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The map label for this gene is ccmA [H]

Identifier: 16273017

GI number: 16273017

Start: 1153743

End: 1154381

Strand: Direct

Name: ccmA [H]

Synonym: HI1089

Alternate gene names: 16273017

Gene position: 1153743-1154381 (Clockwise)

Preceding gene: 16273006

Following gene: 16273018

Centisome position: 63.04

GC content: 41.78

Gene sequence:

>639_bases
ATGTTTGAGCAACACAAGTTATCTCTGCAAAATTTATCCTGCCAACGTGGTGAGCGCGTACTTTTTCGTGCTTTGACTTG
CGATTTTAATAGCGGTGATTTTGTACAAATTGAAGGGCATAACGGCATAGGTAAAACAAGTTTGTTACGTATTCTTGCGG
GTTTAGTGCGACCTTTGGAAGGCGAAGTGCGGTGGGATTCTGAAGCGATTTCCAAACAACGTGAACAATATCATCAGAAT
TTGCTTTATTTAGGTCATCTTTCTGGTGTTAAACCAGAATTAACCGCATGGGAAAATTTGCAGTTTTATCAACGAATTAG
TCAAGCTGAACAAAACACCGATATGTTGTGGGATTTGCTTGAGAAAGTGGGATTGCTAGGTCGTGAAGATTTGCCGGCTG
CACAACTTTCTGCTGGGCAACAAAAACGTATCGCGTTAGGTCGCTTATGGCTGTCTCAAGCGCCCTTATGGATTTTAGAT
GAGCCCTTTACTGCGATTGATAAAAAAGGCGTGGAAATTCTAACCGCACTTTTTGATGAGCATGCTCAACGAGGTGGTAT
TGTGTTGTTAACCAGCCACCAAGAAGTGCCAAGTTCTCATCTGCAAAAATTGAATTTAGCGGCTTATAAAGCGGAATAA

Upstream 100 bases:

>100_bases
AATAAACCTATCGATCTACTTCTAAAGAGTTATGTGTTTGAGTTGCGAAAATTTCATCAAATATTAGAATACTGTCACTT
TCTATTTTCCCTCTGTAATT

Downstream 100 bases:

>100_bases
CTTAATGATTTTTTTAGAGATAATTAAACGAGAACTTCAAATTGCGATGCGTAAAAATGCGGAAATTTTAAATCCGCTAT
GGTTCTTTTTGCTTGTGATT

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLEGEVRWDSEAISKQREQYHQN
LLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLLEKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILD
EPFTAIDKKGVEILTALFDEHAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE

Sequences:

>Translated_212_residues
MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLEGEVRWDSEAISKQREQYHQN
LLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLLEKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILD
EPFTAIDKKGVEILTALFDEHAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE
>Mature_212_residues
MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLEGEVRWDSEAISKQREQYHQN
LLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLLEKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILD
EPFTAIDKKGVEILTALFDEHAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI46592971, Length=194, Percent_Identity=27.319587628866, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI46592956, Length=194, Percent_Identity=27.319587628866, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI46592915, Length=194, Percent_Identity=27.319587628866, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI46592898, Length=194, Percent_Identity=27.319587628866, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI46592978, Length=194, Percent_Identity=27.319587628866, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI46592964, Length=194, Percent_Identity=27.319587628866, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI47078218, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI45446740, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI215820660, Length=191, Percent_Identity=24.6073298429319, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI20143975, Length=191, Percent_Identity=24.6073298429319, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=28.7128712871287, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI27436953, Length=194, Percent_Identity=29.3814432989691, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI153792144, Length=192, Percent_Identity=27.6041666666667, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082064, Length=207, Percent_Identity=50.2415458937198, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1790467, Length=196, Percent_Identity=27.0408163265306, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87081709, Length=170, Percent_Identity=27.0588235294118, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=159, Percent_Identity=31.4465408805031, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789586, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787105, Length=183, Percent_Identity=27.3224043715847, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788761, Length=169, Percent_Identity=28.4023668639053, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87081834, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI87082267, Length=158, Percent_Identity=28.4810126582279, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1786698, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788165, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786703, Length=173, Percent_Identity=31.2138728323699, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789873, Length=185, Percent_Identity=26.4864864864865, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1787041, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788225, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081782, Length=167, Percent_Identity=28.7425149700599, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787164, Length=191, Percent_Identity=29.3193717277487, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789891, Length=158, Percent_Identity=30.379746835443, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=194, Percent_Identity=26.8041237113402, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081791, Length=172, Percent_Identity=29.0697674418605, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19920532, Length=186, Percent_Identity=28.494623655914, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24580930, Length=186, Percent_Identity=28.494623655914, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24666092, Length=198, Percent_Identity=28.2828282828283, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574744, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24662800, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 24010; Mature: 24010

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLE
CCCCHHHHHHHCCHHHHHHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GEVRWDSEAISKQREQYHQNLLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLL
CCCEECHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
EKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILDEPFTAIDKKGVEILTALFDE
HHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
HAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE
HHCCCCEEEEECCCCCCHHHHHHHHHHEECCC
>Mature Secondary Structure
MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLE
CCCCHHHHHHHCCHHHHHHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
GEVRWDSEAISKQREQYHQNLLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLL
CCCEECHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHH
EKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILDEPFTAIDKKGVEILTALFDE
HHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
HAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE
HHCCCCEEEEECCCCCCHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA