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The map label for this gene is sgbE

Identifier: 16272959

GI number: 16272959

Start: 1090115

End: 1090810

Strand: Reverse

Name: sgbE

Synonym: HI1025

Alternate gene names: 16272959

Gene position: 1090810-1090115 (Counterclockwise)

Preceding gene: 16272960

Following gene: 16272958

Centisome position: 59.6

GC content: 35.2

Gene sequence:

>696_bases
ATGTTAGCACAATTAAAAAAAGAGGTTTTTGAAGCCAATTTAGCATTACCCAAACATCATTTAGTGACTTTTACTTGGGG
TAATGTTTCAGCAATTGATCGTGAAAAAAATTTAGTCGTCATTAAACCATCTGGTGTAGATTATGATGTAATGACAGAAA
ATGATATGGTTGTCGTAGATTTATTTACAGGAAATATTGTTGAAGGCAATAAAAAACCTTCTTCTGACACACCAACTCAT
CTTGAGCTTTATCGACAATTTCCTCATATTGGTGGTATTGTTCATACACATTCTCGACATGCCACAATTTGGGCTCAGGC
TGGCTTAGATATTATTGAGGTGGGAACTACACATGGCGATTATTTTTACGGTACGATTCCTTGTACCCGTCAAATGACAA
CAAAGGAAATAAAAGGTAATTACGAATTAGAAACTGGAAAAGTGATTGTCGAAACTTTTCTTTCGAGAGGAATTGAACCT
GATAATATTCCGGCGGTATTAGTGCATAGTCATGGCCCATTTGCTTGGGGAAAAGATGCAAATAATGCGGTACATAATGC
CGTTGTTTTAGAAGAAGTTGCTTATATGAACTTATTTTCTCAGCAACTTAATCCTTATCTATCTCCTATGCAAAAAGATC
TATTGGATAAACATTATCTACGCAAACATGGTCAAAATGCCTATTATGGTCAATGA

Upstream 100 bases:

>100_bases
TCTTAATTGAAATGTGGACAGAAAAAAATGAAGAACCCTTATTAGAAATTATTCAAGCTCGTAAGTGGATAGTTCAACAA
ATGGAAAAGGCAGGATTATT

Downstream 100 bases:

>100_bases
ATTAAAGACAGAATTATACTGCCTTCCTCATATTATTTAAGGAAAAACGATGGGAAAACCTTTATTACAAATCGCTCTTG
ATGCCCAATATTTAGAGACT

Product: L-ribulose-5-phosphate 4-epimerase

Products: D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVDLFTGNIVEGNKKPSSDTPTH
LELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGDYFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEP
DNIPAVLVHSHGPFAWGKDANNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ

Sequences:

>Translated_231_residues
MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVDLFTGNIVEGNKKPSSDTPTH
LELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGDYFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEP
DNIPAVLVHSHGPFAWGKDANNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ
>Mature_231_residues
MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVDLFTGNIVEGNKKPSSDTPTH
LELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGDYFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEP
DNIPAVLVHSHGPFAWGKDANNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ

Specific function: Probable pentulose-5-phosphate-4-epimerase

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily

Homologues:

Organism=Escherichia coli, GI1790008, Length=231, Percent_Identity=73.1601731601732, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1786247, Length=231, Percent_Identity=72.2943722943723, Blast_Score=353, Evalue=4e-99,
Organism=Escherichia coli, GI1790642, Length=230, Percent_Identity=62.1739130434783, Blast_Score=305, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SGBE_HAEIN (P44989)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_439185.1
- ProteinModelPortal:   P44989
- SMR:   P44989
- GeneID:   950011
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1025
- NMPDR:   fig|71421.1.peg.987
- TIGR:   HI_1025
- HOGENOM:   HBG541069
- OMA:   ELYRQFP
- ProtClustDB:   PRK12347
- BioCyc:   HINF71421:HI_1025-MONOMER
- InterPro:   IPR001303
- InterPro:   IPR004661
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR00760

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: 5.1.3.4

Molecular weight: Translated: 25981; Mature: 25981

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVD
CHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCEEEECCCCCCEEEEECCCEEEEE
LFTGNIVEGNKKPSSDTPTHLELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGD
EEECCEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCC
YFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEPDNIPAVLVHSHGPFAWGKDA
EEEEECCCCCCHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
NNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVD
CHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCEEEECCCCCCEEEEECCCEEEEE
LFTGNIVEGNKKPSSDTPTHLELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGD
EEECCEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCC
YFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEPDNIPAVLVHSHGPFAWGKDA
EEEEECCCCCCHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
NNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ribulose 5-phosphate

Specific reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800