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The map label for this gene is 16273480

Identifier: 16273480

GI number: 16273480

Start: 1653802

End: 1655361

Strand: Reverse

Name: 16273480

Synonym: HI1586

Alternate gene names: NA

Gene position: 1655361-1653802 (Counterclockwise)

Preceding gene: 16273484

Following gene: 16273479

Centisome position: 90.45

GC content: 38.08

Gene sequence:

>1560_bases
ATGCTTTCCGTTCTCTCCATTAATTATAGGTATTATTTAATGGAACTTATTGATTTTTCATCATCTGTTTGGTCAATCGT
CCCTGCTTTGTTGGCGATAATTTTGGCGATAGCAACTCGCCGTGTTTTGGTTTCCCTTAGTGCGGGGATTATTATTGGAT
CATTAATGTTAAGCGATTGGCAAATCGGCAGCGCATTTAATTATTTGGTAAAAAATGTGGTTTCTTTGGTTTATGCCGAT
GGTGAAATCAATTCAAATATGAACATTGTTTTGTTCTTATTATTGCTTGGTGTTTTAACCGCACTTTTAACCGTATCAGG
TAGTAATCGTGCCTTTGCTGAATGGGCACAAAGCCGTATTAAAGGTCGTCGTGGTGCTAAATTATTAGCGGCATCATTGG
TTTTTGTTACTTTTATTGACGATTATTTCCATAGTCTCGCTGTAGGCGCAATTGCTCGTCCTGTGACAGATCGTTTTAAA
GTTTCTCGTGCGAAACTTGCTTATATTTTAGATTCAACGGCAGCACCGATGTGTGTAATGATGCCAGTTTCCAGTTGGGG
CGCATATATTATTACTTTAATAGGCGGTTTATTAGCGACTTATTCGATCACGGAGTACACACCAATTGGTGCATTCGTAG
CAATGAGTTCAATGAACTTCTATGCAATTTTCTCCATTATTATGGTGTTTTTTGTGGCATATTTTTCTTTTGATATTGCT
TCAATGGTGCGTCACGAAAAATTAGCTTTGAAAAATACTGAAGATCAGTTGGAAGAAGAAACGGGTACAAAAGGTCAGGT
GCGTAATCTTATATTACCTATTTTAGTTTTAATTATCGCTACAGTTTCAATGATGATTTACACAGGCGCAGAGGCATTGG
CTGCGGATGGCAAAGTGTTTAGTGTTTTAGGTACATTTGAAAACACCGTAGTAGGAACATCTTTGGTTGTAGGTGGATTC
TGTTCAATTATTATTTCTACTTTATTAATTATTCTTGATCGTCAAGTGAGTGTTCCTGAATATGTACGTTCTTGGATTGT
GGGAATTAAATCAATGTCAGGTGCAATCGCAATTTTATTCTTTGCTTGGACAATTAATAAAATAGTAGGTGATATGCAAA
CAGGTAAATATCTATCTTCTCTTGTGTCTGGTAATATTCCAATGCAATTTTTGCCTGTTATACTTTTTGTTCTTGGTGCA
GCGATGGCATTTTCAACAGGTACGAGCTGGGGAACATTCGGTATTATGTTACCAATTGCCGCAGCAATGGCAGCGAATGC
CGCACCAGAATTATTGCTTCCTTGTTTATCTGCAGTAATGGCAGGGGCTGTATGTGGCGATCATTGTTCGCCAGTGTCGG
ATACAACAATTTTGTCTTCAACGGGCGCAAAATGTAATCATATTGATCACGTTACTACTCAGCTTCCTTATGCTGCCACA
GTTGCAACAGCGACTTCTATTGGTTACATTGTGGTAGGGTTTACTTATTCAGGTTTAGCTGGTTTTGCAGCAACGGCAGT
TTCATTGATTGTCATTATATTTGCAGTTAAAAAACGCTAA

Upstream 100 bases:

>100_bases
CGTTTTGTTTGGTTGGTGGCGTGCTCGAAAGGGGCGACACTGTCATAGTTTTTCTGATTAACTATGGAGTGCTACGGTTG
TTCTGGTCTTATTCTGTCCT

Downstream 100 bases:

>100_bases
AACTGTGATCTCATTCAAAAATTTGAATAAAAAATAATATTTTTACTATTTTATAAAATGCGGCATTTTGTCGCATTTTT
TTATTTTTATTGATGGAAAA

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MLSVLSINYRYYLMELIDFSSSVWSIVPALLAIILAIATRRVLVSLSAGIIIGSLMLSDWQIGSAFNYLVKNVVSLVYAD
GEINSNMNIVLFLLLLGVLTALLTVSGSNRAFAEWAQSRIKGRRGAKLLAASLVFVTFIDDYFHSLAVGAIARPVTDRFK
VSRAKLAYILDSTAAPMCVMMPVSSWGAYIITLIGGLLATYSITEYTPIGAFVAMSSMNFYAIFSIIMVFFVAYFSFDIA
SMVRHEKLALKNTEDQLEEETGTKGQVRNLILPILVLIIATVSMMIYTGAEALAADGKVFSVLGTFENTVVGTSLVVGGF
CSIIISTLLIILDRQVSVPEYVRSWIVGIKSMSGAIAILFFAWTINKIVGDMQTGKYLSSLVSGNIPMQFLPVILFVLGA
AMAFSTGTSWGTFGIMLPIAAAMAANAAPELLLPCLSAVMAGAVCGDHCSPVSDTTILSSTGAKCNHIDHVTTQLPYAAT
VATATSIGYIVVGFTYSGLAGFAATAVSLIVIIFAVKKR

Sequences:

>Translated_519_residues
MLSVLSINYRYYLMELIDFSSSVWSIVPALLAIILAIATRRVLVSLSAGIIIGSLMLSDWQIGSAFNYLVKNVVSLVYAD
GEINSNMNIVLFLLLLGVLTALLTVSGSNRAFAEWAQSRIKGRRGAKLLAASLVFVTFIDDYFHSLAVGAIARPVTDRFK
VSRAKLAYILDSTAAPMCVMMPVSSWGAYIITLIGGLLATYSITEYTPIGAFVAMSSMNFYAIFSIIMVFFVAYFSFDIA
SMVRHEKLALKNTEDQLEEETGTKGQVRNLILPILVLIIATVSMMIYTGAEALAADGKVFSVLGTFENTVVGTSLVVGGF
CSIIISTLLIILDRQVSVPEYVRSWIVGIKSMSGAIAILFFAWTINKIVGDMQTGKYLSSLVSGNIPMQFLPVILFVLGA
AMAFSTGTSWGTFGIMLPIAAAMAANAAPELLLPCLSAVMAGAVCGDHCSPVSDTTILSSTGAKCNHIDHVTTQLPYAAT
VATATSIGYIVVGFTYSGLAGFAATAVSLIVIIFAVKKR
>Mature_519_residues
MLSVLSINYRYYLMELIDFSSSVWSIVPALLAIILAIATRRVLVSLSAGIIIGSLMLSDWQIGSAFNYLVKNVVSLVYAD
GEINSNMNIVLFLLLLGVLTALLTVSGSNRAFAEWAQSRIKGRRGAKLLAASLVFVTFIDDYFHSLAVGAIARPVTDRFK
VSRAKLAYILDSTAAPMCVMMPVSSWGAYIITLIGGLLATYSITEYTPIGAFVAMSSMNFYAIFSIIMVFFVAYFSFDIA
SMVRHEKLALKNTEDQLEEETGTKGQVRNLILPILVLIIATVSMMIYTGAEALAADGKVFSVLGTFENTVVGTSLVVGGF
CSIIISTLLIILDRQVSVPEYVRSWIVGIKSMSGAIAILFFAWTINKIVGDMQTGKYLSSLVSGNIPMQFLPVILFVLGA
AMAFSTGTSWGTFGIMLPIAAAMAANAAPELLLPCLSAVMAGAVCGDHCSPVSDTTILSSTGAKCNHIDHVTTQLPYAAT
VATATSIGYIVVGFTYSGLAGFAATAVSLIVIIFAVKKR

Specific function: Unknown

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1586_HAEIN (P44263)

Other databases:

- EMBL:   L42023
- PIR:   C64037
- RefSeq:   NP_439731.1
- GeneID:   950450
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1586
- NMPDR:   fig|71421.1.peg.1506
- TIGR:   HI_1586
- HOGENOM:   HBG741626
- OMA:   TRERLAY
- ProtClustDB:   CLSK870280
- BioCyc:   HINF71421:HI_1586-MONOMER
- InterPro:   IPR018461

Pfam domain/function: PF03553 Na_H_antiporter

EC number: NA

Molecular weight: Translated: 55499; Mature: 55499

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeca39d0)-; HASH(0xecc667c)-; HASH(0xedb9e9c)-; HASH(0xea6bde0)-; HASH(0xe45f304)-; HASH(0xe986924)-; HASH(0xe936690)-; HASH(0xe8477a8)-; HASH(0xcf1df6c)-; HASH(0xdc04174)-; HASH(0xdb1ab84)-; HASH(0xe88c630)-; HASH(0xedc5c48)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVLSINYRYYLMELIDFSSSVWSIVPALLAIILAIATRRVLVSLSAGIIIGSLMLSDW
CCEEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QIGSAFNYLVKNVVSLVYADGEINSNMNIVLFLLLLGVLTALLTVSGSNRAFAEWAQSRI
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KGRRGAKLLAASLVFVTFIDDYFHSLAVGAIARPVTDRFKVSRAKLAYILDSTAAPMCVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MPVSSWGAYIITLIGGLLATYSITEYTPIGAFVAMSSMNFYAIFSIIMVFFVAYFSFDIA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SMVRHEKLALKNTEDQLEEETGTKGQVRNLILPILVLIIATVSMMIYTGAEALAADGKVF
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCE
SVLGTFENTVVGTSLVVGGFCSIIISTLLIILDRQVSVPEYVRSWIVGIKSMSGAIAILF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
FAWTINKIVGDMQTGKYLSSLVSGNIPMQFLPVILFVLGAAMAFSTGTSWGTFGIMLPIA
HHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAMAANAAPELLLPCLSAVMAGAVCGDHCSPVSDTTILSSTGAKCNHIDHVTTQLPYAAT
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCHHHH
VATATSIGYIVVGFTYSGLAGFAATAVSLIVIIFAVKKR
HHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLSVLSINYRYYLMELIDFSSSVWSIVPALLAIILAIATRRVLVSLSAGIIIGSLMLSDW
CCEEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QIGSAFNYLVKNVVSLVYADGEINSNMNIVLFLLLLGVLTALLTVSGSNRAFAEWAQSRI
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KGRRGAKLLAASLVFVTFIDDYFHSLAVGAIARPVTDRFKVSRAKLAYILDSTAAPMCVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MPVSSWGAYIITLIGGLLATYSITEYTPIGAFVAMSSMNFYAIFSIIMVFFVAYFSFDIA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SMVRHEKLALKNTEDQLEEETGTKGQVRNLILPILVLIIATVSMMIYTGAEALAADGKVF
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCE
SVLGTFENTVVGTSLVVGGFCSIIISTLLIILDRQVSVPEYVRSWIVGIKSMSGAIAILF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
FAWTINKIVGDMQTGKYLSSLVSGNIPMQFLPVILFVLGAAMAFSTGTSWGTFGIMLPIA
HHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAMAANAAPELLLPCLSAVMAGAVCGDHCSPVSDTTILSSTGAKCNHIDHVTTQLPYAAT
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCHHHH
VATATSIGYIVVGFTYSGLAGFAATAVSLIVIIFAVKKR
HHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800