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The map label for this gene is rhtC [C]

Identifier: 16273219

GI number: 16273219

Start: 1385661

End: 1386293

Strand: Direct

Name: rhtC [C]

Synonym: HI1307

Alternate gene names: 16273219

Gene position: 1385661-1386293 (Clockwise)

Preceding gene: 16273218

Following gene: 16273220

Centisome position: 75.71

GC content: 35.39

Gene sequence:

>633_bases
GTGATGCTAAATTTAATCATTGTGCATTTATTTGGATTAATGACGCCAGGGCCTGATTTCTTTTATGTAAGTCGAATGGC
GGCAAGTAACTCTCGTCGTAATACAGTTTGTGGCATTTTAGGCATAACGCTTGGCATCGCCTTTTGGGGAATGCTTTCTA
TGTTGGGATTGGCGGTGTTGTTCGTTACCATTCCAGCATTACATGGCGTTATTATGTTGCTAGGTGGTAGTTACCTAGCA
TATCTCGGTTTTTTAATGGCTCGCAGTAAAAAATACGCTAAATTTGAATCGCACTCTGATACTGAATTTAATCAACAAAC
CACAATCAAAAAAGAAATTTTGAAAGGGCTTTTAGTGAATTTATCCAATGCAAAAGTCGTGGTGTATTTTAGTAGCGTGA
TGTCGCTTGTCTTAGTAAATATCACTGAAATGTGGCAAATTATCTTGGCTTTTGCAGTGATTGTGGTAGAAACATTTTGT
TATTTTTATGTGATTTCATTGATTTTTTCACGTAATATTGCCAAGCGTTTATACAGTCAATACAGCCGTTATATTGATAA
TATGGCAGGTATTGTATTTTTATTTTTTGGTTGTGTGCTTGTTTATAACGGCATCAACGAAATAATTCATTAA

Upstream 100 bases:

>100_bases
TTGACGAAAAACTCGAAAATGGTTTTGGCATTATGATCGATGACGTTTTAGCGGCAATTTATGCTGTGATTGTTGTATTT
GCTATTCAATATTGGATGTT

Downstream 100 bases:

>100_bases
TAGAAAAGGAAGTAACATGACATTAAAAATTGCAATCGCTGGTGCTGGCGGAAGAATGGGGTGTCAATTAATTCAAGCGG
TTCATTCTGCGGAAGGCGTA

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLA
YLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFC
YFYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH

Sequences:

>Translated_210_residues
MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLA
YLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFC
YFYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH
>Mature_210_residues
MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLA
YLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFC
YFYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=38.8349514563107, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786522, Length=200, Percent_Identity=27, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1307_HAEIN (Q57320)

Other databases:

- EMBL:   L42023
- PIR:   F64115
- RefSeq:   NP_439458.1
- GeneID:   950239
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1307
- NMPDR:   fig|71421.1.peg.1245
- TIGR:   HI_1307
- HOGENOM:   HBG759042
- OMA:   FAVIVVE
- ProtClustDB:   CLSK789543
- BioCyc:   HINF71421:HI_1307-MONOMER
- InterPro:   IPR004778
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00949

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 23637; Mature: 23637

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe01b5d4)-; HASH(0xdfcd188)-; HASH(0xe474fec)-; HASH(0xddeab84)-; HASH(0xe2f4a5c)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTIPALHGVIMLLGGSYLAYLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
LSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCYFYVISLIFSRNIAKRLYSQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRYIDNMAGIVFLFFGCVLVYNGINEIIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MMLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTIPALHGVIMLLGGSYLAYLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
LSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCYFYVISLIFSRNIAKRLYSQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRYIDNMAGIVFLFFGCVLVYNGINEIIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800