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The map label for this gene is fabA [H]

Identifier: 16273235

GI number: 16273235

Start: 1404652

End: 1405185

Strand: Direct

Name: fabA [H]

Synonym: HI1325

Alternate gene names: 16273235

Gene position: 1404652-1405185 (Clockwise)

Preceding gene: 16273234

Following gene: 16273236

Centisome position: 76.75

GC content: 39.7

Gene sequence:

>534_bases
ATGCAAAACGCTTGTACACTTAATAAAAAAAGTAGTTATTCTTATGATGATTTGCTCGCGTCAGGTCGCGGCGAATTATT
TGGTAAAGAAGGCCCGCAATTACCCGCGCCAACAATGTTGATGATGGATCGTATTATTGAAATGAATGAAGAAACAGGTG
CTTTCGGTAAAGGATATATTGAAGCCGAACTTGATATTAAACCTGAATTGCCGTTCTTTGGTTGTCATTTCATTGGCGAT
CCAGTAATGCCAGGTTGTTTAGGATTGGATGCGATGTGGCAGCTTGTTGGGTTTTATTTAGGCTGGATTGGTGGCAAAGG
AAAAGGGCGAGCATTAGGGGTTGGAGAAGTTAAATTCACAGGACAAATTTTGCCAACAGCTAAAAAAGTGGTGTACCGAA
TCCATATGAAACGAGTTATTAATCGTAAACTAGTTATGGGAATGGCTGATGGTGAAGTTGAAGTAGATGGTCGTGTTATT
TATACCGCGACAGATTTAAAAGTGGGACTATTCCAAGATACCTCAACATTTTAA

Upstream 100 bases:

>100_bases
GTTTTGCGAACAAGTGTTAGCTATTTACAGTTTACTGCGTTCCTTTTAAAATAAATATATCAGTTATAAACTGGATTTAT
CATATATAAAGGAATCTGAA

Downstream 100 bases:

>100_bases
TTTTTCTTTATTAATTCATACAAAAGTGCGGTGAAAGTTTTTCCTAGATTTTCACCGCACCTTTACTTATTAAATTGTAA
TAAATTTTTAAAATATCTAT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MQNACTLNKKSSYSYDDLLASGRGELFGKEGPQLPAPTMLMMDRIIEMNEETGAFGKGYIEAELDIKPELPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPTAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSTF

Sequences:

>Translated_177_residues
MQNACTLNKKSSYSYDDLLASGRGELFGKEGPQLPAPTMLMMDRIIEMNEETGAFGKGYIEAELDIKPELPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPTAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSTF
>Mature_177_residues
MQNACTLNKKSSYSYDDLLASGRGELFGKEGPQLPAPTMLMMDRIIEMNEETGAFGKGYIEAELDIKPELPFFGCHFIGD
PVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFTGQILPTAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVI
YTATDLKVGLFQDTSTF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=78.9473684210526, Blast_Score=292, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19465; Mature: 19465

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNACTLNKKSSYSYDDLLASGRGELFGKEGPQLPAPTMLMMDRIIEMNEETGAFGKGYI
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
EAELDIKPELPFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFT
EEEECCCCCCCEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEC
GQILPTAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVIYTATDLKVGLFQDTSTF
CEECCHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MQNACTLNKKSSYSYDDLLASGRGELFGKEGPQLPAPTMLMMDRIIEMNEETGAFGKGYI
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEE
EAELDIKPELPFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWIGGKGKGRALGVGEVKFT
EEEECCCCCCCEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEC
GQILPTAKKVVYRIHMKRVINRKLVMGMADGEVEVDGRVIYTATDLKVGLFQDTSTF
CEECCHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCEEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA