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The map label for this gene is mtgA

Identifier: 30995405

GI number: 30995405

Start: 881500

End: 882240

Strand: Direct

Name: mtgA

Synonym: HI0831

Alternate gene names: 30995405

Gene position: 881500-882240 (Clockwise)

Preceding gene: 16272771

Following gene: 161350024

Centisome position: 48.17

GC content: 35.36

Gene sequence:

>741_bases
TTGAAAAAAACTAAGCGAATTTTTACCGCACTTTCTCACTTATTTAGTCCTAAATGGTGGAAAAAAAACTGGCAGCGAGT
TGTCTTTTGTTTTTTTTTCGCCGTTTTTGCTTTGTTGCTGATTTTTCGCTTTGTACCTATTCCATTTTCCGCTTATATGG
TACAACAAAAAATCGCTAATCTTTTACAAGGTGATTTTCGATATCAAATCCAATATAACTGGGTTAGCCTAGAAAATATC
TCTCCAAACATTCAATTAGCTGTGATTTCATCAGAAGATCAGCGTTTTCTTGAACATTTAGGCTTTGATTTTGAGGCTAT
CCAACGAGCAATTCGGTATAACGAAAAATCTAACAAAGGAATCCGAGGGGCATCAACTATTTCCCAGCAAACTGCTAAAA
ACTTAATGCTTTGGCACGGACAAAATTGGCTACGAAAAGGTTTAGAAGTTCCAGCGACTATGTTGCTTGAGCTGACTTGG
TCGAAAAAACGTATTTTAGAAGTGTATTTAAATATTGCGGAATTTGGAAACGGCATTTTTGGTGTGGAAGCGGCAAGTCG
CTATTACTTTAAAAAATCAGCTAAAAATTTATCTCAAAATGAAGCCGCACTTTTAGCTGCTGTGTTGCCCAATCCAATCA
TTTATAAAGTAAATAAGCCAAGCTTATTAGTTCGTAAAAAACAAACTTGGATTTTGAGACAAATGGGAAATTTAGGCACT
GAATACTTGAGCCATTTATAA

Upstream 100 bases:

>100_bases
AATCTGAATACAAGTGCCGCCACAATCACTCGAGGTTCCAATATGATTAAAACGATGGATCCTGATTTTATGCAATGGAT
GAAACAACATCTTGATCTCA

Downstream 100 bases:

>100_bases
AAAATGCAATCGAATTTCTAAAGTACAACAAACTAAAAAATATTTACTTAATACACAAAATAAAAAACGAGTCTAAGACT
CGGTTTTTTATTTATAACAT

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKTKRIFTALSHLFSPKWWKKNWQRVVFCFFFAVFALLLIFRFVPIPFSAYMVQQKIANLLQGDFRYQIQYNWVSLENI
SPNIQLAVISSEDQRFLEHLGFDFEAIQRAIRYNEKSNKGIRGASTISQQTAKNLMLWHGQNWLRKGLEVPATMLLELTW
SKKRILEVYLNIAEFGNGIFGVEAASRYYFKKSAKNLSQNEAALLAAVLPNPIIYKVNKPSLLVRKKQTWILRQMGNLGT
EYLSHL

Sequences:

>Translated_246_residues
MKKTKRIFTALSHLFSPKWWKKNWQRVVFCFFFAVFALLLIFRFVPIPFSAYMVQQKIANLLQGDFRYQIQYNWVSLENI
SPNIQLAVISSEDQRFLEHLGFDFEAIQRAIRYNEKSNKGIRGASTISQQTAKNLMLWHGQNWLRKGLEVPATMLLELTW
SKKRILEVYLNIAEFGNGIFGVEAASRYYFKKSAKNLSQNEAALLAAVLPNPIIYKVNKPSLLVRKKQTWILRQMGNLGT
EYLSHL
>Mature_246_residues
MKKTKRIFTALSHLFSPKWWKKNWQRVVFCFFFAVFALLLIFRFVPIPFSAYMVQQKIANLLQGDFRYQIQYNWVSLENI
SPNIQLAVISSEDQRFLEHLGFDFEAIQRAIRYNEKSNKGIRGASTISQQTAKNLMLWHGQNWLRKGLEVPATMLLELTW
SKKRILEVYLNIAEFGNGIFGVEAASRYYFKKSAKNLSQNEAALLAAVLPNPIIYKVNKPSLLVRKKQTWILRQMGNLGT
EYLSHL

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=215, Percent_Identity=56.2790697674419, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI87082258, Length=138, Percent_Identity=39.1304347826087, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786343, Length=145, Percent_Identity=33.7931034482759, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788867, Length=136, Percent_Identity=38.9705882352941, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_HAEIN (P44890)

Other databases:

- EMBL:   L42023
- PIR:   B64159
- RefSeq:   NP_438991.2
- ProteinModelPortal:   P44890
- SMR:   P44890
- GeneID:   949845
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0831
- TIGR:   HI_0831
- HOGENOM:   HBG685698
- OMA:   RQMSQLG
- ProtClustDB:   PRK00056
- BioCyc:   HINF71421:HI_0831-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 28700; Mature: 28700

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xda1cd34)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTKRIFTALSHLFSPKWWKKNWQRVVFCFFFAVFALLLIFRFVPIPFSAYMVQQKIAN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLQGDFRYQIQYNWVSLENISPNIQLAVISSEDQRFLEHLGFDFEAIQRAIRYNEKSNKG
HHCCCEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC
IRGASTISQQTAKNLMLWHGQNWLRKGLEVPATMLLELTWSKKRILEVYLNIAEFGNGIF
CCCHHHHHHHHHHHHEEECCCHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEE
GVEAASRYYFKKSAKNLSQNEAALLAAVLPNPIIYKVNKPSLLVRKKQTWILRQMGNLGT
EHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHH
EYLSHL
HHHHCH
>Mature Secondary Structure
MKKTKRIFTALSHLFSPKWWKKNWQRVVFCFFFAVFALLLIFRFVPIPFSAYMVQQKIAN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLQGDFRYQIQYNWVSLENISPNIQLAVISSEDQRFLEHLGFDFEAIQRAIRYNEKSNKG
HHCCCEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC
IRGASTISQQTAKNLMLWHGQNWLRKGLEVPATMLLELTWSKKRILEVYLNIAEFGNGIF
CCCHHHHHHHHHHHHEEECCCHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEE
GVEAASRYYFKKSAKNLSQNEAALLAAVLPNPIIYKVNKPSLLVRKKQTWILRQMGNLGT
EHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHH
EYLSHL
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800