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The map label for this gene is mdaB

Identifier: 30995393

GI number: 30995393

Start: 692495

End: 693073

Strand: Reverse

Name: mdaB

Synonym: HI0648

Alternate gene names: 30995393

Gene position: 693073-692495 (Counterclockwise)

Preceding gene: 16272592

Following gene: 16272590

Centisome position: 37.87

GC content: 44.04

Gene sequence:

>579_bases
ATGAATATTTTATTATTAGACGGCGGTAAGGCGTTTGGTCATTCTCACGGCGAGTTGAACCACACGCTTCACAAAAAAGC
GAAAGAAGTTTTGACCGCACTTGGACACAATGTCAAAGAAACTGTAATTGATGCTGGTTATGACGTTGAAGCTGAAATCG
AAAAATTCTTGTGGATGGATGCCGTGATTTGGCAAATGCCGAGCTGGTGGATGCATGAGCCTTGGACAGTGAAAAAATAC
ATAGACGAAGTATTAACCAATGGGCACGGCAAGTTATATCACAGTGATGGCAGACACAGCGTTAATCCAACCGAGGGCTA
TGGCACAGGCGGCTTGTTGCAAGGAAAAAAACACATGCTTTCACTGACTTGGAATGCACCGATTGAAGCCTTTACTCGCG
AAGGCGATTTCTTTGAAGGCAAAGGCGTGGATGTTTTGTATATGCATTTCCACAAACTCAACGAGTTCCTCGGTTTGACT
CGCCTGCCGACATTCTTATGTAACGATGTGGTTAAAAGTCCGCAAGTAGAACAATACTTAGCAGACTACCAAGCACACTT
GGAAAAAGTGTTCGGCTAA

Upstream 100 bases:

>100_bases
GAAATAACGTGGCAGACAAATATACTTTTAAAAATTAACGTAAAAAGGCATAATGGCAACCCCATTTTTTTTTATAATTA
TTTGTTTTAGGAGCAAAAAG

Downstream 100 bases:

>100_bases
TAAAAAAATCCATCTTCAATACGAAGATGGATTTTTTGTTTATTTCGTTAAGATTCGTTCAGAATCTACCAAGTTTTTTG
GGCAACCAAGGCTTACAAAG

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNILLLDGGKAFGHSHGELNHTLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKY
IDEVLTNGHGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLT
RLPTFLCNDVVKSPQVEQYLADYQAHLEKVFG

Sequences:

>Translated_192_residues
MNILLLDGGKAFGHSHGELNHTLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKY
IDEVLTNGHGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLT
RLPTFLCNDVVKSPQVEQYLADYQAHLEKVFG
>Mature_192_residues
MNILLLDGGKAFGHSHGELNHTLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDAVIWQMPSWWMHEPWTVKKY
IDEVLTNGHGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLT
RLPTFLCNDVVKSPQVEQYLADYQAHLEKVFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c

Homologues:

Organism=Escherichia coli, GI1789406, Length=191, Percent_Identity=58.1151832460733, Blast_Score=244, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDAB_HAEIN (P44803)

Other databases:

- EMBL:   L42023
- PIR:   C64084
- RefSeq:   NP_438808.2
- ProteinModelPortal:   P44803
- SMR:   P44803
- GeneID:   949679
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0648
- NMPDR:   fig|71421.1.peg.618
- TIGR:   HI_0648
- HOGENOM:   HBG289856
- OMA:   PTFICND
- ProtClustDB:   CLSK878255
- BioCyc:   HINF71421:HI_0648-MONOMER
- InterPro:   IPR003680

Pfam domain/function: PF02525 Flavodoxin_2

EC number: NA

Molecular weight: Translated: 21876; Mature: 21876

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLLDGGKAFGHSHGELNHTLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMD
CEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
AVIWQMPSWWMHEPWTVKKYIDEVLTNGHGKLYHSDGRHSVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLTRLPTFLCNDVVKSPQVEQYL
EEEECCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ADYQAHLEKVFG
HHHHHHHHHHCC
>Mature Secondary Structure
MNILLLDGGKAFGHSHGELNHTLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMD
CEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
AVIWQMPSWWMHEPWTVKKYIDEVLTNGHGKLYHSDGRHSVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKLNEFLGLTRLPTFLCNDVVKSPQVEQYL
EEEECCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ADYQAHLEKVFG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800