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The map label for this gene is pgpA

Identifier: 16273218

GI number: 16273218

Start: 1385173

End: 1385664

Strand: Direct

Name: pgpA

Synonym: HI1306

Alternate gene names: 16273218

Gene position: 1385173-1385664 (Clockwise)

Preceding gene: 16273217

Following gene: 16273219

Centisome position: 75.69

GC content: 37.2

Gene sequence:

>492_bases
ATGACAGAAAATAATCCTCTTAAAAAAATCTCTCTTTTAAATCCTATTCATTTACTTGCCGTTGGTTTTGGCTCAGGCTT
AATTCATCCTGCTCCCGGCACTTGGGGGAGCTTAGCTGGAACAATTTTAGGTGTGATTTTACTTTCCTTATTAGGCGTAA
AAATCTTTTTAATTTTCACCGCACTTTGTTTTCTACTCGGTTGCTACCTTTGCCAAAAAACTACTGCAGATATGGGCGTA
CACGATCATGGTTCTATCGTCTGGGATGAATTTGTCGGCGTATTTATTGTATTAGCAGCGATACCGTCATTATCTTGGCA
ATGGATTTTGGCTGCTTTTGCGTTATTCCGCTTTTTTGATATTTTAAAACCGTTTCCAATTCGTTATTTTGACGAAAAAC
TCGAAAATGGTTTTGGCATTATGATCGATGACGTTTTAGCGGCAATTTATGCTGTGATTGTTGTATTTGCTATTCAATAT
TGGATGTTGTGA

Upstream 100 bases:

>100_bases
TTAATGAAAAGTGCGGTGACTTTTCTCCCCGTTTTTTACGGGATGGAAAACCTGTGAATATAACTTTTTCAAGCGGTTTC
GATCATTTTAAGGAATCAAA

Downstream 100 bases:

>100_bases
TGCTAAATTTAATCATTGTGCATTTATTTGGATTAATGACGCCAGGGCCTGATTTCTTTTATGTAAGTCGAATGGCGGCA
AGTAACTCTCGTCGTAATAC

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFTALCFLLGCYLCQKTTADMGV
HDHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFDILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQY
WML

Sequences:

>Translated_163_residues
MTENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFTALCFLLGCYLCQKTTADMGV
HDHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFDILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQY
WML
>Mature_162_residues
TENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFTALCFLLGCYLCQKTTADMGVH
DHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFDILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQYW
ML

Specific function: Specifically hydrolyzes phosphatidylglycerophosphate

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=157, Percent_Identity=49.6815286624204, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGPA_HAEIN (P44157)

Other databases:

- EMBL:   L42023
- PIR:   D64025
- RefSeq:   NP_439457.1
- ProteinModelPortal:   P44157
- SMR:   P44157
- GeneID:   950237
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1306
- NMPDR:   fig|71421.1.peg.1244
- TIGR:   HI_1306
- HOGENOM:   HBG708347
- OMA:   GLGIMVD
- ProtClustDB:   CLSK870222
- BioCyc:   HINF71421:HI_1306-MONOMER
- BRENDA:   3.1.3.27
- InterPro:   IPR007686

Pfam domain/function: PF04608 PgpA; SSF101307 PgpA

EC number: =3.1.3.27

Molecular weight: Translated: 18035; Mature: 17904

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe088c48)-; HASH(0xdd966c8)-; HASH(0xde685ec)-; HASH(0xe37efcc)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALCFLLGCYLCQKTTADMGVHDHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQYWML
HHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TENNPLKKISLLNPIHLLAVGFGSGLIHPAPGTWGSLAGTILGVILLSLLGVKIFLIFT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALCFLLGCYLCQKTTADMGVHDHGSIVWDEFVGVFIVLAAIPSLSWQWILAAFALFRFFD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILKPFPIRYFDEKLENGFGIMIDDVLAAIYAVIVVFAIQYWML
HHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800