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The map label for this gene is ftsW

Identifier: 16273063

GI number: 16273063

Start: 1205069

End: 1206253

Strand: Direct

Name: ftsW

Synonym: HI1137

Alternate gene names: 16273063

Gene position: 1205069-1206253 (Clockwise)

Preceding gene: 16273062

Following gene: 16273064

Centisome position: 65.85

GC content: 34.77

Gene sequence:

>1185_bases
ATGGAATTTTTACAAAATATCAAAAAAAATTACGATGAATGGACACGCATCACACCTCAAGGTTTGTTGTATGATCGCGC
ACTATTTTGGTTATTTGTTATTTTGCTTTTAATTGGTTTAGTGGCAGTAACATCTGCTTCTATTCCTTATAGCTCTCGTT
TATTTAATGATCCTTTTTACTTTGCAAAACGCGACGCTATTTATGTGCTACTTTCTTTACTCACTTGTTATATTTCATTA
CAAATTTCTTCTTCGCAATGGGAAAAATGGCACGCTAAAATTTTTTTATTTTCTGTCATATTATTATTGCTTGTCCCTTT
TATCGGTACATCGGTTAATGGCGCAAAACGTTGGATTTCGTTGGGAATCTTAAACTTTCAACCTGCAGAATTTGCAAAAT
TGGCTTTGACTTGTTTTTTAGCAAGTTATTTCACTCGTCGTTATGATGAAGTGCGGTCGCGACATGTTAGTATTTTTAAA
CCGTTTATTGTTATGCTTGTATTGGGTTGTTTTCTTTTATTGCAACCTGATTTAGGTAGTACAGTCGTGCTATTTATTAT
TATGTCTGGGATGCTTTTTATCGTAGGGGCGAAAATTTTACAGTTTGTAGGATTGATAGCATTAGGTGGAATCTTATTCG
TTTGGCTAGTATTGACCGCCTCTTATCGGTTAAAGCGATTTATAGGTTTTTTAGAACCCTTTAAAGAACCTTATGGCACT
GGTTTCCAATTAACAAACTCTCTTATAGCATTTGGGCGGGGAGAAATTACTGGCGAAGGATTAGGTAATTCAATTCAAAA
ATTAGACTATCTGCCTGAAGCACATACCGATTTCATTATGGCGATTATCGGCGAAGAATTTGGATTTATCGGTATATTGA
TTGTTATTCTTTTATTAGGTTTATTAATTTTTCGTGCAATGAAAATTGGACGAGAATCCTTAATGTTAGAACAACGTTTT
CGAGGTTTTTTTGCATTAGGTATTGGTTTTTGGATTTTCTTTCAAGGCTTTGTGAATTTAGGTATGGCTCTTGGAATGCT
ACCAACTAAAGGTTTAACCTTTCCACTCGTGAGTTATGGTGGTTCGAGTATTATCATTATGTCCGCCACTATTGGTATTT
TATTGCGAATTGATCACGAAAATCGTTTATTTCGTATAGGTCAAGCACGCTTGCGTGATGATTAG

Upstream 100 bases:

>100_bases
TTGTGCAAGTCTCGATCAGTTTGCTTCTTTTGAAAAGCGCGGCGAAGAATTTACGCATTTAGCTCAATGTTTAACCTAAT
TTAGTAACTCACGAAATAAG

Downstream 100 bases:

>100_bases
AGATAGAAAAGATGAAAAATAAAAAATTATTAGTGATGGCGGGTGGTACTGGCGGTCATGTTTTTCCTGCCATTGCAGTT
GCTCAAACTTTACAAAAACA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKEPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD

Sequences:

>Translated_394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKEPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD
>Mature_394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKEPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=371, Percent_Identity=52.5606469002695, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=33.8461538461538, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSW_HAEIN (P45064)

Other databases:

- EMBL:   L42023
- PIR:   C64185
- RefSeq:   NP_439295.1
- GeneID:   950104
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1137
- NMPDR:   fig|71421.1.peg.1090
- TIGR:   HI_1137
- HOGENOM:   HBG729614
- OMA:   YLENEPP
- ProtClustDB:   CLSK869982
- BioCyc:   HINF71421:HI_1137-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- TIGRFAMs:   TIGR02614

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 44553; Mature: 44553

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd8f9f78)-; HASH(0xdbf9b7c)-; HASH(0xdf41924)-; HASH(0xdeb0c6c)-; HASH(0xe09dae4)-; HASH(0xdee1484)-; HASH(0xe1050f0)-; HASH(0xde7ab9c)-; HASH(0xdc130c0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEEEEEEEEEEECCCCCHHHHCHHHCCCH
>Mature Secondary Structure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CCEEEEEEEEEEEEEEECCCCCHHHHCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800