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The map label for this gene is recG

Identifier: 16273626

GI number: 16273626

Start: 1824562

End: 1826643

Strand: Reverse

Name: recG

Synonym: HI1740

Alternate gene names: 16273626

Gene position: 1826643-1824562 (Counterclockwise)

Preceding gene: 30995477

Following gene: 16273625

Centisome position: 99.81

GC content: 41.79

Gene sequence:

>2082_bases
ATGAGCCTTGAACTTCTCGATGCCGTGCCTTTGACCAGCCTTTCTGGTGTGGGGGCTGCCATTTCTAATAAACTGGCTAA
AATCGGCATTCATAATCTGCAAGATTTACTCTTTCATTTACCTATTCGCTATGAAGATCGTACGCGAATTACGCTAATCG
CTAATCTCCGCCCCGAACAATATTTTACCATTGAAGGAATTGTACAAACCTGTGAAGTCGCTTTTGGCCGTCGCCCGATT
TTATCGGTAAGTTTGTCAGACGGCACATCGAAAATTATGTTACGTTTTTTCAATTTTAATGCGGGAATGCGTAATAGTTT
TCAAGTTGGCGTGCGAGTAAAGGCTTTTGGCGAAGTGAAACGTGGGCGTCACATGCCAGAAATTCATCATCCAGAATATC
AAATTGTGCGAGATAATGCGCCCATAGTATTGGAAGAAACCCTAACGCCGATTTATTCCACAACGGAAGGGCTAAAACAA
AATTCATTACGAAAATTAACGGATCAGGCTTTGGCATTACTCGACAAAGTTCAGATTGCAGAAATTTTGCCTAATGAATT
TAATCCACATCAATATAGCTTAAAAGAGGCATTGCGATTATTGCATCGTCCGCCGCCAGATATTTCATTAGAAATGTTAG
AGCAAGGTAAGCATCCTGCACAACAACGATTAATTTTTGAAGAGCTTCTGGCACATAATTTAGCTATGCAAAAAGTGCGG
TTAGGAACGCAACAATTTTCTGCCTTACCGCTACATTATCAAACAGATTTGAAACAGCGATTTTTAGCCACCTTGCCATT
TCAACCCACTAATGCGCAAAAGCGAGTAGTGTCCGATATTGAACAAGATCTTATCAAAGATTATCCGATGATGCGCTTAG
TGCAAGGCGATGTGGGCTCGGGAAAAACATTGGTTGCCGCATTGGCTGCTTTAACTGCAATTGATAATGGCAAACAAGTC
GCCTTAATGGCGCCAACAGAAATTCTTGCAGAACAGCATGCGAATAATTTTAGACGGTGGTTTAAGCCTTTCGGTATTGA
AGTTGGCTGGTTGGCAGGTAAAGTAAAAGGAAAATCAAGACAAGCAGAGCTTGAAAAAATCAAAACTGGCGCGGTGCAAA
TGGTGGTGGGGACGCATGCTTTATTCCAAGAAGAAGTCGAGTTTTCCGACTTAGCATTAGTGATTATTGATGAACAACAT
CGTTTTGGGGTGCATCAACGATTAATGTTGCGTGAAAAAGGCGAAAAAGCGGGATTTTATCCCCATCAGTTAATTATGAC
GGCCACGCCGATTCCGAGAACGTTGGCAATGACCGTATATGCAGATTTGGATACATCAATTATTGATGAATTGCCTCCAG
GTCGTACGCCGATAACAACCGTAGTGGTTTCTGAAGAACGTCGAGCTGAAATTGTGATGCGTGTAAAAAACGCTTGTGTT
AATGAAAAACGTCAAGCCTATTGGGTGTGTACGTTAATTGATGAATCAGAGGTGTTAGAAGCTCAAGCAGCTGAAGCGAT
TTGGGAAGATTTAACGAAAGCGTTACCGATGTTAAATATTGGTTTAGTGCACGGGCGCATGAAACCCCAAGAAAAACAAG
ATGTCATGATGCGTTTTAAAAATGCAGAATTGGATTTATTGGTGGCAACGACAGTCATCGAAGTGGGTGTTGATGTTCCG
AATGCGAGTTTGATGATTATCGAAAATGCAGAACGTTTAGGTTTATCGCAGCTTCATCAGTTACGAGGGCGCGTCGGTCG
AGGCTGCACGGCTTCTTTTTGTGTACTAATGTATAAACCTCCGCTAGGTAAAGTTTCACAAAAACGCTTGCAGGTGCTAC
GAGATAGCCAAGATGGGTTTGTTATTTCGGAAAAAGATTTAGAAATTCGTGGGCCAGGTGAAGTACTTGGAACGAAACAA
ACGGGAATTGCTGAATTGCGAGTAGCAAATTTAATGCGAGATAGAAAAATGATACCAACGGTGCAACATTATGCGAAATC
ACTTATCCAAAAATACCCTGATGTGGCAGAAAGCCTAATCCGTCGCTGGCTCAATAATAAAGAAATTTACTCGAACGCTT
AA

Upstream 100 bases:

>100_bases
TGCAGGTTTGTGTAAAAGATATCAAACACCTTGCCAATATCGTTCATCGTATTAAAGGCATCACTGGCGTCGTTAATGTC
AAACGCAATATTAATGAGCT

Downstream 100 bases:

>100_bases
AAGTGCGGTCAATTTTCAAAGAGTTTTAAATGGATAAAAAAGAAAAACGCCCAACAGTGCTCTTTTTTGATTCTGGAGTG
GGTGGGTTTAGCGTATATCG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQYFTIEGIVQTCEVAFGRRPI
LSVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVKRGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQ
NSLRKLTDQALALLDKVQIAEILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVR
LGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGSGKTLVAALAALTAIDNGKQV
ALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQH
RFGVHQRLMLREKGEKAGFYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACV
NEKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFKNAELDLLVATTVIEVGVDVP
NASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKPPLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQ
TGIAELRVANLMRDRKMIPTVQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA

Sequences:

>Translated_693_residues
MSLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQYFTIEGIVQTCEVAFGRRPI
LSVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVKRGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQ
NSLRKLTDQALALLDKVQIAEILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVR
LGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGSGKTLVAALAALTAIDNGKQV
ALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQH
RFGVHQRLMLREKGEKAGFYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACV
NEKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFKNAELDLLVATTVIEVGVDVP
NASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKPPLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQ
TGIAELRVANLMRDRKMIPTVQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA
>Mature_692_residues
SLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQYFTIEGIVQTCEVAFGRRPIL
SVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVKRGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQN
SLRKLTDQALALLDKVQIAEILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVRL
GTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGSGKTLVAALAALTAIDNGKQVA
LMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSRQAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQHR
FGVHQRLMLREKGEKAGFYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACVN
EKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFKNAELDLLVATTVIEVGVDVPN
ASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKPPLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQT
GIAELRVANLMRDRKMIPTVQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=66.9552669552669, Blast_Score=939, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=392, Percent_Identity=38.5204081632653, Blast_Score=250, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECG_HAEIN (P43809)

Other databases:

- EMBL:   L42023
- PIR:   E64139
- RefSeq:   NP_439884.1
- ProteinModelPortal:   P43809
- SMR:   P43809
- GeneID:   950549
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1740
- NMPDR:   fig|71421.1.peg.1654
- TIGR:   HI_1740
- HOGENOM:   HBG747311
- OMA:   VLGTKQT
- ProtClustDB:   PRK10917
- BioCyc:   HINF71421:HI_1740-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365
- SMART:   SM00487
- SMART:   SM00490
- TIGRFAMs:   TIGR00643

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =3.6.4.12

Molecular weight: Translated: 78087; Mature: 77956

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCC
YFTIEGIVQTCEVAFGRRPILSVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVK
EEEHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEEEEHHHHH
RGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQNSLRKLTDQALALLDKVQIA
CCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVR
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGS
HCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALTAIDNGKQVALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
QAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQHRFGVHQRLMLREKGEKAGFY
HHHHHHHHHCCEEEEHHHHHHHHHHCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACV
CCEEEEECCCCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
NEKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFK
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHEEHEEECCCCCCHHHHHHHHHC
NAELDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKP
CCCEEEEHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCCEEEEEEECC
PLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQTGIAELRVANLMRDRKMIPT
CCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
VQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA
HHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLELLDAVPLTSLSGVGAAISNKLAKIGIHNLQDLLFHLPIRYEDRTRITLIANLRPEQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCC
YFTIEGIVQTCEVAFGRRPILSVSLSDGTSKIMLRFFNFNAGMRNSFQVGVRVKAFGEVK
EEEHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEEEEHHHHH
RGRHMPEIHHPEYQIVRDNAPIVLEETLTPIYSTTEGLKQNSLRKLTDQALALLDKVQIA
CCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILPNEFNPHQYSLKEALRLLHRPPPDISLEMLEQGKHPAQQRLIFEELLAHNLAMQKVR
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LGTQQFSALPLHYQTDLKQRFLATLPFQPTNAQKRVVSDIEQDLIKDYPMMRLVQGDVGS
HCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALTAIDNGKQVALMAPTEILAEQHANNFRRWFKPFGIEVGWLAGKVKGKSR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
QAELEKIKTGAVQMVVGTHALFQEEVEFSDLALVIIDEQHRFGVHQRLMLREKGEKAGFY
HHHHHHHHHCCEEEEHHHHHHHHHHCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVVVSEERRAEIVMRVKNACV
CCEEEEECCCCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
NEKRQAYWVCTLIDESEVLEAQAAEAIWEDLTKALPMLNIGLVHGRMKPQEKQDVMMRFK
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHEEHEEECCCCCCHHHHHHHHHC
NAELDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGCTASFCVLMYKP
CCCEEEEHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCCEEEEEEECC
PLGKVSQKRLQVLRDSQDGFVISEKDLEIRGPGEVLGTKQTGIAELRVANLMRDRKMIPT
CCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
VQHYAKSLIQKYPDVAESLIRRWLNNKEIYSNA
HHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800