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The map label for this gene is crr

Identifier: 16273598

GI number: 16273598

Start: 1783345

End: 1783845

Strand: Reverse

Name: crr

Synonym: HI1711

Alternate gene names: 16273598

Gene position: 1783845-1783345 (Counterclockwise)

Preceding gene: 16273599

Following gene: 16273597

Centisome position: 97.47

GC content: 36.93

Gene sequence:

>501_bases
ATGGGCTTATTTGACAAGTTATTTGGTTCAAAAGAAAACAAATCTGTGGAAGTTGAAATTTATGCACGCATCTCTGGCGA
GATCGTTAATATTGAAGATGTTCCCGATGTGGTTTTCTCTGAAAAAATTGTTGGTGATGGTGTTGCTGTTCGTCCTATTG
GTAACAAAATCGTTGCGCCAGTGGATGGTGTGATTGGTAAAATTTTTGAAACCAATCACGCTTTTTCAATGGAATCAAAA
GAAGGCGTAGAATTATTTGTACACTTTGGTATTGATACTGTTGAGTTAAAGGGGGAAGGCTTTACTCGTATTGCACAAGA
AGGGCAATCTGTTAAGCGTGGCGATACTGTGATTGAATTTGATCTTGCGCTATTAGAATCAAAAGCAAAATCTGTCTTAA
CACCAATCGTAATTTCAAATATGGACGAAATTTCTTGTATCGTAAAAAAATCAGGCGAAGTAGTGGCTGGAGAATCAGTG
GTATTAGCCTTAAAGAAATAA

Upstream 100 bases:

>100_bases
AATTAATTGAAGAATTTTTGCTGGAAAATTCATTAAATTAAACAAAATTATTTGATTTTACGTTAAAATAGCAACCATCT
TGAATGGATAGGAGATTAAA

Downstream 100 bases:

>100_bases
TTTGTTTACGGTAAAAAAAGTCCGCCTTTGTGCGGATTTTTTATTTATTATAGTTACCTAGGGTAAGTATACCCTAGGCT
AATTTAAGTGCTACCCCGTT

Product: PTS system glucose-specific transporter subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MGLFDKLFGSKENKSVEVEIYARISGEIVNIEDVPDVVFSEKIVGDGVAVRPIGNKIVAPVDGVIGKIFETNHAFSMESK
EGVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTVIEFDLALLESKAKSVLTPIVISNMDEISCIVKKSGEVVAGESV
VLALKK

Sequences:

>Translated_166_residues
MGLFDKLFGSKENKSVEVEIYARISGEIVNIEDVPDVVFSEKIVGDGVAVRPIGNKIVAPVDGVIGKIFETNHAFSMESK
EGVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTVIEFDLALLESKAKSVLTPIVISNMDEISCIVKKSGEVVAGESV
VLALKK
>Mature_165_residues
GLFDKLFGSKENKSVEVEIYARISGEIVNIEDVPDVVFSEKIVGDGVAVRPIGNKIVAPVDGVIGKIFETNHAFSMESKE
GVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTVIEFDLALLESKAKSVLTPIVISNMDEISCIVKKSGEVVAGESVV
LALKK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain

Homologues:

Organism=Escherichia coli, GI1788757, Length=169, Percent_Identity=72.7810650887574, Blast_Score=234, Evalue=2e-63,
Organism=Escherichia coli, GI1786894, Length=149, Percent_Identity=45.6375838926174, Blast_Score=142, Evalue=8e-36,
Organism=Escherichia coli, GI1790159, Length=161, Percent_Identity=33.5403726708075, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): PTGA_HAEIN (P45338)

Other databases:

- EMBL:   L42023
- PIR:   G64137
- RefSeq:   NP_439853.1
- ProteinModelPortal:   P45338
- SMR:   P45338
- GeneID:   950531
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1711
- NMPDR:   fig|71421.1.peg.1624
- TIGR:   HI_1711
- HOGENOM:   HBG517865
- OMA:   DEISCIV
- ProtClustDB:   PRK09439
- BioCyc:   HINF71421:HI_1711-MONOMER
- GO:   GO:0005737
- GO:   GO:0016020
- InterPro:   IPR011055
- InterPro:   IPR001127
- TIGRFAMs:   TIGR00830

Pfam domain/function: PF00358 PTS_EIIA_1; SSF51261 Dup_hybrid_motif

EC number: 2.7.1.69

Molecular weight: Translated: 17911; Mature: 17780

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS51093 PTS_EIIA_TYPE_1; PS00371 PTS_EIIA_TYPE_1_HIS

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFDKLFGSKENKSVEVEIYARISGEIVNIEDVPDVVFSEKIVGDGVAVRPIGNKIVAP
CCCHHHHHCCCCCCEEEEEEEEEECCCEEEECCCCCHHHHHHCCCCCEEEEECCCEEECC
VDGVIGKIFETNHAFSMESKEGVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTVIEF
HHHHHHHHHCCCCEECCCCCCCEEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCEEEEE
DLALLESKAKSVLTPIVISNMDEISCIVKKSGEVVAGESVVLALKK
HHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEEECCEEEEEEEC
>Mature Secondary Structure 
GLFDKLFGSKENKSVEVEIYARISGEIVNIEDVPDVVFSEKIVGDGVAVRPIGNKIVAP
CCHHHHHCCCCCCEEEEEEEEEECCCEEEECCCCCHHHHHHCCCCCEEEEECCCEEECC
VDGVIGKIFETNHAFSMESKEGVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTVIEF
HHHHHHHHHCCCCEECCCCCCCEEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCEEEEE
DLALLESKAKSVLTPIVISNMDEISCIVKKSGEVVAGESVVLALKK
HHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023