAATTAGCAAAACAAGAACAAAGGCATTAAAATCAAATATAAATAGGATGGGAGTTT
TAAACACTATTATAATAAATGCAGATATGAGAAAATATAAAGATTACTTATTAAAAAATGAGATATTTTTTGATAAGATT
TTATTAGATGCCCCATGCTCAGGAAATATTATTAAAGATAAAAACAGAAACGTCTCAGAGGAAGACATAAAATACTGCTC
TTTAAGGCAGAAGGAGTTGATAGATATAGGTATAGATTTATTAAAAAAAGATGGAGAGTTAGTTTATTCAACCTGCTCAA
TGGAAGTTGAAGAAAATGAGGAAGTGATAAAATATATTCTACAAAAAAGAAATGATGTTGAGTTAATAATTATAAAAGCA
AATGAATTTAAAGGAATTAATATAAAAGAGGGATATATAAAAGGAACTTTAAGAGTTTTTCCACCAAATGAACCATTTTT
TATTGCAAAATTGAGAAAAATATAA

Upstream 100 bases:

>100_bases
TTGAAAAATATAGACACTCATCAAATAAATCCCACTTATAAATAGGAAGTAATATAAAAGCCCTTTGGGCTTTTATCAAT
ACCTTATTAAATAATAAAGT

Downstream 100 bases:

>100_bases
TTGGTGATGAGATGGATTTTATTGTTATTGATGGAAGTTACTTAGAAGGAGGAGGGCAGATTATAAGAACTGCTGTTTCT
TTATCAGCTTTAACTCAAAA

Product: proliferating cell nuclear antigen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MMIVYKGEKMQFIRVNTLKINPEVLKKRLENKGVVLEKTFLDYAFEVKKSPFSIGSTPEYLFGYYMPQSISSMIPPIVLN
PREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVEISKTRTKALKSNINRMGVLNTIIINADMRKYKDYLLKNEIFFDKI
LLDAPCSGNIIKDKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIKYILQKRNDVELIIIKA
NEFKGINIKEGYIKGTLRVFPPNEPFFIAKLRKI

Sequences:

>Translated_274_residues
MMIVYKGEKMQFIRVNTLKINPEVLKKRLENKGVVLEKTFLDYAFEVKKSPFSIGSTPEYLFGYYMPQSISSMIPPIVLN
PREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVEISKTRTKALKSNINRMGVLNTIIINADMRKYKDYLLKNEIFFDKI
LLDAPCSGNIIKDKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIKYILQKRNDVELIIIKA
NEFKGINIKEGYIKGTLRVFPPNEPFFIAKLRKI
>Mature_274_residues
MMIVYKGEKMQFIRVNTLKINPEVLKKRLENKGVVLEKTFLDYAFEVKKSPFSIGSTPEYLFGYYMPQSISSMIPPIVLN
PREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVEISKTRTKALKSNINRMGVLNTIIINADMRKYKDYLLKNEIFFDKI
LLDAPCSGNIIKDKNRNVSEEDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIKYILQKRNDVELIIIKA
NEFKGINIKEGYIKGTLRVFPPNEPFFIAKLRKI

Specific function: May act as RNA methyltransferase

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family

Homologues:

Organism=Homo sapiens, GI76150625, Length=287, Percent_Identity=41.1149825783972, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI76150623, Length=287, Percent_Identity=41.1149825783972, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI32698918, Length=185, Percent_Identity=35.6756756756757, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI39995082, Length=200, Percent_Identity=33.5, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI301336155, Length=200, Percent_Identity=33.5, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI270288818, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI23199998, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI8922322, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI270288816, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI11545785, Length=190, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081985, Length=274, Percent_Identity=35.7664233576642, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI2367212, Length=267, Percent_Identity=31.4606741573034, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17536757, Length=287, Percent_Identity=36.2369337979094, Blast_Score=166, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25143471, Length=173, Percent_Identity=31.2138728323699, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=252, Percent_Identity=27.3809523809524, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115534021, Length=177, Percent_Identity=31.0734463276836, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=281, Percent_Identity=40.5693950177936, Blast_Score=185, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6319447, Length=190, Percent_Identity=35.7894736842105, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324306, Length=275, Percent_Identity=25.0909090909091, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI22024126, Length=287, Percent_Identity=36.9337979094077, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21356513, Length=231, Percent_Identity=31.6017316017316, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24668781, Length=231, Percent_Identity=31.6017316017316, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355201, Length=205, Percent_Identity=30.2439024390244, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19920494, Length=173, Percent_Identity=28.3236994219653, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356579, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y026_METJA (Q60343)

Other databases:

- EMBL:   L77117
- PIR:   B64303
- RefSeq:   NP_246989.1
- PDB:   3A4T
- PDB:   3AJD
- PDBsum:   3A4T
- PDBsum:   3AJD
- ProteinModelPortal:   Q60343
- SMR:   Q60343
- GeneID:   1450864
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0026
- NMPDR:   fig|243232.1.peg.26
- TIGR:   MJ0026
- HOGENOM:   HBG726909
- OMA:   YLACNEM
- ProtClustDB:   CLSK876038
- BioCyc:   MJAN243232:MJ_0026-MONOMER
- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023
- TIGRFAMs:   TIGR00446

Pfam domain/function: PF01189 Nol1_Nop2_Fmu

EC number: NA

Molecular weight: Translated: 31491; Mature: 31491

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: ACT_SITE 212-212 BINDING 115-115 BINDING 142-142 BINDING 163-163

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIVYKGEKMQFIRVNTLKINPEVLKKRLENKGVVLEKTFLDYAFEVKKSPFSIGSTPEY
CEEEEECCEEEEEEEEEEEECHHHHHHHHHCCCEEEEEHHHHHHHEECCCCCCCCCCHHH
LFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVEISKTR
HHEECCHHHHHHHCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECHHH
TKALKSNINRMGVLNTIIINADMRKYKDYLLKNEIFFDKILLDAPCSGNIIKDKNRNVSE
HHHHHHCHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCH
EDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIKYILQKRNDVELIIIKA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHCCCCEEEEEEEC
NEFKGINIKEGYIKGTLRVFPPNEPFFIAKLRKI
CCCCCCCEECCEEEEEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MMIVYKGEKMQFIRVNTLKINPEVLKKRLENKGVVLEKTFLDYAFEVKKSPFSIGSTPEY
CEEEEECCEEEEEEEEEEEECHHHHHHHHHCCCEEEEEHHHHHHHEECCCCCCCCCCHHH
LFGYYMPQSISSMIPPIVLNPREDDFILDMCAAPGGKTTHLAQLMKNKGTIVAVEISKTR
HHEECCHHHHHHHCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECHHH
TKALKSNINRMGVLNTIIINADMRKYKDYLLKNEIFFDKILLDAPCSGNIIKDKNRNVSE
HHHHHHCHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCH
EDIKYCSLRQKELIDIGIDLLKKDGELVYSTCSMEVEENEEVIKYILQKRNDVELIIIKA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHCCCCEEEEEEEC
NEFKGINIKEGYIKGTLRVFPPNEPFFIAKLRKI
CCCCCCCEECCEEEEEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087