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The map label for this gene is erpA [H]

Identifier: 16273609

GI number: 16273609

Start: 1795468

End: 1795812

Strand: Direct

Name: erpA [H]

Synonym: HI1723

Alternate gene names: 16273609

Gene position: 1795468-1795812 (Clockwise)

Preceding gene: 30995473

Following gene: 30995474

Centisome position: 98.11

GC content: 39.42

Gene sequence:

>345_bases
ATGATAGATGATATGGCGGTGCCACTGACATTTACTGATGCAGCGGCAAATAAAGTAAAAAGTTTAATCAGCGAAGAAGA
AAATACTGATTTGAAATTACGCGTGTATATCACAGGGGGTGGTTGCAGCGGTTTCCAATATGGTTTTACCTTTGATGAAA
AAGTCAATGACGGCGATTTAACCATTGAAAAATCAGGGGTTCAACTTGTGATTGACCCGATGAGCTTACAATATTTAATC
GGCGGTACAGTCGATTACACAGAAGGTTTAGAGGGTTCACGTTTTACTGTAAATAATCCAAATGCTACCAGCACTTGTGG
CTGTGGTTCATCCTTTAGTATCTAA

Upstream 100 bases:

>100_bases
TATAGCACGATTTCTAGGAAAAAACTGGATTGCACTTGAATGGAGTAAAGGGTTATTAGATAATGGCGGGATTGAAATTT
TAGGAAAGTAGGAAATAGTT

Downstream 100 bases:

>100_bases
GATGGATTTTCAATTTACACATTATCAAGGCAATGTATCCGTCAAATGTTCGATGGAACACATTGCCCTTGCTAACTGGT
TCAACACAGAAGTGCGGTCA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTDLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI

Sequences:

>Translated_114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTDLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
>Mature_114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTDLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=97, Percent_Identity=44.3298969072165, Blast_Score=84, Evalue=2e-17,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=34.9056603773585, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=81.5789473684211, Blast_Score=198, Evalue=9e-53,
Organism=Escherichia coli, GI1788877, Length=108, Percent_Identity=37.962962962963, Blast_Score=70, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=42.5925925925926, Blast_Score=88, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=29.2035398230088, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=30.5555555555556, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=32.0754716981132, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=49.3975903614458, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12194; Mature: 12194

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDMAVPLTFTDAAANKVKSLISEEENTDLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKSGVQLVIDPMSLQYLIGGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDDMAVPLTFTDAAANKVKSLISEEENTDLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKSGVQLVIDPMSLQYLIGGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA