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The map label for this gene is sohB

Identifier: 16273569

GI number: 16273569

Start: 1751640

End: 1752701

Strand: Direct

Name: sohB

Synonym: HI1682

Alternate gene names: 16273569

Gene position: 1751640-1752701 (Clockwise)

Preceding gene: 16273566

Following gene: 16273570

Centisome position: 95.71

GC content: 33.52

Gene sequence:

>1062_bases
ATGTTGAACGATATTTTAACAGGCTATGGAATTTTTATTTTGGAAATTTTAACAATTTTATTACTCATTCTTGCTGTTGT
TGGTTTGATTATTTCTTATCGCCAACATAACAAGTCTAAAGTGGGAGAATTAGAAATTAAAGATTTATCAGAAGAATTTA
ATGAACAAGTTCGTTTATTACGTGATTTTAATCTTTCTGAAGAAGAACAAAAACAACGCACTAAAGCTGAAAAAAAAGCG
GAAAAACAAAATGCTAAAAAACGCAAAGAAAAATTGAAAAAAGGCGAGACTTTAGAAGATGAAAAGAAAGCTTGCGTATA
TGTATTAGATTTTTGCGGCGATATTTCAGCCTCAGAAACAACCGCACTTCGAGAAGAAATTTCAGCTATCTTAAATGTCG
CCAAATCTGAAGATGAAGTATTACTACGTTTAGAAAGTCCTGGTGGCATTGTGCATAATTATGGATTTGCAGCCTCTCAA
TTGTCTCGCTTAAAACAAAAAGGCATAAAATTAACTGTTGCCGTTGATAAAGTGGCTGCAAGTGGCGGTTATATGATGGC
TTGCGTTGCCGATAAAATTGTATCCGCACCTTTTGCTGTTATTGGTTCTATTGGCGTTGTCGCTCAAATTCCAAATGTTC
ATCGACTATTGAAAAAACACGATGTCGATGTAGATGTAATGACTGCGGGCGAATTTAAACGTACAGTGACCGTATTGGGT
GAGAACACTGAAAAAGGAAAACAAAAATTTCAACAAGAATTGGAAGAAACACATAAATTATTCAAACAATTTGTCTCACA
AAATCGCCCTTGCCTAGATATTGATAAAATTGCAACAGGCGAACATTGGTTTGGACAACAAGCCATTGCATTACAACTTG
TAGATGAAATCTCAACGAGTGATGATTTAATTTTGGAAAAAATGAAAGAAAAACAGGTACTTAATGTTAAATACCGTTTA
AAAAAATCCCTAATAAAAAAATTCGGACGACAAGCTGAAGAAAGTGCAATTAATATCATTCATCGTTATAGTACAAAACA
GTCTAGAGACTTTATGTACTAA

Upstream 100 bases:

>100_bases
TAAATAGCACAAACAATCACAATGTTTTATTATGTTGGCGATCTACACACTAAACCAGTGTCGTGAAAATTTAATCCATT
AAATATCAACGGGAGTAACA

Downstream 100 bases:

>100_bases
ACATTTACCCACAAAAAAGAAGTTTTTATTTCTATGTTTACAAGACAAATCTTTGTCATTAAGATACTCGCCGATCTTTA
GGGGTTTTATTATATTTAAT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLLRDFNLSEEEQKQRTKAEKKA
EKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASETTALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQ
LSRLKQKGIKLTVAVDKVAASGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLG
ENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTSDDLILEKMKEKQVLNVKYRL
KKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY

Sequences:

>Translated_353_residues
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLLRDFNLSEEEQKQRTKAEKKA
EKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASETTALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQ
LSRLKQKGIKLTVAVDKVAASGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLG
ENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTSDDLILEKMKEKQVLNVKYRL
KKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY
>Mature_353_residues
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLLRDFNLSEEEQKQRTKAEKKA
EKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASETTALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQ
LSRLKQKGIKLTVAVDKVAASGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLG
ENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTSDDLILEKMKEKQVLNVKYRL
KKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY

Specific function: Possible protease

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=53.5816618911175, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI1788064, Length=167, Percent_Identity=31.1377245508982, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOHB_HAEIN (P45315)

Other databases:

- EMBL:   L42023
- PIR:   D64136
- RefSeq:   NP_439824.1
- ProteinModelPortal:   P45315
- SMR:   P45315
- MEROPS:   S49.002
- GeneID:   950509
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1682
- NMPDR:   fig|71421.1.peg.1595
- TIGR:   HI_1682
- HOGENOM:   HBG366205
- OMA:   LEETHVL
- ProtClustDB:   PRK11778
- BioCyc:   HINF71421:HI_1682-MONOMER
- GO:   GO:0006508
- InterPro:   IPR002142
- InterPro:   IPR013703

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N

EC number: 3.4.21.-

Molecular weight: Translated: 39873; Mature: 39873

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: ACT_SITE 181-181

Signals:

None

Transmembrane regions:

HASH(0xdc01298)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RDFNLSEEEQKQRTKAEKKAEKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHH
TALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQLSRLKQKGIKLTVAVDKVAA
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHCCCEEEEEEEHHHC
SGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLG
CCCEEHHHHHHHHHHCHHHHHHCHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHEEEEEC
ENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHCCHHHHHHHHHHHCCC
DDLILEKMKEKQVLNVKYRLKKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RDFNLSEEEQKQRTKAEKKAEKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHH
TALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQLSRLKQKGIKLTVAVDKVAA
HHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHCCCEEEEEEEHHHC
SGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLG
CCCEEHHHHHHHHHHCHHHHHHCHHHHHCCCHHHHHHHHCCCCEEEEECCCHHHEEEEEC
ENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHCCHHHHHHHHHHHCCC
DDLILEKMKEKQVLNVKYRLKKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800