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The map label for this gene is insK [C]

Identifier: 30995473

GI number: 30995473

Start: 1793696

End: 1794463

Strand: Direct

Name: insK [C]

Synonym: HI1721

Alternate gene names: 30995473

Gene position: 1793696-1794463 (Clockwise)

Preceding gene: 30995472

Following gene: 16273609

Centisome position: 98.01

GC content: 38.54

Gene sequence:

>768_bases
TTGGCACGCAGTGTTTTCTTCTATCACTTGAAGACGAAAAACGATAAAAATGCAGCACTCTCACAAGAAATCGCCTCTAT
TTATCACGATAATCACGGAAACTATGGTTATCGCCGTGTGACGTTTAAGCTAAGAGAAACCATTAAAATTAACCATAAAA
AAGTGCAACGTATTATGCAATGGTTGGGGCTTAAGGGAAAATGCAAGACACAAAAATATCGTTCTTATCAAGGTGAAGTC
GGGCATATTGCGGATAATCTGTTACAACGCGATTTTACGGCAACACAGCCTAATGAAAAATGGACAACCGATATTACCGA
GTTCAAGTGTGCGGAAGGCAAGCTCTATTTATCCCCAATTAAGGATTTATTTAACAATGAAATTATTGCTTATGATTTAG
CGCGAAGCCCGAACTTTGAGCAAATTACCAGAATGATGAAACAAGCTGTAGCAAGGCTTGAAGGCGCAAAACCGATTTTA
CATTCCGACCAAGGTTGGCAGTATCAGATGATAGGTTATCAAAACATACTCAGGGAGAATGGCATTCAACAAAGTATGTC
AAGGAAGGGGAATTGTTTATATAACAGTGCGATGGAAAGCTTCTTTGGGAGATTAAAAACGGAATGTTATTACGGCAAAC
GATTTGAAACGTTCGAACAACTGGAAAAAACGATTCATGAATATATTCATTATTACAACCATGAACGCATTCAGGGGAAA
CTAAAAGGACTCAGCCCTGTGAATTACAGAACTCAGTCCTTGAACTAA

Upstream 100 bases:

>100_bases
AGTTGCAAGAGCTCAACCAACAAAAAATGCAGAAAAAGCCGCTATCGTAAAGGCATTACGCGTTCATTTTCCGCTGCCCA
TTTTATTAGATTTAATCGGC

Downstream 100 bases:

>100_bases
ATCAGTCTAACTTTTTGGGGTCAGATCAATATCTACGCCCTTATCTTATAATTTTATGCCAATTACACATTCACCATAAT
CCGCGAAATTCGACCTTCTG

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MARSVFFYHLKTKNDKNAALSQEIASIYHDNHGNYGYRRVTFKLRETIKINHKKVQRIMQWLGLKGKCKTQKYRSYQGEV
GHIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPIKDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPIL
HSDQGWQYQMIGYQNILRENGIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGK
LKGLSPVNYRTQSLN

Sequences:

>Translated_255_residues
MARSVFFYHLKTKNDKNAALSQEIASIYHDNHGNYGYRRVTFKLRETIKINHKKVQRIMQWLGLKGKCKTQKYRSYQGEV
GHIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPIKDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPIL
HSDQGWQYQMIGYQNILRENGIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGK
LKGLSPVNYRTQSLN
>Mature_254_residues
ARSVFFYHLKTKNDKNAALSQEIASIYHDNHGNYGYRRVTFKLRETIKINHKKVQRIMQWLGLKGKCKTQKYRSYQGEVG
HIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPIKDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPILH
SDQGWQYQMIGYQNILRENGIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGKL
KGLSPVNYRTQSLN

Specific function: Involved in the transposition of the insertion sequence is150 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=195, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=7e-18,
Organism=Escherichia coli, GI1789981, Length=257, Percent_Identity=56.0311284046693, Blast_Score=299, Evalue=1e-82,
Organism=Escherichia coli, GI1788405, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787263, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786753, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786570, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786490, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30109; Mature: 29978

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSVFFYHLKTKNDKNAALSQEIASIYHDNHGNYGYRRVTFKLRETIKINHKKVQRIMQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHH
WLGLKGKCKTQKYRSYQGEVGHIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPI
HHCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCEEHHHH
KDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPILHSDQGWQYQMIGYQNILREN
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHC
GIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
LKGLSPVNYRTQSLN
HCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARSVFFYHLKTKNDKNAALSQEIASIYHDNHGNYGYRRVTFKLRETIKINHKKVQRIMQ
CCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHH
WLGLKGKCKTQKYRSYQGEVGHIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPI
HHCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCEEHHHH
KDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPILHSDQGWQYQMIGYQNILREN
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHC
GIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
LKGLSPVNYRTQSLN
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]