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The map label for this gene is trpD [H]

Identifier: 16273299

GI number: 16273299

Start: 1485166

End: 1486167

Strand: Direct

Name: trpD [H]

Synonym: HI1389

Alternate gene names: 16273299

Gene position: 1485166-1486167 (Clockwise)

Preceding gene: 16273298

Following gene: 16273300

Centisome position: 81.15

GC content: 41.02

Gene sequence:

>1002_bases
ATGCAACACAACCAATTATTAGAACAACTTTATAGCGGACATTCACTTTCAACCTCAGAAAGCACCGCTCTTTTTAATGC
AGTCATCCAAGGTGAGCTTTCCAATGAACAAATTGCTGCAATGCTTATTGCTTTAAAAGTGCGGGGAGCAAATACTGAGG
AAATTTCGGGTGCCGTTGCCGCCTCATTACAAAATGCCAAAGCATTTCCATATCCAAATTATCCTTTTGCGGATATTGTA
GGAACAGGAGGCAATGGTCAAAACACTATTAATATTTCCACTACCAGTGCGATTGTTGCGGCATCAATGGGAGCAAAAAT
AGCAAAACATGGCAATCGTAGCGTGTCGAGTAAATCAGGTGCTAGCGATGTGCTTACCGCACTTAGCGTTAATGTGAACG
TCACACCAGAGCAAGCTCGACAAGCGTTAGATGAAATTGGTGTCTGTTTTTTATTTGCTCAACAATATCATTCTGGTTTC
CGTCATGTTGCGCCAGTCCGTGCCGCTTTAAAAACGCGCACTATCTTTAATATTTTAGGGCCGCTTATCAATCCTGCTCG
CCCAACTTATCATTTACTTGGCGTATATGCGCCTGAATTAGTAAAAACCTATGCTGAAACCGCAGTTGCCTTAGAACATC
AACATTCCTTTGTTGTACATGGTTCTGGCTTAGATGAAGTCGCATTGCACGGCGAAACACAAGTGGCAGAAATTAAAAAT
GGCAAAATTGAATATTTCACTTTAACGCCTGAAGATTTTGGCTTAAAAACGCAATCCCTCGAAAGTCTTCGCGGTGGTGA
ACCACAAGAAAATGCCCAATATCTGACCGCACTTTTACAAGGTAAAGGAAAAGCTGAACACGCTAATGCGGTGGCGGCAA
ACACGGCATTATTATTGAAATTATTCGGTTACGATGATTTAAAACAAAATGTGCAAAATGTACTGGCGCATCTTGTATCA
GGTAAAGCCTTTGAAACATTACAGAAATTAACCACATATTAA

Upstream 100 bases:

>100_bases
ATGACAGGTGATGAGGCGCGCGATTTAGATTACGATATTTATGTTTAATAAAATATAGAAAATTAACAAATCCATATACA
AAGAAAAACAGGAATAGACT

Downstream 100 bases:

>100_bases
TAAAAGCTAATTTTATACGCCACAATAAGAAGAAAAATGATGATCACTCAAGATTTTACCAAACCCATTGATTCCGCTAC
GGTGCTACAAAAAATCGTGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQHNQLLEQLYSGHSLSTSESTALFNAVIQGELSNEQIAAMLIALKVRGANTEEISGAVAASLQNAKAFPYPNYPFADIV
GTGGNGQNTINISTTSAIVAASMGAKIAKHGNRSVSSKSGASDVLTALSVNVNVTPEQARQALDEIGVCFLFAQQYHSGF
RHVAPVRAALKTRTIFNILGPLINPARPTYHLLGVYAPELVKTYAETAVALEHQHSFVVHGSGLDEVALHGETQVAEIKN
GKIEYFTLTPEDFGLKTQSLESLRGGEPQENAQYLTALLQGKGKAEHANAVAANTALLLKLFGYDDLKQNVQNVLAHLVS
GKAFETLQKLTTY

Sequences:

>Translated_333_residues
MQHNQLLEQLYSGHSLSTSESTALFNAVIQGELSNEQIAAMLIALKVRGANTEEISGAVAASLQNAKAFPYPNYPFADIV
GTGGNGQNTINISTTSAIVAASMGAKIAKHGNRSVSSKSGASDVLTALSVNVNVTPEQARQALDEIGVCFLFAQQYHSGF
RHVAPVRAALKTRTIFNILGPLINPARPTYHLLGVYAPELVKTYAETAVALEHQHSFVVHGSGLDEVALHGETQVAEIKN
GKIEYFTLTPEDFGLKTQSLESLRGGEPQENAQYLTALLQGKGKAEHANAVAANTALLLKLFGYDDLKQNVQNVLAHLVS
GKAFETLQKLTTY
>Mature_333_residues
MQHNQLLEQLYSGHSLSTSESTALFNAVIQGELSNEQIAAMLIALKVRGANTEEISGAVAASLQNAKAFPYPNYPFADIV
GTGGNGQNTINISTTSAIVAASMGAKIAKHGNRSVSSKSGASDVLTALSVNVNVTPEQARQALDEIGVCFLFAQQYHSGF
RHVAPVRAALKTRTIFNILGPLINPARPTYHLLGVYAPELVKTYAETAVALEHQHSFVVHGSGLDEVALHGETQVAEIKN
GKIEYFTLTPEDFGLKTQSLESLRGGEPQENAQYLTALLQGKGKAEHANAVAANTALLLKLFGYDDLKQNVQNVLAHLVS
GKAFETLQKLTTY

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=325, Percent_Identity=57.2307692307692, Blast_Score=347, Evalue=8e-97,
Organism=Saccharomyces cerevisiae, GI6320561, Length=320, Percent_Identity=34.0625, Blast_Score=139, Evalue=6e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35626; Mature: 35626

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHNQLLEQLYSGHSLSTSESTALFNAVIQGELSNEQIAAMLIALKVRGANTEEISGAVA
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
ASLQNAKAFPYPNYPFADIVGTGGNGQNTINISTTSAIVAASMGAKIAKHGNRSVSSKSG
HHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASDVLTALSVNVNVTPEQARQALDEIGVCFLFAQQYHSGFRHVAPVRAALKTRTIFNILG
HHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PLINPARPTYHLLGVYAPELVKTYAETAVALEHQHSFVVHGSGLDEVALHGETQVAEIKN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCCCCEEEEECC
GKIEYFTLTPEDFGLKTQSLESLRGGEPQENAQYLTALLQGKGKAEHANAVAANTALLLK
CEEEEEEECCHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LFGYDDLKQNVQNVLAHLVSGKAFETLQKLTTY
HHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MQHNQLLEQLYSGHSLSTSESTALFNAVIQGELSNEQIAAMLIALKVRGANTEEISGAVA
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
ASLQNAKAFPYPNYPFADIVGTGGNGQNTINISTTSAIVAASMGAKIAKHGNRSVSSKSG
HHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASDVLTALSVNVNVTPEQARQALDEIGVCFLFAQQYHSGFRHVAPVRAALKTRTIFNILG
HHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PLINPARPTYHLLGVYAPELVKTYAETAVALEHQHSFVVHGSGLDEVALHGETQVAEIKN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCCCCEEEEECC
GKIEYFTLTPEDFGLKTQSLESLRGGEPQENAQYLTALLQGKGKAEHANAVAANTALLLK
CEEEEEEECCHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LFGYDDLKQNVQNVLAHLVSGKAFETLQKLTTY
HHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA