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The map label for this gene is xylB [H]

Identifier: 16273038

GI number: 16273038

Start: 1179231

End: 1180766

Strand: Direct

Name: xylB [H]

Synonym: HI1113

Alternate gene names: 16273038

Gene position: 1179231-1180766 (Clockwise)

Preceding gene: 16273037

Following gene: 16273041

Centisome position: 64.43

GC content: 36.98

Gene sequence:

>1536_bases
ATGAAGCAAAAGTGCGGTTGTATTCCACCGCACTTTTTTATTTTAGGAGACATTATGTATATAGGAATTGATTGTGGCAC
ACAAGGAACAAAGGCGATAGTGCTTGATTCTGTCCAAAAAAAAGTGATTGGAGTTGGTTACGCAAAACATGAATTAATTA
CACAATCCAATGGAAGACGTGAACAACAACCAAATTGGTGGATTGAGGCATTACAACAAGCATTACAAATTGCATTGAAA
CAAGCAAAAAATTCACCGCACTTTTCACCTAATTTAGTGAAGGGAATAGGCATTTCAGGACAACAACATGGACTGGTAAT
GTTAGATAAAAACGATCGTCCTCTATATAAGGCTAAGCTTTGGTGTGATACAGAAACCGCTACGGAAAATGATATACTGA
TCGAAAAATTAGGCGGACAAACAGCCGTATTTGAAAAATTAGGCATCATTTGCCAAACTGGTTACACAGCTTCAAAACTA
AGTTGGTTTCGTCAAAATTATCCTGACAAATTTGCCAATATTCGCAAAATCATGCTGCCACACGATTATCTAAATTATTG
GCTAACAGGAAAATTCTGCACTGAATTTGGTGATGCTTCTGGTAGTGGTTATTTCGATGTTGTGAAAAGAGAATGGAAAA
GAGAAGTCTTCAAATATCTTGCTCCAGAATTAAATATGGATGAAGTGTTACCAAAATTACTTTCTGCTGAACAAAAAATC
GGTGTGATTAAACCTGAAATTGCGACTTTATTTGGTTTTAATGAGAATGTCATCGTCTCCACAGGTGGAGGCGATAATAT
GATGGGAGCAATTGGTACAGGAAATATTCGAGAAGGGATTGCTACGATGAGTCTCGGTACTTCTGGTACCTTGTATGCTT
ATACGCAAAAGCCATTACTTAATTTACCACCAATGATCGCAAATTTTTGTTCAAGTAATAATGGCTGGTTACCACTGGTT
TGTGTAATGAATATAACCTCCTCAAATAAACAGCTAATGAATTTGCTCAATATTGATATTGAAGAATTAAATCAACTTGC
TCAACAAGCACCTATTGGCGCGAATGGCATCACTATTTTGCCATTCTTTAATGGTGAAAGAGTTCCACCTTTACCCAATA
CAAAAGCGAGCATTTTAGGATTAGATTCAAGTAATTTCACACGAGAAAATCTTTGTCGAGCAATGATGGAAAGTGCTACT
TTTACGCTTCGCTATGGCTTAGATTTATTTCGTCAAGCTGGCCTCAAAACCTCACAAATTCGCCTAATTGGAGGTGGCGC
GAAAAGCTCATTTTGGCGGCAAATGATTGCTGATGTGATGAATTCTGAAGTGGTATGTTTGCAGGAAGAAGAAGCTGCTG
CATTAGGAGGAGCAATTCAAGCTATGTGGGCAAATGGAGAAGGAGAACTGGAATTTTTATGCGAAACCTTCATTCACTTA
GATGAAAACTCAAAAGCTTATCCCAACTTATCACAGGTGAAAAATTATCAAAATGCTTATGAGCGTTATTTAACACATTT
ATCACAATTATATTAA

Upstream 100 bases:

>100_bases
TTGCGCAACTTGTCCAACAAAAAGATTTAGCACCAAAACCAGTTTCAGGTCAGCAAGAATATTTGGAAAATTTGGTAAAC
CAAGTTATTTATAGCTAAAA

Downstream 100 bases:

>100_bases
ATAAAATCCCCTATACCGATAAGCTATAGGGGATTTACTACATTAATAATTTATTTTCTATTCAACCACGCCATATATTC
AGTCACGCCTTCCGCAACTG

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKQKCGCIPPHFFILGDIMYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHELITQSNGRREQQPNWWIEALQQALQIALK
QAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAVFEKLGIICQTGYTASKL
SWFRQNYPDKFANIRKIMLPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKI
GVIKPEIATLFGFNENVIVSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLV
CVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESAT
FTLRYGLDLFRQAGLKTSQIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEEAAALGGAIQAMWANGEGELEFLCETFIHL
DENSKAYPNLSQVKNYQNAYERYLTHLSQLY

Sequences:

>Translated_511_residues
MKQKCGCIPPHFFILGDIMYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHELITQSNGRREQQPNWWIEALQQALQIALK
QAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAVFEKLGIICQTGYTASKL
SWFRQNYPDKFANIRKIMLPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKI
GVIKPEIATLFGFNENVIVSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLV
CVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESAT
FTLRYGLDLFRQAGLKTSQIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEEAAALGGAIQAMWANGEGELEFLCETFIHL
DENSKAYPNLSQVKNYQNAYERYLTHLSQLY
>Mature_511_residues
MKQKCGCIPPHFFILGDIMYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHELITQSNGRREQQPNWWIEALQQALQIALK
QAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAVFEKLGIICQTGYTASKL
SWFRQNYPDKFANIRKIMLPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKI
GVIKPEIATLFGFNENVIVSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLV
CVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESAT
FTLRYGLDLFRQAGLKTSQIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEEAAALGGAIQAMWANGEGELEFLCETFIHL
DENSKAYPNLSQVKNYQNAYERYLTHLSQLY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=447, Percent_Identity=24.1610738255034, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=23.3853006681514, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI189409120, Length=449, Percent_Identity=23.3853006681514, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4504007, Length=449, Percent_Identity=23.3853006681514, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI18860918, Length=416, Percent_Identity=21.875, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789987, Length=502, Percent_Identity=33.6653386454183, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=25.5533199195171, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787789, Length=526, Percent_Identity=23.7642585551331, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789168, Length=471, Percent_Identity=22.2929936305732, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554530, Length=517, Percent_Identity=22.4371373307544, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=448, Percent_Identity=21.4285714285714, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321633, Length=535, Percent_Identity=21.8691588785047, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356607, Length=499, Percent_Identity=24.0480961923848, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24655555, Length=507, Percent_Identity=22.2879684418146, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24655560, Length=507, Percent_Identity=22.2879684418146, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24655570, Length=507, Percent_Identity=22.2879684418146, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24655574, Length=507, Percent_Identity=22.2879684418146, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24655565, Length=507, Percent_Identity=22.2879684418146, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 56834; Mature: 56834

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKCGCIPPHFFILGDIMYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHELITQSNGRR
CCCCCCCCCCHHHHHHCEEEEEEECCCCCCCEEEHHHHHHHHHHCCHHHHHHHHCCCCCC
EQQPNWWIEALQQALQIALKQAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEE
WCDTETATENDILIEKLGGQTAVFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIMLP
EECCCCCCCCCEEEECCCCCHHHHHHHCCEEECCCCHHHHHHHHHCCCHHHHHHHHHCCC
HDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKI
HHHHHHEECHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHC
GVIKPEIATLFGFNENVIVSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLL
CCCCCHHHHHCCCCCCEEEECCCCCCCEEECCCCCHHHCCEEEECCCCCEEEEEECCCCC
NLPPMIANFCSSNNGWLPLVCVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITIL
CCCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
PFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTSQI
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCEE
RLIGGGAKSSFWRQMIADVMNSEVVCLQEEEAAALGGAIQAMWANGEGELEFLCETFIHL
EEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCEEEEEECCCCCHHHHHHHHHHC
DENSKAYPNLSQVKNYQNAYERYLTHLSQLY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQKCGCIPPHFFILGDIMYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHELITQSNGRR
CCCCCCCCCCHHHHHHCEEEEEEECCCCCCCEEEHHHHHHHHHHCCHHHHHHHHCCCCCC
EQQPNWWIEALQQALQIALKQAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEE
WCDTETATENDILIEKLGGQTAVFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIMLP
EECCCCCCCCCEEEECCCCCHHHHHHHCCEEECCCCHHHHHHHHHCCCHHHHHHHHHCCC
HDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKI
HHHHHHEECHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHC
GVIKPEIATLFGFNENVIVSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLL
CCCCCHHHHHCCCCCCEEEECCCCCCCEEECCCCCHHHCCEEEECCCCCEEEEEECCCCC
NLPPMIANFCSSNNGWLPLVCVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITIL
CCCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
PFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTSQI
EECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCEE
RLIGGGAKSSFWRQMIADVMNSEVVCLQEEEAAALGGAIQAMWANGEGELEFLCETFIHL
EEEECCCHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCEEEEEECCCCCHHHHHHHHHHC
DENSKAYPNLSQVKNYQNAYERYLTHLSQLY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]