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The map label for this gene is rlmM [H]

Identifier: 16273647

GI number: 16273647

Start: 1260994

End: 1262085

Strand: Direct

Name: rlmM [H]

Synonym: HI1195m

Alternate gene names: 16273647

Gene position: 1260994-1262085 (Clockwise)

Preceding gene: 16273646

Following gene: 16273116

Centisome position: 68.9

GC content: 38.46

Gene sequence:

>1092_bases
ATGAATAAACTCGCATTATATTGTCGCCCAGGTTTTGAGAAAGAAGTCGCCGCAGAGATTACCGATCAAGCAAGTCATTT
AGGTGTATTTGGTTTTGCTCGAGTGCAAGATAATTCGGGCTACGTGATTTTTGAATGTTATCAACCTGATGAGGCAGATC
GCCTTGCCCGAGACATTCCTTTTAATCGTTTGATTTTTGCTCGTCAGATGATGGTTATTTCCGATTTATTGGAAGATTTA
GATCCTGCTGATCGTATTAGTCCCATCGTGGTGGCGTTTGAAGAATTATCACAACAAGTTAATTTTGCTCAATCTAGCGA
GCTTTTTGTAGAAACTGCAGATACAAATGAAGCGAAGGAGCTTTCCACTTTTTGTCGTAAATTTACCGTGCCTTTACGTC
AGGCATTGAAAAAACAAGGTTGGCTTTCGGCAAAGGCGAGTCAAAAGTGCGGTCAATTTTTACATTGTTTTTTTGTAAAA
CCGAATTGCTGTTATGTGGGATATTCTTATGTGGATAATCATTCCTCCCATTTTATGGGAATCCCTCGTTTAAAATTTCC
TGCAGATGCGCCGAGTCGCTCCACGTTAAAACTAGAAGAAGCTATTTTGACTTTTATTCCGCGTAAAGAAGAGAATAAAC
GTTTAAATGAAAATATGATTGGCGTTGATTTAGGGGCTTGCCCTGGTGGTTGGACGTATCAATTAGTTAAACGCGGTTTA
TTTGTTTATGCTGTTGATCACGGAAAAATGGCGGCGAGTTTGCATGATACGGGGCGCATTGAACATTGCGCGGAAGATGG
TTTTAAATTTCAGCCTCCCAAAAGGAAAAAAGTAGATTGGTTAGTCTGTGATATGGTGGAACAACCAAGTCGTATTTCTT
TATTGATTGGTAAATGGTTGTTGAATGGTTGGTGCCGAGAAACCATCTTCAATTTAAAATTACCCATGAAAAAACGTTAT
CAAGAAGTGATATTATGTTTAGAAAACTTGGCTGTTATGTTGGCTGAGCAGAATTTAAATTTTGATATCCAAGCAAAACA
TTTATATCACGATCGTGAAGAAATCACGGTTCATATAGCATTAAAACCTTGA

Upstream 100 bases:

>100_bases
CCAAAATCATTTTATGTGGTCAATCATCTTGATCGCCTTGATGACCAAAAAATTCAAGCATTCCGTCAGTGGATTATTAA
CTCAATTAAACAAGAAGAAA

Downstream 100 bases:

>100_bases
GTGAACTGTTTTCATAACCAAAAAGGACGTCGCGAATGAATTTACACGAATACCAAGCAAAACAACTATTTGAGCATTAT
GGATTACCCGTAAAAAATGG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNKLALYCRPGFEKEVAAEITDQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIPFNRLIFARQMMVISDLLEDL
DPADRISPIVVAFEELSQQVNFAQSSELFVETADTNEAKELSTFCRKFTVPLRQALKKQGWLSAKASQKCGQFLHCFFVK
PNCCYVGYSYVDNHSSHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWLLNGWCRETIFNLKLPMKKRY
QEVILCLENLAVMLAEQNLNFDIQAKHLYHDREEITVHIALKP

Sequences:

>Translated_363_residues
MNKLALYCRPGFEKEVAAEITDQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIPFNRLIFARQMMVISDLLEDL
DPADRISPIVVAFEELSQQVNFAQSSELFVETADTNEAKELSTFCRKFTVPLRQALKKQGWLSAKASQKCGQFLHCFFVK
PNCCYVGYSYVDNHSSHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWLLNGWCRETIFNLKLPMKKRY
QEVILCLENLAVMLAEQNLNFDIQAKHLYHDREEITVHIALKP
>Mature_363_residues
MNKLALYCRPGFEKEVAAEITDQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIPFNRLIFARQMMVISDLLEDL
DPADRISPIVVAFEELSQQVNFAQSSELFVETADTNEAKELSTFCRKFTVPLRQALKKQGWLSAKASQKCGQFLHCFFVK
PNCCYVGYSYVDNHSSHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWLLNGWCRETIFNLKLPMKKRY
QEVILCLENLAVMLAEQNLNFDIQAKHLYHDREEITVHIALKP

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=359, Percent_Identity=59.6100278551532, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 41563; Mature: 41563

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLALYCRPGFEKEVAAEITDQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIP
CCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHCC
FNRLIFARQMMVISDLLEDLDPADRISPIVVAFEELSQQVNFAQSSELFVETADTNEAKE
HHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
LSTFCRKFTVPLRQALKKQGWLSAKASQKCGQFLHCFFVKPNCCYVGYSYVDNHSSHFMG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCEEEEECHHHCCCCCCEEC
IPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGL
CCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEECCCCCCCHHHHHHCCE
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWL
EEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHH
LNGWCRETIFNLKLPMKKRYQEVILCLENLAVMLAEQNLNFDIQAKHLYHDREEITVHIA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEEEEEE
LKP
ECC
>Mature Secondary Structure
MNKLALYCRPGFEKEVAAEITDQASHLGVFGFARVQDNSGYVIFECYQPDEADRLARDIP
CCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHCC
FNRLIFARQMMVISDLLEDLDPADRISPIVVAFEELSQQVNFAQSSELFVETADTNEAKE
HHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
LSTFCRKFTVPLRQALKKQGWLSAKASQKCGQFLHCFFVKPNCCYVGYSYVDNHSSHFMG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCEEEEECHHHCCCCCCEEC
IPRLKFPADAPSRSTLKLEEAILTFIPRKEENKRLNENMIGVDLGACPGGWTYQLVKRGL
CCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCEEEEEECCCCCCCHHHHHHCCE
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRKKVDWLVCDMVEQPSRISLLIGKWL
EEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHH
LNGWCRETIFNLKLPMKKRYQEVILCLENLAVMLAEQNLNFDIQAKHLYHDREEITVHIA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEEEEEEEE
LKP
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA